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Person Details: Stephania A. Cormier

Superfund Research Program

Stephania A. Cormier

Louisiana State University
Pennington Biomedical Research Center
6400 Perkins Rd
Baton Rouge, Louisiana 70808
Phone: 225-763-2691


Research Briefs

Hazardous Waste Sites

Clean Harbors, Colfax, Louisiana

  • Louisiana State University: Community Engagement Core
  • Louisiana State University: Hazardous Waste Thermal Treatment and Community Exposure to Environmentally Persistent Free Radicals

Delta Shipyard

  • Louisiana State University: Community Engagement Core

Devil's Swamp Lake

  • Louisiana State University: Community Engagement Core

Dutchtown Treatment Plant

  • Louisiana State University: Community Engagement Core

Louisiana Army Ammunition Plant

  • Louisiana State University: Community Engagement Core

Radford Army Ammunition Plant, Radford, VA

  • Louisiana State University: Community Engagement Core
  • Louisiana State University: Hazardous Waste Thermal Treatment and Community Exposure to Environmentally Persistent Free Radicals

Ruston Foundry

  • Louisiana State University: Community Engagement Core



  • Aryal A, Noel A, Khachatryan L, Cormier SA, Chowdhury PH, Penn A, Dugas TR, Harmon AC. 2023. Environmentally persistent free radicals: Methods for combustion generation, whole-body inhalation and assessing cardiopulmonary consequences. Environ Pollut 334:122183. doi:10.1016/j.envpol.2023.122183 PMID:37442324
  • Yu Q, Cao W, Hamer D, Urbanek N, Straif-Bourgeois S, Cormier SA, Ferguson T, Richmond-Bryant J. 2023. Associations of COVID-19 hospitalizations, ICU admissions, and mortality with Black and White race by air pollution and other risk factors in the Louisiana Industrial Corridor, March, 2020 - August, 2021. J Racial Ethn Health Disparities 20(5):4611. doi:10.3390/ijerph20054611 PMID:36901619 PMCID:PMC10001987


  • Noel A, Ashbrook DG, Xu F, Cormier SA, Lu L, O'Callaghan JP, Menon SK, Zhao W, Penn A, Jones BC. 2022. Genomic basis for individual differences in susceptibility to the neurotoxic effects of diesel exhaust. Int J Mol Sci 23(20):12461. doi:10.3390/ijms232012461 PMID:36293318 PMCID:PMC9603950


