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Your Environment. Your Health.

Person Details: Shirley J. Gee

Superfund Research Program

Shirley J. Gee

University of California-Davis
Department of Entomology
96A Briggs Hall
One Shields Avenue
Davis, California 95616
Phone: 530-752-8465
Fax: 530-752-1537
Email: sjgee@ucdavis.edu

Projects

Research Briefs

Patents

Hazardous Waste Sites

Putah Creek Riparian Reserve

  • University of California-Davis: Immunoassays for Human and Environmental Health Monitoring

Publications

2020

  • He J, Ma S, Wu S, Xu J, Tian J, Li J, Gee SJ, Hammock BD, Li QX, Xu T. 2020. Construction of immunomagnetic particles with high stability in stringent conditions by site-directed immobilization of multivalent nanobodies onto bacterial magnetic particles for the environmental detection of tetrabromobisphenol-a. Anal Chem 92:1114-1121. doi:10.1021/acs.analchem.9b04177 PMID:31763820

2019

  • He J, Tao X, Wang K, Ding G, Li J, Li QX, Gee SJ, Hammock BD, Xu T. 2019. One-step immunoassay for the insecticide carbaryl using a chicken single-chain variable fragment (scFv) fused to alkaline phosphatase. Anal Biochem 572:9-15. doi:10.1016/j.ab.2019.02.022 PMID:30831096
  • Hongsibsong S, Prapamontol T, Dong J, Bever C, Xu Z, Gee SJ, Hammock BD. 2019. Exposure of consumers and farmers to organophosphate and synthetic pyrethroid insecticides in Northern Thailand. J Verbrauch Lebensm 14(1):17-23. doi:10.1007/s00003-019-01207-7
  • Liu Z, Wang K, Wang Z, Ding G, Hao X, Li QX, Li J, Gee SJ, Hammock BD, Xu T. 2019. Development of an immunoassay for the detection of carbaryl in cereals based on a camelid variable heavy-chain antibody domain. Journal of the Science of Food and Agriculture 99(9):4383-4390. doi:10.1002/jsfa.9672 PMID:30851058 PMCID:PMC7061733
  • Vasylieva N, Kitamura S, Dong J, Barnych B, Hvorecny KL, Madden DR, Gee SJ, Wolan DW, Morisseau C, Hammock BD. 2019. Nanobody-based binding assay for the discovery of potent inhibitors of CFTR inhibitory factor (Cif). Anal Chim Acta 1057:106-113. doi:10.1016/j.aca.2018.12.060 PMID:30832908 PMCID:PMC6426448
  • Wang K, Liu Z, Ding G, Li J, Vasylieva N, Li QX, Li D, Gee SJ, Hammock BD, Xu T. 2019. Development of a one-step immunoassay for triazophos using camel single-domain antibody-alkaline phosphatase fusion protein. Anal Bioanal Chem 411(6):1287-1295. doi:10.1007/s00216-018-01563-7
  • Wang K, Vasylieva N, Wan D, Eads DA, Yang J, Tretten T, Barnych B, Li J, Li QX, Gee SJ, Hammock BD, Xu T. 2019. Quantitative detection of fipronil and fipronil-sulfone in sera of black-tailed prairie dogs and rats after oral exposure to fipronil by camel single-domain antibody-based immunoassays. Anal Chem 91:1532-1540. doi:10.1021/acs.analchem.8b04653

2018

  • He J, Tian J, Xu J, Wang K, Li J, Gee SJ, Hammock BD, Li QX, Xu T. 2018. Strong and oriented conjugation of nanobodies onto magnetosomes for the development of a rapid immunomagnetic assay for the environmental detection of tetrabromobisphenol-A. Anal Bioanal Chem 410(25):6633-6642. doi:10.1007/s00216-018-1270-9 PMID:30066195

2017

  • Cui X, Vasylieva N, Wu P, Barnych B, Yang J, Shen D, He Q, Gee SJ, Zhao S, Hammock BD. 2017. Development of an indirect competitive enzyme-linked immunosorbent assay for glycocholic acid based on chicken single-chain variable fragment antibodies. Anal Chem 89:11091-11097. doi:10.1021/acs.analchem.7b03190 PMID:28942640
  • Li D, Cui Y, Morisseau C, Gee SJ, Bever C, Liu X, Wu J, Hammock BD, Ying Y. 2017. Nanobody based immunoassay for human soluble epoxide hydrolase detection using Polymeric Horseradish Peroxidase (PolyHRP) for signal enhancement: The rediscovery of PolyHRP?. Anal Chem 89(11):6248-6256. doi:10.1021/acs.analchem.7b01247 PMID:28460522 PMCID:PMC5611449
  • Liu X, Tang Z, Duan Z, He Z, Shu M, Wang X, Gee SJ, Hammock BD, Xu Y. 2017. Nanobody-based enzyme immunoassay for ochratoxin A in cereal with high resistance to matrix interference. Talanta 164:154-158. doi:10.1016/j.talanta.2016.11.039 PMID:28107910 PMCID:PMC5862147
  • Vasylieva N, Barnych B, Rand A, Inceoglu B, Gee SJ, Hammock BD. 2017. Sensitive immunoassay for detection and quantification of the neurotoxin, tetramethylenedisulfotetramine. Anal Chem 89(10):5612-5619. doi:10.1021/acs.analchem.7b00846 PMID:28398746
  • Vasylieva N, Barnych B, Wan D, El-Sheikh EA, Nguyen HM, Wulff H, McMahen R, Strynar M, Gee SJ, Hammock BD. 2017. Hydroxy-fipronil is a new urinary biomarker of exposure to fipronil. Environ Int 103:91-98. doi:10.1016/j.envint.2017.03.012 PMID:28343720 PMCID:PMC5432128
  • Wagner SD, Kurobe T, Hammock BG, Lam CH, Wu G, Vasylieva N, Gee SJ, Hammock BD, Teh SJ. 2017. Developmental effects of fipronil on Japanese Medaka (Oryzias latipes) embryos. Chemosphere 166:511-520. doi:10.1016/j.chemosphere.2016.09.069 PMID:27710886
  • Xu Z, Li Y, Sun Y, Beier RC, Lei H, Gee SJ, Hammock BD, Shen Y, Yang J, Wang H. 2017. Immunochemical techniques for multianalyte analysis of chemical residues in food and the environment: a review. Trends in Analytical Chemistry 88:25-40. doi:10.1016/j.trac.2016.12.010

