Superfund Research Program
Superfund Chemicals, Nutrition, and Multi-Organ Cardiovascular Risk
Project Leader: Bernhard Hennig
Co-Investigator: Hunter Nathaniel Moseley
Grant Number: P42ES007380
Funding Period: 1997-2025
Project-Specific Links
Datasets
News Items
Final Progress Reports
Publications
Research BriefsConnect with the Grant Recipients
Title: Profile of microRNAs in human umblical vein endothelial cells (HUVECs)
Accession Number: GSE79005
Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE79005
Repository: Gene Expression Omnibus (GEO)
Data Type(s): Gene Expression
Organism(s): Homo sapiens
Summary: Polychlorinated biphenyl exposure alters the expression profile of microRNAs in HUVECs. Primary human endothelial cells (HUVECs) were exposed to the commercial PCB mixture, Aroclor 1260, at 10 microM. After a 16-h exposure, RNA was extracted and hybridized on Affymetrix microarrays. Samples were analyzed using Affymetrix GeneChip miRNA 4.0 arrays for high throughput detection.
Publication(s) associated with this dataset:- Wahlang B, Petriello MC, Perkins JT, Shen S, Hennig B. 2016. Polychlorinated biphenyl exposure alters the expression profile of microRNAs associated with vascular diseases. Toxicol In Vitro 35:180-187. doi:10.1016/j.tiv.2016.06.001 PMID:27288564 PMCID:PMC4949395