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Baylor College of Medicine: Dataset Details, ID=GSE169197

Superfund Research Program

Data Management and Analysis Core

Project Leader: Susan G. Hilsenbeck
Co-Investigator: Cristian Coarfa
Grant Number: P42ES027725
Funding Period: 2020-2025
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Title: Single-cell RNAseq of the murine intestinal epithelium infected with rotavirus

Accession Number: GSE169197

Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE169197

Repository: Gene Expression Omnibus (GEO)

Data Type(s): Gene Expression

Experiment Type(s): Expression profiling by high throughput sequencing

Organism(s): Mus musculus

Summary: o understand the impact of murine rotavirus infection on mouse intestinal epithelial tissue, we isolated total intestinal epithelium from uninfected and infected C57Bl6J mice and performed single-cell RNAseq.

Publication(s) associated with this dataset:
  • Bomidi C, Robertson M, Coarfa C, Estes MK, Blutt SE. 2021. Single-cell sequencing of rotavirus-infected intestinal epithelium reveals cell-type specific epithelial repair and tuft cell infection. Proc Natl Acad Sci U S A 118(45):doi:10.1073/pnas.2112814118 PMID:34732579 PMCID:PMC8609316
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