2016

2015

  • Cui Y, Li D, Morisseau C, Dong J, Yang J, Wan D, Rossotti MA, Gee SJ, Gonzalez-Sapienza GG, Hammock BD. 2015. Heavy chain single-domain antibodies to detect native human soluble epoxide hydrolase. Anal Bioanal Chem 407(24):7275-7283. doi:10.1007/s00216-015-8889-6 PMID:26229025 PMCID:PMC4573264
  • Hua X, Zhou L, Feng L, Ding Y, Shi H, Wang L, Gee SJ, Hammock BD, Wang M. 2015. Competitive and noncompetitive phage immunoassays for the determination of benzothiostrobin. Anal Chim Acta 890:150-156. doi:10.1016/j.aca.2015.07.056 PMID:26347177 PMCID:PMC4791039
  • Liu X, Xu Y, Wan D, Xiong Y, He Z, Wang X, Gee SJ, Ryu D, Hammock BD. 2015. Development of a nanobody-alkaline phosphatase fusion protein and its application in a highly sensitive direct competitive fluorescence enzyme immunoassay for detection of ochratoxin A in cereal. Anal Chem 87(2):1387-1394. doi:10.1021/ac504305z PMID:25531426 PMCID:PMC4476795
  • Ranganathan A, Gee SJ, Hammock BD. 2015. An immunoassay for the detection of triclosan-O-glucuronide, a primary human urinary metabolite of triclosan. Anal Bioanal Chem 407(24):7263-7273. doi:10.1007/s00216-015-8918-5 PMID:26255293 PMCID:PMC4580343
  • Rossotti MA, Pirez M, Gonzalez-Techera A, Cui Y, Bever C, Lee KS, Morisseau C, Leizagoyen C, Gee SJ, Hammock BD, Gonzalez-Sapienza GG. 2015. Method for sorting and pairwise selection of nanobodies for the development of highly sensitive sandwich immunoassays. Anal Chem 87(23):11907-11914. doi:10.1021/acs.analchem.5b03561 PMID:26544909 PMCID:PMC4666776
  • Vasylieva N, Ahn K, Barnych B, Gee SJ, Hammock BD. 2015. Development of an immunoassay for the detection of the phenylpyrazole insecticide fipronil. Environ Sci Technol 49(16):10038-10047. doi:10.1021/acs.est.5b01005 PMID:26196357 PMCID:PMC4605820
  • Wang J, Majkova Z, Bever C, Yang J, Gee SJ, Li J, Xu T, Hammock BD. 2015. One-step immunoassay for tetrabromobisphenol a using a camelid single domain antibody-alkaline phosphatase fusion protein. Anal Chem 87(9):4741-4748. doi:10.1021/ac504735p PMID:25849972 PMCID:PMC4476793

2014

  • Bever C, Majkova Z, Radhakrishnan R, Suni II, McCoy MR, Wang Y, Dechant JE, Gee SJ, Hammock BD. 2014. Development and utilization of camelid VHH antibodies from alpaca for 2,2',4,4'-tetrabrominated diphenyl ether detection. Anal Chem 86(15):7875-7882. doi:10.1021/ac501807j PMID:25005746 PMCID:PMC4144723
  • Dong J, Xu C, Wang H, Xiao Z, Gee SJ, Li Z, Wang F, Wu W, Shen Y, Yang J, Sun Y, Hammock BD. 2014. Enhanced sensitive immunoassay: noncompetitive phage anti-immune complex assay for the determination of malachite green and leucomalachite green. J Agric Food Chem 62(34):8752-8758. doi:10.1021/jf5019824 PMID:25077381 PMCID:PMC4150606
  • Hua X, Yin W, Shi H, Li M, Wang Y, Wang H, Ye Y, Kim H, Gee SJ, Wang M, Liu F, Hammock BD. 2014. Development of phage immuno-loop-mediated isothermal amplification assays for organophosphorus pesticides in agro-products. Anal Chem 86(16):8441-8447. doi:10.1021/ac5020657 PMID:25135320 PMCID:PMC4139188
  • Liu X, Xu Y, Xiong Y, Tu Z, Li Y, He Z, Qiu Y, Fu J, Gee SJ, Hammock BD. 2014. VHH phage-based competitive real-time immuno-polymerase chain reaction for ultrasensitive detection of ochratoxin A in cereal. Anal Chem 86(15):7471-7477. doi:10.1021/ac501202d PMID:24992514 PMCID:PMC4306448
  • Thiphom S, Prapamontol T, Chantara S, Mangklabruks A, Suphavilai C, Ahn K, Gee SJ, Hammock BD. 2014. Determination of the pyrethroid insecticide metabolite 3-PBA in plasma and urine samples from farmer and consumer groups in northern Thailand. J Environ Sci Health B 49(1):15-22. doi:10.1080/03601234.2013.836862 PMID:24138464 PMCID:PMC4020914
  • Trunnelle KJ, Bennett DH, Ahn K, Schenker MB, Tancredi DJ, Gee SJ, Stoecklin-Marois MT, Hammock BD. 2014. Concentrations of the urinary pyrethroid metabolite 3-phenoxybenzoic acid in farm worker families in the MICASA study. Environ Res 131:153-159. doi:10.1016/j.envres.2014.03.003 PMID:24721133 PMCID:PMC4152318
  • Wang J, Bever C, Majkova Z, Dechant JE, Yang J, Gee SJ, Xu T, Hammock BD. 2014. Heterologous antigen selection of camelid heavy chain single domain antibodies against tetrabromobisphenol A. Anal Chem 86(16):8296-8302. doi:10.1021/ac5017437 PMID:25068372 PMCID:PMC4139172