  • Christofferson RC, O'Neal HR, Jagneaux T, O'Neal C, Walsh CS, Mayton EH, Vu LD, Fish AI, Phan AT, Stoufflet TE, Schroeder JR, Walker M, Turner EA, Pierce C, Wester KS, DeLeo C, Tenreiro E, Ogden B, Cormier SA. 2021. Reduced turnaround times through multi-sectoral community collaboration during the first surge of SARS-CoV-2 and associated effect on patient care and hospital operations. PLoS One 16(10):e0257302. doi:10.1371/journal.pone.0257302 PMID:34618831 PMCID:PMC8496830
  • Guan X, Truong L, Lomnicki S, Tanguay RL, Cormier SA. 2021. Developmental hazard of environmentally persistent free radicals and protective effect of TEMPOL in zebrafish model. Toxics 9:doi:10.3390/toxics9010012 PMID:33467068 PMCID:PMC7829864
  • Harding JN, Gross M, Potter S, Patel V, Cormier SA. 2021. Association between particulate matter containing EPFRs and neutrophilic asthma through AhR and Th17. Respir Res 22(275):doi:10.1186/s12931-021-01867-w PMID:34702270 PMCID:PMC8549224
  • Kumar A, Patel VS, Harding JN, You D, Cormier SA. 2021. Exposure to combustion derived particulate matter exacerbates influenza infection in neonatal mice by inhibiting IL22 production. Part Fibre Toxicol 18(1):43. doi:10.1186/s12989-021-00438-7 PMID:34906172 PMCID:PMC8670221
  • Liu J, Li S, Fei X, Nan X, Shen Y, Xiu H, Cormier SA, Lu C, Guo C, Wang S, Cai Z, Wang P. 2021. Increased alveolar epithelial TRAF6 via autophagy-dependent TRIM37 degradation mediates particulate matter-induced lung metastasis. Autophagy doi:10.1080/15548627.2021.1965421 PMID:34524943
  • Oyana T, Minso J, Jones TL, McCullers JA, Arnold SR, Cormier SA. 2021. Particulate matter exposure predicts residence in high-risk areas for community acquired pneumonia among hospitalized children. Exp Biol Med (Maywood) 246(17):1907-1916. doi:10.1177/15353702211014456 PMID:34053235 PMCID:PMC8424632
  • Sly PD, Trottier BA, Bulka C, Cormier SA, Fobil J, Fry RC, Kim K, Kleeberger SR, Kumar P, Landrigan PJ, Lodrop Carlsen KC, Pascale A, Polack FP, Ruchirawat K, Zar H, Suk WA. 2021. The interplay between environmental exposures and COVID-19 risks in the health of children. Environ Health 20(1):34. doi:10.1186/s12940-021-00716-z PMID:33771185 PMCID:PMC7996114
  • Violi A, Cormier SA, Gullett BK, Jansson S, Lomnicki S, Luyet C, Mayer A, Zimmermann R. 2021. Combustion by-products and their health effects: Summary of the 16th international congress. Fuel 283:118562. doi:10.1016/j.fuel.2020.118562 PMID:33446939 PMCID:PMC7802799
  • Yamamoto A, Yeo AJ, Sly PD, Cormier SA, Lomnicki S, Khachatryan L, Fantino E. 2021. The effect of combustion generated environmentally persistent free radicals on well-differentiated human airway epithelial cells. Am J Respir Crit Care Med 203:doi:10.1164/ajrccm-conference.2021.203.1



  • Hijano DR, Vu LD, Kauvar LM, Tripp RA, Polack FP, Cormier SA. 2019. Role of Type I Interferon (IFN) in the Respiratory Syncytial Virus (RSV) Immune Response and Disease Severity. Front Immunol 10:14. doi:10.3389/fimmu.2019.00566 PMID:30972063 PMCID:PMC6443902
  • Immanuel CN, Teng B, Dong B, Gordon EM, Kennedy JA, Luellen C, Schwingshackl A, Cormier SA, Fitzpatrick E, Waters CM. 2019. Apoptosis signal-regulating kinase-1 promotes inflammasome priming in macrophages. Am J Physiol Lung Cell Mol Physiol 316:418-427. doi:10.1152/ajplung.00199.2018 PMID:30628485 PMCID:PMC6459294
  • Sly PD, Cormier SA, Lomnicki S, Harding JN, Grimwood K. 2019. Environmentally Persistent Free Radicals: Linking Air Pollution and Poor Respiratory Health?. Am J Respir Crit Care Med 1062-1063. doi:10.1164/rccm.201903-0675LE PMID:31237999 PMCID:PMC7330507
  • Sly PD, Trottier BA, Carpenter DO, Cha'on U, Cormier SA, Galluzzo B, Ghosh S, Goldizen FC, Heacock M, Jagals P, Joshi H, Kathuria P, Ha L, Magsumbol MS, Navasumrit P, Prabhakaran P, Sen B, Skelly C, Suraweera I, Vong S, Wangdi C, Suk WA. 2019. Children's environmental health in South and Southeast Asia: Networking for better child health outcomes. Ann Glob Health 85:doi:10.5334/aogh.2403 PMID:30873796 PMCID:PMC6571144
  • Vu LD, Siefker D, Jones TL, You D, Taylor R, DeVincenzo JP, Cormier SA. 2019. Elevated Levels of Type 2 Respiratory Innate Lymphoid Cells in Human Infants with Severe Respiratory Syncytial Virus Bronchiolitis. Am J Respir Crit Care Med 1414-1423. doi:10.1164/rccm.201812-2366OC PMID:31237777 PMCID:PMC6884055


