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Your Environment. Your Health.

New York University School of Medicine: Dataset Details, ID=GSE40392

Superfund Research Program

Carcinogenic Metals and Their Interactions With Other Toxicants (ARRA Funded)

Center Director: Max Costa
Grant Number: P42ES010344
Funding Period: 2000-2006 and 2009-2011

Title: Gene expression of PBMC of chinese nickel refinery workers when compared to the gene expression profile of PBMCs from referent subjects

Accession Number: GSE40392

Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE40392

Repository: Gene Expression Omnibus (GEO)

Data Type(s): Gene Expression

Experiment Type(s): Expression profiling by array

Organism(s): Homo sapiens

Summary: Up to date the studies examining the gene expression profiles in response to exposure to nickel compounds have only been conducted using in vitro tissue culture systems. Here, we have compared the gene expression profiles in peripheral blood mononuclear cells (PMCs) of eight nickel refinery workers in Jinchang, China to the expression profiles of referent subjects with only environmental exposure.

Publication(s) associated with this dataset:
  • Arita A, Munoz A, Chervona Y, Niu J, Qu Q, Zhao N, Ruan Y, Kiok K, Kluz T, Sun H, Clancy HA, Shamy MY, Costa M. 2013. Gene expression profiles in peripheral blood mononuclear cells of Chinese nickel refinery workers with high exposures to nickel and control subjects. Cancer Epidemiol Biomarkers Prev 22(2):261-269. doi:10.1158/1055-9965.epi-12-1011 PMID:23195993 PMCID:PMC3565097
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