2013

  • Han J, Kim H, Sudheendra L, Gee SJ, Hammock BD, Kennedy IM. 2013. Photonic crystal lab-on-a-chip for detecting staphylococcal entertoxin B at low attomolar concentration. Anal Chem 85(6):3104-3109. doi:10.1021/ac303016h PMID:23418954 PMCID:PMC3608201
  • Han J, Kim H, Sudheendra L, Hass EA, Gee SJ, Hammock BD, Kennedy IM. 2013. Electrophoretic build-up of multi nanoparticle array for a highly sensitive immunoassay. Biosens Bioelectron 41:302-308. doi:10.1016/j.bios.2012.08.042 PMID:23021853 PMCID:PMC3525773
  • Ranganathan A, Paradise GA, Hansen CA, McCoy MR, Gee SJ, Zhong P, Chang D, Hammock BD. 2013. Indirect homologous competitive enzyme-linked immunosorbent assay for the detection of a class of glycosylated dihydrochalcones. J Agric Food Chem 61(28):6964-6970. doi:10.1021/jf401302y PMID:23767873 PMCID:PMC3723731
  • Trunnelle KJ, Bennett DH, Tancredi DJ, Gee SJ, Stoecklin-Marois MT, Hennessy-Burt TE, Hammock BD, Schenker MB. 2013. Pyrethroids in house dust from the homes of farm worker families in the MICASA study. Environ Int 61:57-63. doi:10.1016/j.envint.2013.09.007 PMID:24096042 PMCID:PMC4059492
  • Wang Y, Li P, Majkova Z, Bever C, Kim H, Zhang Q, Dechant JE, Gee SJ, Hammock BD. 2013. Isolation of alpaca anti-idiotypic heavy-chain single-domain antibody for the aflatoxin immunoassay. Anal Chem 85(17):8298-8303. doi:10.1021/ac4015885 PMID:23965250 PMCID:PMC3787825
  • Wang Y, Wang H, Li P, Zhang Q, Kim H, Gee SJ, Hammock BD. 2013. Correction to: Phage- displayed peptide that mimics aflatoxins and its application in immunoassay. J Agric Food Chem 61(16):3994. doi:10.1021/jf401235p
  • Wang Y, Wang H, Li P, Zhang Q, Kim H, Gee SJ, Hammock BD. 2013. Phage-displayed peptide that mimics aflatoxins and its application in immunoassay. J Agric Food Chem 61(10):2426–2433. doi:10.1021/jf4004048 PMID:23394544 PMCID:PMC3830680

2012

  • Ahn K, Kasagami T, Tsai H, Schebb N, Ogunyoku TA, Gee SJ, Young TM, Hammock BD. 2012. An immunoassay to evaluate human/environmental exposure to the antimicrobial triclocarban. Environ Sci Technol 46:374-381. doi:10.1021/es202494d PMID:22077920 PMCID:PMC3258304 (Completed with ARRA Funds)
  • Han J, Sudheendra L, Kim H, Gee SJ, Hammock BD, Kennedy IM. 2012. Ultrasensitive on-chip immunoassays with a nanoparticle-assembled photonic crystal. ACS Nano 6(10):8570-8582. doi:10.1021/nn301656c PMID:22957818 PMCID:PMC3479307
  • Kim H, Majkova Z, Dechant JE, Gee SJ, Tabares-da Rosa S, Gonzalez-Sapienza GG, Hammock BD, McCoy MR. 2012. Isolation of alpaca anti-hapten heavy chain single domain antibodies for development of sensitive immunoassay. Anal Chem 84(2):1165-1171. doi:10.1021/ac2030255 PMID:22148739 PMCID:PMC3264785
  • Kim H, McCoy MR, Majkova Z, Dechant JE, Gee SJ, Tabares-da Rosa S, Gonzalez-Sapienza GG, Hammock BD. 2012. Correction to isolation of alpaca antihapten heavy chain single domain antibodies for development of sensitive immunioassay. Anal Chem 84(15):6919–6919. doi:10.1021/ac301927h PMID:22830304 PMCID:PMC3460544
  • McCoy MR, Yang Z, Fu X, Ahn K, Gee SJ, Bom DC, Zhong P, Chang D, Hammock BD. 2012. Monitoring of total type II pyrethroid pesticides in citrus oils and water by converting to a common product 3-phenoxybenzoic acid. J Agric Food Chem 60:5065-5070. doi:10.1021/jf2051653 PMID:22486225 PMCID:PMC3412423
  • Schebb N, Ahn K, Dong H, Gee SJ, Hammock BD. 2012. Whole blood is the sample matrix of choice for monitoring systemic triclocarbon levels. Chemosphere 87(7):825-827. doi:10.1016/j.chemosphere.2011.12.077 PMID:22273184 PMCID:PMC3538789 (Completed with ARRA Funds)
  • Thiphom S, Prapamontol T, Chantara S, Mangklabruks A, Suphavilai C, Ahn K, Gee SJ, Hammock BD. 2012. An enzyme-linked immunosorbent assay for detecting 3-phenoxybenzoic acid in plasma and its application to farmers and consumers. Analytical Methods 4:3772-3778. doi:10.1039/c2ay25642h PMID:23667388 PMCID:PMC3646417