  • Harmon AC, Hebert VY, Cormier SA, Subramanian B, Reed JR, Backes WL, Dugas TR. 2018. Particulate matter containing environmentally persistent free radicals induces AhR-dependent cytokine and reactive oxygen species production in human bronchial epithelial cells. PLoS One 13:18. doi:10.1371/journal.pone.0205412 PMID:30308017 PMCID:PMC6181347
  • Hijano DR, Siefker DT, Shrestha B, Jaligama S, Vu LD, Tillman H, Finkelstein D, Saravia J, You D, Cormier SA. 2018. Type I Interferon Potentiates IgA Immunity to Respiratory Syncytial Virus Infection During Infancy. Sci Rep 8:12. doi:10.1038/s41598-018-29456-w PMID:30038294 PMCID:PMC6056463
  • Jaligama S, Patel VS, Wang P, Sallam AA, Harding JN, Kelley MA, Mancuso SR, Dugas TR, Cormier SA. 2018. Radical containing combustion derived particulate matter enhance pulmonary Th17 inflammation via the aryl hydrocarbon receptor. Part Fibre Toxicol 15:20. doi:10.1186/s12989-018-0255-3 PMID:29724254
  • Vejerano E, Rao G, Khachatryan L, Cormier SA, Lomnicki S. 2018. Environmentally persistent free radicals: insights on a new class of pollutants. Environ Sci Technol 52:2468-2481. doi:10.1021/acs.est.7b04439 PMID:29443514


  • Fitzpatrick E, You D, Shrestha B, Siefker DT, Patel VS, Yadav N, Jaligama S, Cormier SA. 2017. A neonatal murine model of MRSA pneumonia. PLoS One 12(1):e0169273. doi:10.1371/journal.pone.0169273 PMID:28060871 PMCID:PMC5218573
  • Jaligama S, Saravia J, You D, Yadav N, Lee GI, Shrestha B, Cormier SA. 2017. Regulatory T cells and IL10 suppress pulmonary host defense during early-life exposure to radical containing combustion derived ultrafine particulate matter. Respir Res 18(1):15. doi:10.1186/s12931-016-0487-4 PMID:28086957 PMCID:PMC5237352
  • Oyana T, Lomnicki S, Guo C, Cormier SA. 2017. A scalable field study protocol and rationale for passive ambient air sampling: a spatial phytosampling for leaf data collection. Environ Sci Technol 51(18):10663-10673. doi:10.1021/acs.est.7b03643 PMID:28805054
  • Oyana T, Podila P, Wesley J, Lomnicki S, Cormier SA. 2017. Spatiotemporal patterns of childhood asthma hospitalization and utilization in Memphis Metropolitan Area from 2005 to 2015. J Asthma 5:1-14. doi:10.1080/02770903.2016.1277537 PMID:28055280
  • Shrestha B, You D, Saravia J, Siefker DT, Jaligama S, Lee GI, Sallam AA, Harding JN, Cormier SA. 2017. IL-4R alpha on dendritic cells in neonates and Th2 immunopathology in respiratory syncytial virus infection. J Leukoc Biol 102:153-161. doi:10.1189/jlb.4A1216-536R PMID:28389622 PMCID:PMC5470835


