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University of North Carolina-Chapel Hill: Dataset Details, ID=GSE67976

Superfund Research Program

Elucidating Mechanisms of Heavy Metal-Induced Toxicity and Disease

Project Leader: Rebecca C. Fry
Grant Number: P42ES005948
Funding Period: 2011-2018
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Title: CpG island methylation data from maternal venous blood and infant cord blood samples

Accession Number: GSE67976

Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE67976

Repository: Gene Expression Omnibus (GEO)

Data Type(s): Gene Expression

Experiment Type(s): Methylation profiling by genome tiling array

Organism(s): Homo sapiens

Summary: The biological mechanism of cadmium's effects is poorly characterized. This data was generated in order to help better understand the epigenetic role that Cadmium plays. We used the MIRA assay and the Affymetrix Human Promoter 1.0R Array in order to measure methylation levels in promoter regions.

Publication(s) associated with this dataset:
  • Sanders AP, Smeester L, Rojas D, DeBussycher T, Wu MC, Wright FA, Zhou Y, Laine JE, Rager JE, Swamy GK, Ashley-Koch A, Miranda ML, Fry RC. 2013. Cadmium exposure and the epigenome: Exposure-associated patterns of DNA methylation in leukocytes from mother-baby pairs. Epigenetics 9(2):29-38. doi:10.4161/epi.26798 PMID:24169490 PMCID:PMC3962531
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