2011

  • Ahn K, Gee SJ, Aronov PA, Vega H, Krieger RI, Hammock BD, Kim H. 2011. Immunochemical analysis of 3-phenoxybenzoic acid, a biomarker of forestry worker exposure to pyrethroid insecticides. Anal Bioanal Chem 401(4):1285-1293. doi:10.1007/s00216-011-5184-z PMID:21717113 PMCID:PMC3848323
  • Ahn K, Kim H, McCoy MR, Gee SJ, Hammock BD. 2011. Immunoassays and biosensors for monitoring environmental and human exposure to pyrethroid insecticides. J Agric Food Chem 59(7):2792-2802. doi:10.1021/jf1033569 PMID:21105656 PMCID:PMC3070843
  • Gee SJ, Gonazlez-Sapienza GG, Hammock BD, Kim H, McCoy MR. 2011. Noncompetitive phage anti-immunocomplex real-time polymerase chain reaction for sensitive detection of small molecules. Anal Chem 83(1):246-253. doi:10.1021/ac102353z PMID:21141939 PMCID:PMC3031424
  • Schebb N, Inceoglu B, Ahn K, Morisseau C, Gee SJ, Hammock BD. 2011. Investigation of human exposure to triclocarban after showering and preliminary evaluation of its biological effects. Environ Sci Technol 45:3109-3115. doi:10.1021/es103650m PMID:21381656 PMCID:PMC3470465 (Completed with ARRA Funds)

2010

  • Garcia-Nieto E, Nichkova MJ, Yanez L, Costilla-Salazar R, Torres-Dosal A, Gee SJ, Hammock BD, Juarez-Santacruz L, Diaz-Barriga F. 2010. Assessment of dioxin-like soil contamination in Mexico by enzyme-linked immunosorbent assay. Arch Environ Contam Toxicol 58(4):918-926. doi:10.1007/s00244-009-9422-8 PMID:20091164 PMCID:PMC3033344
  • Kim H, Rossotti MA, Ahn K, Gonzalez-Sapienza GG, Gee SJ, Musker R, Hammock BD. 2010. Development of a noncompetitive phage anti-immunocomplex assay for brominated diphenyl ether 47. Anal Biochem 401(1):38-46. doi:10.1016/j.ab.2010.01.040 PMID:20152791 PMCID:PMC2861364

2009

  • Ahn K, Gee SJ, Tsai H, Bennett DH, Nishioka M, Blum A, Fishman E, Hammock BD. 2009. Immunoassay for monitoring environmental and human exposure to the polybrominated diphenyl ether BDE-47. Environ Sci Technol 43(20):7784-7790. doi:10.1021/es9009037 PMID:19921894 PMCID:PMC3528349
  • Kim HJ, Ahn K, Gonzalez-Techera A, Gonzalez-Sapienza GG, Gee SJ, Hammock BD. 2009. Magnetic bead-based phage anti-immunocomplex assay (PHAIA) for the detection of the urinary biomarker 3-phenoxybenzoic acid to assess human exposure to pyrethroid insecticides. Anal Biochem 386(1):45-52. doi:10.1016/j.ab.2008.12.003 PMID:19101498 PMCID:PMC2863013
  • Ma Z, Dosev D, Nichkova MJ, Dumas RK, Gee SJ, Hammock BD, Kennedy IM. 2009. Synthesis and characterization of multifunctional silica core-shell nanocomposites with magnetic and fluorescent functionalities. J Magn Magn Mater 321(10):1368-1371. doi:10.1016/j.jmmm.2009.02.040 PMID:20336173 PMCID:PMC2844650
  • Ma Z, Dosev D, Nichkova MJ, Gee SJ, Hammock BD, Kennedy IM. 2009. Synthesis and bio-functionalization of multifunctional magnetic Fe3O4@Y2O3:Eu nanocomposites. J Mater Chem 19:4695-4700. doi:10.1039/B901427F PMID:20357905 PMCID:PMC2847302
  • Nichkova MJ, Fu X, Yang Z, Zhong P, Sanborn JR, Chang D, Gee SJ, Hammock BD. 2009. Immunochemical screening of pesticides (simazine and cypermethrin) in orange oil. J Agric Food Chem 57(13):56735679. doi:10.1021/jf900652a PMID:19526986 PMCID:PMC3033343
  • Shen S, Zhang F, Zeng S, Tian Y, Chai X, Gee SJ, Hammock BD, Zheng J. 2009. Development of enantioselective polyclonal antibodies to detect styrene oxide protein adducts. Anal Chem 81(7):2668-2677. doi:10.1021/ac8023262 PMID:19245253 PMCID:PMC3463234

2008

  • Chen J, Ahn K, Gee NA, Ahmed MI, Duleba AJ, Zhao L, Gee SJ, Hammock BD, Lasley BL. 2008. Triclocarban enhances testosterone action: a new type of endocrine disruptor?. Endocrinology 149(3):1173-1179. doi:10.1210/en.2007-1057 PMID:18048496 PMCID:PMC2275366
  • Chen J, Ahn K, Zhao B, Denison MS, Lasley BL, Pessah IN, Kültz D, Chang DP, Gee SJ, Hammock BD, Cherednichenko G. 2008. In vitro biologic activities of the antimicrobials triclocarban, its analogs, and triclosan in bioassay screens: receptor-based bioassay screens. Environ Health Perspect 116:1203-1210. doi:10.1289/ehp.11200 PMID:18795164 PMCID:PMC2535623
  • Gonzalez-Techera A, Umpierrez-Failache M, Cardozo S, Obal G, Last JA, Gee SJ, Hammock BD, Gonzalez-Sapienza GG, Pritsch O. 2008. High-throughput method for ranking the affinity of peptide ligands selected from phage display libraries. Bioconjug Chem 19(5):993-1000. doi:10.1021/bc700279y PMID:18393454 PMCID:PMC2863005
  • Kim HJ, Gonzalez-Techera A, Gonzalez-Sapienza GG, Ahn K, Gee SJ, Hammock BD. 2008. Phage-borne peptidomimetics accelerate the development of polyclonal antibody-based heterologous immunoassays for the detection of pesticide metabolites. Environ Sci Technol 42(6):2047-53. doi:10.1021/es702219a PMID:18409635
  • Park E, Duarte Tagles H, Gee SJ, Hammock BD, Lee K, Schenker MB. 2008. Recruiting strategy and 24-hour biomonitoring of paraquat in agricultural workers. J Agromedicine 13(4):207-217. doi:10.1080/10599240802454528 PMID:19064412 PMCID:PMC2864554
  • Van Emon JM, Chuang J, Lordo RA, Schrock ME, Nichkova MJ, Gee SJ, Hammock BD. 2008. An enzyme-linked immunosorbent assay for the determination of dioxins in contaminated sediment and soil samples. Chemosphere 72(1):95-103. doi:10.1016/j.chemosphere.2008.01.012 PMID:18313102 PMCID:PMC2858573