  • Chen Z, Wu Y, Wang P, Wu Y, Li Z, Zhao Y, Zhou J, Zhu C, Cao C, Mao Y, Xu F, Wang B, Cormier SA, Ying S, Li W, Shen H. 2016. Autophagy is essential for ultrafine particle-induced inflammation and mucus hyperproduction in airway epithelium. Autophagy 12(2):297-311. doi:10.1080/15548627.2015.1124224 PMID:26671423 PMCID:PMC5044763
  • Dugas TR, Lomnicki S, Cormier SA, Dellinger B, Reams MA. 2016. Addressing emerging risks: scientific and regulatory challenges associated with environmentally persistent free radicals. Int J Environ Res Public Health 13(6):573. doi:10.3390/ijerph13060573 PMID:27338429 PMCID:PMC4924030
  • Kimura D, Saravia J, Rovnaghi C, Meduri UG, Schwingshackl A, Cormier SA, Anand KJ. 2016. Plasma biomarker analysis in pediatric ARDS: generating future framework from a pilot randomized control trial of methylprednisolone: a framework for identifying plasma biomarkers related to clinicaloutcomes in pediatric ARDS. Front Pediatr 4:31. doi:10.3389/fped.2016.00031 PMID:27066464 PMCID:PMC4815896
  • Schwingshackl A, Kimura D, Rovnaghi C, Saravia J, Cormier SA, Teng B, West AN, Meduri UG, Anand KJ. 2016. Regulation of inflammatory biomarkers by intravenous methylprednisolone in pediatric ARDS patients: results from a double-blind, placebo-controlled randomized pilot trial. Cytokine 77:63-71. doi:10.1016/j.cyto.2015.10.007 PMID:26545141 PMCID:PMC4666843
  • Stephenson EJ, Ragauskas A, Jaligama S, Redd JR, Parvathareddy J, Saravia J, Han JC, Cormier SA, Bridges D. 2016. Exposure to environmentally persistent free radicals during gestation lowers energy expenditure and impairs skeletal muscle mitochondrial function in adult mice. Am J Physiol Endocrinol Metab 310(11):E1003-E1015. doi:10.1152/ajpendo.00521.2015 PMID:27117006 PMCID:PMC4935140
  • Weidemann E, Andersson PL, Bidleman T, Boman C, Carlin DJ, Collina E, Cormier SA, Gouveia-Figueira SC, Gullett BK, Johansson C, Lucas D, Lundin L, Lundstedt S, Marklund S, Nording M, Ortuno N, Sallam AA, Schmidt FM, Jansson S. 2016. 14th congress of combustion by-products and their health effects-origin, fate, and health effects of combustion-related air pollutants in the coming era of bio-based energy sources. Environ Sci Pollut Res Int 23(8):8141-8159. doi:10.1007/s11356-016-6308-y PMID:26906006


  • Hrincius ER, Liedmann S, Finkelstein D, Vogel P, Gansebom S, Samarasinghe AE, You D, Cormier SA, McCullers JA. 2015. Acute lung injury results from innate sensing of viruses by an ER stress pathway. Cell Rep 11(10):1591-1603. doi:10.1016/j.celrep.2015.05.012 PMID:26051937 PMCID:PMC4682876
  • Huang H, Saravia J, You D, Shaw AJ, Cormier SA. 2015. Impaired gamma delta T cell-derived IL-17A and inflammasome activation during early respiratory syncytial virus infection in infants. Immunol Cell Biol 93(2):126-135. doi:10.1038/icb.2014.79 PMID:25267484 PMCID:PMC4323740
  • Jaligama S, Chen Z, Saravia J, Yadav N, Lomnicki S, Dugas TR, Cormier SA. 2015. Exposure to deepwater horizon crude oil burnoff particulate matter induces pulmonary inflammation and alters adaptive immune response. Environ Sci Technol 49(14):8769-8776. doi:10.1021/acs.est.5b01439 PMID:26115348 PMCID:PMC4526136
  • Nau F, Miller J, Saravia J, Ahlert TA, Yu B, Happel KI, Cormier SA, Nichols CD. 2015. Serotonin 5-HT₂ receptor activation prevents allergic asthma in a mouse model. Am J Physiol 308(2):L191-L198. doi:10.1152/ajplung.00138.2013 PMID:25416380 PMCID:PMC4338939
  • Oyana T, Matthews-Juarez P, Cormier SA, Xu X, Juarez PD. 2015. Using an external exposome framework to examine pregnancy-related morbidities and mortalities: implications for health disparities research. Int J Environ Res Public Health 13(1):ijerph13010013. doi:10.3390/ijerph13010013 PMID:26703702 PMCID:PMC4730404
  • Saravia J, You D, Shrestha B, Jaligama S, Siefker DT, Lee GI, Harding JN, Jones TL, Rovnaghi C, Bagga B, DeVincenzo JP, Cormier SA. 2015. Respiratory syncytial virus disease is mediated by age-variable IL-33. PLoS Pathog 11(10):e1005217. doi:10.1371/journal.ppat.1005217 PMID:26473724 PMCID:PMC4608776
  • Sussan TE, Gajghate S, Thimmulappa RK, Ma J, Kim J, Sudini K, Consolini N, Cormier SA, Lomnicki S, Hasan F, Pekosz A, Biswal S. 2015. Exposure to electronic cigarettes impairs pulmonary anti-bacterial and anti-viral defenses in a mouse model. PLoS One 10(2):e0116861. doi:10.1371/journal.pone.0116861 PMID:25651083 PMCID:PMC4317176
  • You D, Saravia J, Siefker DT, Shrestha B, Cormier SA. 2015. Crawling with virus: translational insights from a neonatal mouse model on the pathogenesis of respiratory syncytial virus in infants. J Virol 90(1):2-4. doi:10.1128/JVI.01026-15 PMID:26446604 PMCID:PMC4702544
  • You D, Siefker DT, Shrestha B, Saravia J, Cormier SA. 2015. Building a better neonatal mouse model to understand infant respiratory syncytial virus disease. Respir Res 16:91. doi:10.1186/s12931-015-0244-0 PMID:26231396 PMCID:PMC4531813


