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University of North Carolina-Chapel Hill: Dataset Details, ID=GSE115641

Superfund Research Program

Genomic and Genetic Analysis of Liver and Kidney Toxicity of Trichloroethylene

Project Leader: Ivan Rusyn (Texas A&M University)
Grant Number: P42ES005948
Funding Period: 2006-2017
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Title: Nonalcoholic fatty liver, but not nonalcoholic steatohepatitis is a protective factor to tetrachloroethylene-associated kidney effects in male C57BL/6J mice

Accession Number: GSE115641

Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE115641

Repository: Gene Expression Omnibus (GEO)

Data Type(s): Gene Expression

Experiment Type(s): Expression profiling by high throughput sequencing

Organism(s): Mus musculus

Summary: Purpose: We investigated the tetrachloroethylene associated changes in kidney transcriptomes among healthy mice, nonalcoholic fatty liver disease mice, and nonalcoholic steatohepatitis mice.

Publication(s) associated with this dataset:
  • Cichocki JA, Luo Y, Furuya S, Venkatratnam A, Konganti K, Chiu WA, Threadgill DW, Pogribny IP, Rusyn I. 2018. Modulation of Tetrachloroethylene-Associated Kidney Effects by Nonalcoholic Fatty Liver or Steatohepatitis in Male C57BL/6J Mice. Toxicol Sci 167(1):126-137. doi:10.1093/toxsci/kfy223 PMID:30202895 PMCID:PMC6317418
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