2007

  • Ahn K, Lohstroh PN, Gee SJ, Gee NA, Lasley BL, Hammock BD. 2007. High-throughput automated luminescent magnetic particle-based immunoassay to monitor human exposure to pyrethroid insecticides. Anal Chem 79(23):8883-8890. doi:10.1021/ac070675l PMID:17983205
  • Chen J, Ahn K, Gee SJ, Gee NA, Hammock BD, Lasley BL. 2007. Antiandrogenic properties of parabens and other phenolic containing small molecules in personal care products. Toxicol Appl Pharmacol 221(3):278-284. doi:10.1016/j.taap.2007.03.015 PMID:17481686 PMCID:PMC1978490
  • Dosev D, Nichkova MJ, Dumas RK, Gee SJ, Hammock BD, Liu K, Kennedy IM. 2007. Magnetic/luminescent core/shell particles synthesized by spray pyrolysis and their application in immunoassays with internal standard. Nanotechnology 18(5):055102(6pp). PMID:18974844
  • Gonzalez-Techera A, Kim HJ, Gee SJ, Last JA, Hammock BD. 2007. Polyclonal antibody-based noncompetitive immunoassay for small analytes developed with short peptide loops isolated from phage libraries. Anal Chem 79(23):9191-9196. doi:10.1021/ac7016713 PMID:17973501 PMCID:PMC2556293
  • Kim H, Gee SJ, Li QX, Hammock BD. 2007. Noncompetitive Fluorescent Immunoassay for the Detection of the Human Urinary Biomarker 3-Phenoxybenzoic Acid with Bench Top Immunosensor KinExATM 3000. Chapter 11in: Rational Environmental Management of Agrochemicals: Risk Assessment, Monitoring, and Remedial Action. pp.171185.
  • Kim HJ, Ahn K, Ma S, Gee SJ, Hammock BD. 2007. Development of sensitive immunoassays for the detection of the glucuronide conjugate of 3-phenoxybenzyl alcohol, a putative human urinary biomarker for pyrethroid exposure. J Agric Food Chem 55(10):3750-7. PMID:17455946
  • Nichkova MJ, Dosev D, Davies AE, Gee SJ, Kennedy IM, Hammock BD. 2007. Multiplexed immunoassays for biomonitoring of exposure to agrochemicals using quantum dots as fluorescent reporters. Proc SPIE Int Soc Opt Eng 6448:644817-1. doi:10.1117/12.699231
  • Nichkova MJ, Dosev D, Davies AE, Gee SJ, Kennedy IM, Hammock BD. 2007. Quantum dots as reporters in multiplexed immunoassays for biomarkers of exposure to agrochemicals. Anal Lett 40(7):1423-1433. doi:10.1080/00032710701327088 PMID:19079795 PMCID:PMC2600528
  • Nichkova MJ, Dosev D, Gee SJ, Hammock BD, Kennedy IM. 2007. Multiplexed immunoassays for proteins using magnetic luminescent nanoparticles for internal calibration. Anal Biochem 369(a):34-40. PMID:17681270
  • Yuan W, Chung JS, Gee SJ, Hammock BD, Zheng J. 2007. Development of polyclonal antibodies for the detection of styrene oxide modified proteins. Chem Res Toxicol 20(2):316-321. doi:10.1021/tx600340c PMID:17266334 PMCID:PMC2565645

2006

  • Ahn K, Ma S, Tsai H, Gee SJ, Hammock BD. 2006. An immunoassay for a urinary metabolite as a biomarker of human exposure to the pyrethroid insecticide permethrin. Anal Bioanal Chem 384(3):713-722. PMID:16416099
  • Cummins CM, Koivunen ME, Stephanian A, Gee SJ, Hammock BD, Kennedy IM. 2006. Application of europium(III) chelate-dyed nanoparticle labels in a competitive atrazine fluoroimmunoassay on an ITO waveguide. Biosens Bioelectron 21(7):1077-1085. PMID:16368482
  • Huang H, Nishi K, Gee SJ, Hammock BD. 2006. Evaluation of chiral alpha-cyanoesters as general fluorescent substrates for screening enantioselective esterases. J Agric Food Chem 54(3):694-699. doi:10.1021/jf0526083 PMID:16448170 PMCID:PMC1444886
  • Koivunen ME, Dettmer K, Vermeulen R, Bakke B, Gee SJ, Hammock BD. 2006. Improved methods for urinary atrazine mercapturate analysis--assessment of an enzyme-linked immunosorbent assay (ELISA) and a novel liquid chromatography-mass spectrometry (LC-MS) method utilizing online solid phase extraction (SPE). Anal Chim Acta 572(2):180-189. doi:10.1016/j.aca.2006.05.037 PMID:17723476
  • Nichkova MJ, Dosev D, Perron R, Gee SJ, Hammock BD, Kennedy IM. 2006. Eu3+-doped Gd2O3 nanoparticles as reporters for optical detection and visualization of antibodies patterned by microcontact printing. Anal Bioanal Chem 384(3):631-637. PMID:16416096
  • Nording M, Nichkova MJ, Spinnel E, Persson Y, Gee SJ, Hammock BD, Haglund P. 2006. Rapid screening of dioxin-contaminated soil by accelerated solvent extraction/purification followed by immunochemical detection. Anal Bioanal Chem 385(2):357-366. PMID:16598456
  • Wheelock AM, Miller JL, Miller MJ, Phillips BM, Huntley SA, Gee SJ, Tjeerdema RS, Hammock BD. 2006. Use of carboxylesterase activity to remove pyrethroid-associated toxicity to Ceriodaphnia dubia and Hyalella azteca in toxicity identification evaluations. Environ Toxicol Chem 25(4):973-984. PMID:16629136 PMCID:PMC1456014