  • Cormier SA, Shrestha B, Saravia J, Lee GI, Shen L, DeVincenzo JP, Kim Y, You D. 2014. Limited type I interferons and plasmacytoid dendritic cells during neonatal respiratory syncytial virus infection permit immunopathogenesis upon reinfection. J Virol 88(16):9350-9360. doi:10.1128/JVI.00818-14 PMID:24920801 PMCID:PMC4136292
  • Lee GI, Saravia J, You D, Shrestha B, Jaligama S, Hebert VY, Dugas TR, Cormier SA. 2014. Exposure to combustion generated environmentally persistent free radicals enhances severity of influenza virus infection. Part Fibre Toxicol 11:57. doi:10.1186/s12989-014-0057-1 PMID:25358535 PMCID:PMC4222384
  • Lomnicki S, Gullett BK, Stoger T, Kennedy I, Diaz J, Dugas TR, Varner KJ, Carlin DJ, Dellinger B, Cormier SA. 2014. Combustion by-products and their health effects--combustion engineering and global health in the 21st century: issues and challenges. Int J Toxicol 33(1):3-13. doi:10.1177/1091581813519686 PMID:24434722 PMCID:PMC3944372
  • Saravia J, You D, Thevenot PT, Lee GI, Shrestha B, Lomnicki S, Cormier SA. 2014. Early-life exposure to combustion-derived particulate matter causes pulmonary immunosuppression. Mucosal Immunol 7(3):694-704. doi:10.1038/mi.2013.88 PMID:24172848 PMCID:PMC3999175
  • Schwingshackl A, Teng B, Makena P, Ghosh M, Sinclair SE, Luellen C, Balasz L, Rovnaghi C, Bryan RM, Lloyd EE, Fitzpatrick E, Saravia J, Cormier SA, Waters CM. 2014. Deficiency of the two-pore-domain potassium channel TREK-1 promotes hyperoxia-induced lung injury. Crit Care Med 42(11):e692-e701. doi:10.1097/CCM.0000000000000603 PMID:25126877 PMCID:PMC4199872


