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Your Environment. Your Health.

News Items: University of Kentucky

Superfund Research Program

Superfund Chemicals, Nutrition, and Multi-Organ Cardiovascular Risk

Project Leader: Bernhard Hennig
Co-Investigator: Hunter Nathaniel Moseley
Grant Number: P42ES007380
Funding Period: 1997-2025
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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News Items List

  • High-Fiber Diet May Protect Against Harmful Health Effects of PCBs
    Research Brief - March 2020
    Two new NIEHS-funded Superfund Research Program (SRP) studies showed how a type of dietary fiber, inulin, may protect against heart disease, including heart disease resulting from exposure to polychlorinated biphenyls (PCBs). According to University of Kentucky SRP Center researchers, a diet high in inulin may reduce or modify certain lipids associated with an increased chance of developing cardiovascular problems and may protect against adverse cardiovascular effects caused by environmental toxicants.
  • PCBs Increase Inflammation, Disrupt Gut Microbiome, and Alter Metabolism
    Research Brief - November 2018
    Researchers have discovered that exposure to certain polychlorinated biphenyls (PCBs) can increase inflammation in the intestines, alter normal gut microbiota, and disrupt metabolism. They suggest that some of the observed health impacts of PCBs may be initiated in the gut and that changes in the gut microbiota may offer a marker for pollutant exposures.
  • A Link Between Exposure to PCBs, Diet, and Cardiovascular Disease
    Research Brief - November 2016
    Researchers at the University of Kentucky Superfund Research Program (UK SRP) Center have identified a new mechanism linking exposure to polychlorinated biphenyls (PCBs) and cardiovascular disease (CVD). They revealed that PCBs can lead to increased production of a biological marker of CVD, which is also linked to consumption of red meat and other animal products, revealing a novel diet-toxicant interaction associated with CVD risk.
  • Researchers discover new diet-toxicant interaction
    Paper of the Month - September 2016
    An NIEHS grantee and colleagues have identified a new interaction that may link exposure to polychlorinated biphenyls (PCBs) with cardiovascular disease. Although their manufacture and use are now banned in the United States, PCBs break down slowly, so they remain in the environment for long periods of time.
  • Wetterhahn winner reflects on lessons from multidisciplinary research
    Environmental Factor - June 2016
    Bradley Newsome, Ph.D., winner of the 17th Karen Wetterhahn Memorial Award , discussed his progression from graduate student in the University of Kentucky (UK) Superfund Research Program (SRP) Center to his current policy work at the National Institutes of Health (NIH). 
  • Two SRP grantees selected as prestigious AAAS fellows
    Environmental Factor - September 2015
    his month, NIEHS Superfund Research Program (SRP) researchers Wendy Heiger-Bernays, Ph.D., and Bradley Newsome, Ph.D., join an elite group of scientists and engineers as American Association for the Advancement of Science (AAAS) Science and Technology Policy Fellows to help connect good science to government decision-making.
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