2005

  • Ahn K, Gee SJ, Kim HJ, Nichkova MJ, Hammock BD. 2005. Progress in the development of biosensors for environmental and human monitoring of agrochemicals. Proceedings of the American Chemical Society Pacifichem 966:138-154.
  • Huang H, Stok JE, Stoutamire DW, Gee SJ, Hammock BD. 2005. Development of optically pure pyrethroid-like fluorescent substrates for carboxylesterases. Chem Res Toxicol 18(3):516-527. doi:10.1021/tx049773h PMID:15777092
  • Koivunen ME, Gee SJ, Park E, Lee K, Schenker MB, Hammock BD. 2005. Application of an enzyme-linked immunosorbent assay for the analysis of paraquat in human-exposure samples. Arch Environ Contam Toxicol 48(2):184-190. doi:10.1007/s00244-003-0251-x PMID:15696345
  • Mak SK, Shan G, Lee H, Watanabe T, Stoutamire DW, Gee SJ, Hammock BD. 2005. Development of a class selective immunoassay for the type II pyrethroid insecticides. Anal Chim Acta 534:109-120.
  • Nichkova MJ, Dosev D, Gee SJ, Hammock BD, Kennedy IM. 2005. Microarray immunoassay for phenoxybenzoic acid using polymer encapsulated Eu:Gd2O3 nanoparticles as fluorescent labels. Anal Chem 77(21):6864-6873. doi:10.1021/ac050826p PMID:16255584
  • Wheelock CE, Miller JL, Miller MJ, Phillips BM, Gee SJ, Tjeerdema RS, Hammock BD. 2005. Influence of container adsorption upon observed pyrethroid toxicity to Ceriodaphnia dubia and Hyalella azteca. Aquat Toxicol 74(1):47-52. PMID:15951033

2004

  • Ahn K, Watanabe T, Gee SJ, Hammock BD. 2004. Hapten and antibody production for a sensitive immunoassay determinining a human urinary metabolite of the pyrethroid insecticide permethrin. J Agric Food Chem 52(15):4583-4594. PMID:15264887
  • Kennedy IM, Koivunen ME, Gee SJ, Cummins CM, Perron R, Dosev D, Hammock BD. 2004. Nanoscale fluoro-immuno assays with lanthanide oxide nanoparticles. Chapter 5593 in: Nanosensing: Materials and Devices (Proceedings of SPIE). SPIE Society of Photo-Optical Instrumentation Engineering, Bellingham, WA. pp.329-339.
  • Lee H, Shan G, Ahn K, Park E, Watanabe T, Gee SJ, Hammock BD. 2004. Development of an enzyme-linked Immunosorbent assay for the pyrethroid cypermethrin. J Agric Food Chem 52(2):1039-1043. PMID:14995094
  • Nichkova MJ, Park E, Koivunen ME, Kamita SG, Gee SJ, Chuang J, Van Emon JM, Hammock BD. 2004. Immunochemical determination of dioxins in environmental and biological samples. Talanta 63:1213-1223. PMID:18969550
  • Park E, Kim J, Gee SJ, Watanabe T, Ahn K, Hammock BD. 2004. Determination of pyrethroid residues in agricultural products by an enzyme-linked immunosorbent assay. J Agric Food Chem 52(18):5572-5576. PMID:15373394
  • Rufo C, Hammock BD, Gee SJ, Last JA, Gonzalez-Sapienza GG. 2004. Robust and sensitive monoclonal enzyme-linked immunosorbent assay for the herbicide molinate. J Agric Food Chem 52(2):182-187. PMID:14733492
  • Shan G, Huang H, Stoutamire DW, Gee SJ, Leng G, Hammock BD. 2004. A sensitive class specific immunoassay for the detection of pyrethroid metabolites in human urine. Chem Res Toxicol 17(2):218-225. PMID:14967009
  • Wheelock CE, Miller JL, Miller MJ, Gee SJ, Shan G, Hammock BD. 2004. Development of toxicity identification evaluation procedures for pyrethroid detection using esterase activity. Environ Toxicol Chem 23(11):2699-2708. PMID:15559286

2003

  • Kim Y, Cho YA, Lee H, Lee YT, Gee SJ, Hammock BD. 2003. Synthesis of haptens for immunoassay of organophosphorus pesticides and effect of heterology in hapten spacer arm length of immunoassay sensitivity. Anal Chim Acta 475(1-2):85-96.
  • Lee H, Watanabe T, Gee SJ, Hammock BD. 2003. Application of an enzyme-linked immunosorbent assay (ELISA) to determine deltamethrin residues in milk. Bull Environ Contam Toxicol 71(1):14-20. PMID:12945836
  • Lee JK, Ahn K, Stoutamire DW, Gee SJ, Hammock BD. 2003. Development of an enzyme-linked immunosorbent assay for the detection of the organophosphorus insecticide acephate. J Agric Food Chem 51(13):3695-3703. PMID:12797729

2002

  • Denison MS, Nagy SR, Ziccardi MH, Clark GC, Chu MD, Brown DJ, Shan G, Sugawara Y, Gee SJ, Sanborn JR, Hammock BD. 2002. Bioanalytical approaches for the detection of dioxin and related halogenated aromatic hydrocarbons. In: Biomarkers of Environmentally Associated Disease: Technologies, Concepts, and Perspectives. CRC Press Company, Boca Raton, FL. pp.483-494.
  • Lee H, Shan G, Watanabe T, Stoutamire DW, Gee SJ, Hammock BD. 2002. Enzyme-linked immunosorbent assay for the pyrethroid deltamethrin. J Agric Food Chem 50(20):5526-5532. PMID:12236674
  • Shelver WL, Shan G, Gee SJ, Stanker LH, Hammock BD. 2002. Comparison of immunoaffinity column recovery patterns of polychlorinated dibenzo-p-dioxins/polychlorinated dibenzofurans on columns generated with different monoclonal antibody clones and polyclonal antibodies. Anal Chim Acta 457:199-209.
  • Zurek G, Gee SJ, Hammock BD. 2002. Development of an enzyme immunoassay for linoleic acid diols in urine. Anal Chim Acta 466(2):247-256.