  • Kelley MA, Hebert VY, Thibeaux TM, Orchard MA, Hasan F, Cormier SA, Thevenot PT, Lomnicki S, Varner KJ, Dellinger B, Latimer BM, Dugas TR. 2013. Model combustion-generated particulate matter containing persistent free radicals redox cycle to produce reactive oxygen species. Chem Res Toxicol 26(12):1862-1871. doi:10.1021/tx400227s PMID:24224526 PMCID:PMC4112599
  • Saravia J, Lee GI, Lomnicki S, Dellinger B, Cormier SA. 2013. Particulate matter containing environmentally persistent free radicals and adverse infant respiratory health effects: A review. J Biochem Mol Toxicol 27(1):56-68. doi:10.1002/jbt.21465 PMID:23281110 PMCID:PMC3580159
  • Thevenot PT, Saravia J, Giaimo JD, Happel KI, Dugas TR, Cormier SA. 2013. Chronic alcohol induces M2 polarization enhancing pulmonary disease caused by exposure to particulate air pollution. Alcohol Clin Exp Res 37(11):1910-1919. doi:10.1111/acer.12184 PMID:23763452 PMCID:PMC3775861
  • Thevenot PT, Saravia J, Jin N, Giaimo JD, Chustz RE, Mahne S, Kelley MA, Hebert VY, Dellinger B, Dugas TR, DeMayo FJ, Cormier SA. 2013. Radical-containing ultrafine particulate matter initiates epithelial-to-mesenchymal transitions in airway epithelial cells. Am J Respir Cell Mol Biol 48(2):188-197. doi:10.1165/rcmb.2012-0052OC PMID:23087054 PMCID:PMC3604062
  • Wang P, You D, Saravia J, Shen H, Cormier SA. 2013. Maternal exposure to combustion generated PM inhibits pulmonary Th1 maturation and concomitantly enhances postnatal asthma development in offspring. Part Fibre Toxicol 10:29. doi:10.1186/1743-8977-10-29 PMID:23856009 PMCID:PMC3717277
  • You D, Marr N, Saravia J, Shrestha B, Lee GI, Turvey SE, Brombacher F, Herbert DR, Cormier SA. 2013. IL-4R alpha on CD4(+) T cells plays a pathogenic role in respiratory syncytial virus reinfection in mice infected initially as neonates. J Leukoc Biol 93:933-942. doi:10.1189/jlb.1012498 PMID:23543769 PMCID:PMC3656337


  • Balakrishna S, Saravia J, Thevenot PT, Ahlert TA, Lominiki S, Dellinger B, Cormier SA. 2011. Environmentally persistent free radicals induce airway hyperresponsiveness in neonatal rat lungs. Part Fibre Toxicol 8(1):11. doi:10.1186/1743-8977-8-11 PMID:21388553 PMCID:PMC3061909 (Completed with ARRA Funds)
  • Lord K, Moll D, Lindsey JK, Mahne S, Raman G, Dugas TR, Cormier SA, Troxlair D, Lomnicki S, Dellinger B, Varner KJ. 2011. Environmentally persistent free radicals decrease cardiac function before and after ischemia/reperfusion injury in vivo. J Recept Signal Transduct Res 31(2):157-167. doi:10.3109/10799893.2011.555767 PMID:21385100 PMCID:PMC3152960 (Completed with ARRA Funds)
  • Wang P, Thevenot PT, Saravia J, Ahlert TA, Cormier SA. 2011. Radical-containing particles activate dendritic cells and enhance Th17 inflammation in a mouse model of asthma. Am J Respir Cell Mol Biol 45:977-983. doi:10.1165/rcmb.2011-0001OC PMID:21493781 PMCID:PMC3262685




  • Naura A, Hans C, Zerfaoui M, You D, Cormier SA, Oumouna M, Boulares A. 2008. Post-allergen challenge inhibition of poly(ADP-ribose) polymerase harbors therapeutic potential for treatment of allergic airway inflammation. Clinical and Experimental Allergy 38:839-846. doi:10.1111/j.1365-2222.2008.02943.x PMID:18261157 PMCID:PMC2740645
  • Wang K, You D, Balakrishna S, Ripple M, Ahlert TA, Fahmy B, Becnel D, Daly M, Subra W, McElduff JS, Lomax LG, Troxclair D, Cormier SA. 2008. Sediment from Hurricane Katrina: potential to produce pulmonary dysfunction in mice. Int J Clin Exp Pathol 1:130-144. PMID:19079667
  • You D, Ripple M, Balakrishna S, Troxclair D, Sandquist D, Ding L, Ahlert TA, Cormier SA. 2008. Inchoate CD8+ T cell responses in neonatal mice permit influenza-induced persistent pulmonary dysfunction. J Immunol 181(5):3486-3494. PMID:18714021 PMCID:PMC2659373
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