Superfund Research Program
Chemistry and Analytical Core
Project Leader: Avram Gold
Co-Investigator: Wanda M. Bodnar
Grant Number: P42ES005948
Funding Period: 1995-2018
Project-Specific Links
Title: Effects of trichloroethylene in males of 17 inbred mouse strains
Accession Number: Rusyn2
Link to Dataset: https://phenome.jax.org/projects/Rusyn2
Repository: Mouse Phenome Database (MPD)
Data Type(s): Genotype/Phenotype
Experiment Type(s): Phenotype measurements
Organism(s): Mus musculus
Summary: An investigation into the effects of trichloroethylene. There were 3 cohorts: 1) naive mice; 2) control group orally administered vehicle (corn oil); 3) treated group orally administered trichloroethylene (TCE 2100 mg/kg) in vehicle.
Publication(s) associated with this dataset:- Yoo HS, Bradford BU, Kosyk O, Shymonyak S, Uehara T, Collins LB, Bodnar WM, Ball LM, Gold A, Rusyn I. 2015. Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: liver effects. J Toxicol Environ Health A 78(1):15-31. doi:10.1080/15287394.2015.958417 PMID:25424544 PMCID:PMC4281929
- Yoo HS, Bradford BU, Kosyk O, Uehara T, Shymonyak S, Collins LB, Bodnar WM, Ball LM, Gold A, Rusyn I. 2015. Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: kidney effects. J Toxicol Environ Health A 78(1):32-49. doi:10.1080/15287394.2015.958418 PMID:25424545 PMCID:PMC4281933