2001

  • Buchholz BA, Vogel JS, Gilman DS, Gee SJ, Hammock BD, Hui X, Wester RC, Maibach HI. 2001. Determining an occupational dermal exposure biomarker for atrazine through measurement of metabolites in human urine by HPLC-accelerator mass spectrometry. In: Toxicology of Skin. Taylor & Francis, Philadelphia, PA. pp.145-157.
  • Matveeva EG, Gribkova EV, Sanborn JR, Gee SJ, Hammock BD, Savitsky AP. 2001. Development of a homogeneous phosphorescent immunoassay for the detection of polychlorinated dibenzo-p-dioxins. Anal Lett 34(13):2311-2320.
  • Matveeva EG, Shan G, Kennedy IM, Gee SJ, Hammock BD. 2001. Homogeneous fluoroimmunoassay of a pyrethroid metabolite in urine. Anal Chim Acta 444:103-117.
  • Shan G, Leeman WR, Gee SJ, Sanborn JR, Jones AD, Chang DP, Hammock BD. 2001. Highly sensitive dioxin immunoassay and its application to soil and biota samples. Anal Chim Acta 444:169-178.
  • Staimer N, Gee SJ, Hammock BD. 2001. Development of a class-selective enzyme immunoassay for urinary phenolic glucuronides. Anal Chim Acta 444:27-36.
  • Staimer N, Gee SJ, Hammock BD. 2001. Development of a sensitive enzyme immunoassay for the detection of phenyl-b-D-thioglucuronide in human urine. Fresenius J Anal Chem 369(3-4):273-279. PMID:11293704
  • Watanabe T, Shan G, Stoutamire DW, Gee SJ, Hammock BD. 2001. Development of a class-specific immunoassay for the type I pyrethroid insecticides. Anal Chim Acta 444:119-129.

2000

  • Lohse C, Jaeger LL, Staimer N, Sanborn JR, Jones AD, Lango J, Gee SJ, Hammock BD. 2000. Development of a class selective enzyme-linked immunosorbent assay for mercapturic acids in human urine. J Agric Food Chem 48(12):5913-5923. PMID:11312767
  • Shan G, Huang W, Gee SJ, Buchholz BA, Vogel JS, Hammock BD. 2000. Isotope-labeled immunoassays without radiation waste. Proc Natl Acad Sci U S A 97(6):2445-2449. PMID:10706612
  • Shan G, Leeman WR, Stoutamire DW, Gee SJ, Chang DP, Hammock BD. 2000. Enzyme-linked immunosorbent assay for the pyrethroid permethrin. J Agric Food Chem 48(9):4032-4040. PMID:10995309
  • Shan G, Sanborn JR, Gilman DS, Nagy SR, Gee SJ, Stoutamire DW, Mercer RS, Jones AD, Stanker LH, Denison MS, Hammock BD. 2000. Surrogates for dioxin analyses: analytical, ELISA and toxicological aspects. Organohalogen Compounds 45:188-191.

1999

  • Buchholz BA, Fultz E, Haack KW, Vogel JS, Gilman DS, Gee SJ, Hammock BD, Hui X, Wester RC, Maibach HI. 1999. HPLC-accelerator MS measurement of atrazine metabolites in human urine after dermal exposure. Anal Chem 71(16):3519-3525. PMID:10464479
  • Shan G, Stoutamire DW, Gee SJ, Wengatz I, Hammock BD. 1999. Development of an immunoassay for the pyrethroid insecticide esfenvalerate. J Agric Food Chem 47(5):2145-2155. PMID:10552511
  • Shan G, Wengatz I, Stoutamire DW, Gee SJ, Hammock BD. 1999. An enzyme-linked immunosorbent assay for the detection of esfenvalerate metabolites in human urine. Chem Res Toxicol 12(11):1033-1041. PMID:10563828
  • Yazynina EV, Zherdev AV, Dzantiev BB, Izumrudov VA, Gee SJ, Hammock BD. 1999. Immunoassay techniques for detection of the herbicide simazine based on use of oppositely charged water-soluble polyelectrolytes. Anal Chem 71(16):3538-3543. PMID:10464482
  • Yazynina EV, Zherdev AV, Dzantiev BB, Izumrudov VA, Gee SJ, Hammock BD. 1999. Microplate immunoassay technique using polyelectrolyte carriers: kinetic studies and application to detection of the herbicide atrazine. Anal Chim Acta 399(1-2):151-160.

1998

  • Gilman DS, Gee SJ, Hammock BD, Vogel JS, Haack KW, Buchholz BA, Freeman SP, Wester RC, Hui X, Maibach HI. 1998. Analytical performance of accelerator mass spectrometry and liquid scintillation counting for detection of 14C-labeled atrazine metabolites in human urine. Anal Chem 70(16):3463-3469. PMID:9726169
  • Harris AS, Wengatz I, Wortberg M, Kreissig SB, Gee SJ, Hammock BD. 1998. Development and application of immunoassays for biological and environmental monitoring. In: Effects of Multiple Impacts on Ecosystems. Lewis Publishers, Chelsea, MI. pp.135-153.
  • Marco M, Gee SJ, Hammock BD. 1998. Determination of 1-naphthol in well water samples by ELISA. In: Current Protocols in Field Analytical Chemistry. (V. Lopez-Avila, ed.) John Wiley & Sons, New York, NY. pp.2C.9.1-2C.9.11.
  • Marco M, Gee SJ, Hammock BD. 1998. Determination of carbaryl in well water samples by ELISA. In: Current Protocols in Field Analytical Chemistry. (V. Lopez-Avila, ed.) John Wiley & Sons, New York, NY. pp.2C8.1-2C8.15.
  • Reimer GJ, Gee SJ, Hammock BD. 1998. Comparison of a time-resolved fluorescence immunoassay and an enzyme-linked immunosorbent assay for the analysis of atrazine in water. J Agric Food Chem 46(8):3353-3358.
  • Sanborn JR, Gee SJ, Gilman DS, Sugawara Y, Jones AD, Rogers JM, Szurdoki F, Stanker LH, Stoutamire DW, Hammock BD. 1998. Hapten synthesis and antibody development for polychlorinated dibenzo-p-dioxin immunoassays. J Agric Food Chem 46:2407-2416.
  • Sugawara Y, Gee SJ, Sanborn JR, Gilman DS, Hammock BD. 1998. Development of a highly sensitive enzyme-linked immunosorbent assay based on polyclonal antibodies for the detection of polychlorinated dibenzo-p-dioxins. Anal Chem 70(6):1092-1099. PMID:9530001
  • Wengatz I, Stoutamire DW, Gee SJ, Hammock BD. 1998. Development of an enzymelinked immunosorbent assay for the detection of the pyrethroid insecticide fenpropathrin. J Agric Food Chem 46(6):2211-2221.

1997

  • Kido H, Goodrow MH, Griffeth V, Lucas AD, Gee SJ, Hammock BD. 1997. Development of an enzyme-linked immunosorbent assay for the detection of hydroxytriazines. J Agric Food Chem 45(2):414-424.
  • Schutz S, Wengatz I, Goodrow MH, Gee SJ, Hummel HE, Hammock BD. 1997. Development of an enzyme-linked-immunosorbent assay for azadirachtins. J Agric Food Chem 45(6):2363-2368.

1996

  • Linde CD, Gee SJ, Goh KS, Hsu JC, Hammock BD, Barry TA, Weaver DJ. 1996. Regulatory application of ELISA: compliance monitoring of bromacil in soil. Bull Environ Contam Toxicol 57(2):264-269. PMID:8661908
  • Szurdoki F, Jaeger LL, Harris AS, Kido H, Wengatz I, Goodrow MH, Szekacs A, Wortberg M, Zheng J, Stoutamire DW, Sanborn JR, Gilman DS, Jones AD, Gee SJ, Choudary P, Hammock BD. 1996. Rapid assays for environmental and biological monitoring. J Environ Sci Health B 31(3):451-458. PMID:8642182
  • Wengatz I, Harris AS, Gilman DS, Wortberg M, Kido H, Szurdoki F, Goodrow MH, Jaeger LL, Stoutamire DW, Sanborn JR, Gee SJ, Hammock BD. 1996. Recent developments in immunoassays and related methods for the detection of xenobiotics. In: Environmental Immunochemical Methods, Perspectives and Applications. ACS Symposium Series No. 646, American Chemical Society, Washington, DC. pp.110-126.
  • Wortberg M, Goodrow MH, Gee SJ, Hammock BD. 1996. Immunoassay for simazine and atrazine with low cross-reactivity for propazine. J Agric Food Chem 44(8):2210-2219.
  • Wortberg M, Jones G, Kreissig SB, Rocke DM, Gee SJ, Hammock BD. 1996. An approach to the construction of an immunoarray for differentiating and quantitating cross reacting analytes. Anal Chim Acta 319(3):291-303.

1995

  • Gee SJ, Hammock BD, Skerritt JH. 1995. Diagnostics for plant agrochemicals--a meeting of chemistry and immunoassay. In: New Diagnostics in Crop Sciences. CAB International, Oxon, United Kingdom. pp.243-276.
  • Gee SJ, Lucas AD, Hammock BD. 1995. Using immunochemical methods to analyze for biomarkers of exposure. In: Methods of Pesticide Exposure Assessment. Plenum Press, NY. pp.143-155.
  • Gee SJ, Lucas AD, Hammock BD. 1995. Using immunochemical methods to analyze for biomarkers of exposure. In: Proceedings of the NATO (North Atlantic Treaty Organisation) Workshop on Methods of Pesticide Exposure Assessment. Ottawa, Canada.
  • Goodrow MH, Sanborn JR, Stoutamire DW, Gee SJ, Hammock BD. 1995. Strategies for immunoassay hapten design. In: Immunoanalysis of Agrochemicals: Emerging Technologies (ACS Symposium Series 586). American Chemical Society, Washington, DC. pp.119-139.
  • Hammock BD, Gee SJ. 1995. Impact of emerging technologies on immunochemical methods for environmental analysis. In: Immunoanalysis of Agrochemicals: Emerging Technologies (ACS Symposium Series 586). American Chemical Society, Washington, DC. pp.1-19.
  • Harris AS, Lucas AD, Kramer PM, Marco M, Gee SJ, Hammock BD. 1995. Use of immunoassay for the detection of urinary biomarkers of exposure. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.217-235.
  • Lucas AD, Gee SJ, Hammock BD, Seiber JN. 1995. Integration of immunochemical methods with other analytical techniques for pesticide residue determination. J AOAC Int 78(3):585-591. PMID:7756872
  • Schneider P, Gee SJ, Kreissig SB, Harris AS, Kramer PM, Marco M, Lucas AD, Hammock BD. 1995. Troubleshooting during the development and use of immunoassays for environmental monitoring. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.103-122.
  • Sundaram KM, Sundaram A, Gee SJ, Harrison RO, Hammock BD. 1995. Enzyme-linked immunosorb and assay for quantification of Bacillus thuringiensis var. kurstaki crystaline protein in commerical formulations, in relation to total protein content and insecticidal activity. In: Pesticide Formulations and Applicaiton Systems, 14th Volume. American Society for Testing and Materials, Philadelphia, PA.
  • Wengatz I, Szurdoki F, Swamy AR, Evans L, Patonay G, Stimman E, Delwiche M, Stoutamire DW, Gee SJ, Hammock BD. 1995. Immunoassays for pesticide monitoring. SPIE Proceedings, San Jose, CA 408-416.
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