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Person Details: Kirby C. Donnelly

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Superfund Research Program

Kirby C. Donnelly

Texas A&M University
Environmental & Occupational Health
The School of Rural Public Health Bldg.
1266 TAMU
College Station, Texas 77843-1266

Projects

Research Briefs

Hazardous Waste Sites

Abandoned Refinery (PNAs and lead)

  • Invalid project

Atlantic Wood Industries

  • Invalid project

Auto recycling (PCBs, metals)

  • Invalid project

Baldwin Waste Oil (petroleum/pesticides)

  • Invalid project

Burlington Northern (Somers Plant)

  • Invalid project

Cape Fear Wood Preserving

  • Invalid project

Coal Creek (PCBs)

  • Invalid project

Coal gasification

  • Invalid project

Coal Tar

  • Invalid project

Dept. of Energy (explosives)

  • Invalid project

Drake Chemical (pesticides)

  • Invalid project

Drum Storage Area (pesticides)

  • Invalid project

Du Quoin Gas Plant

  • Invalid project

Eagle Harbor

  • Invalid project

Harbor Island (mixed industrial)

  • Invalid project

Iacavazzi Landfill (mixed industrial)

  • Invalid project

Industrial (PCBs)

  • Invalid project

Jennison-Wright Corporation

  • Invalid project

Joliet Army Ammunition Plant (Manufacturing Area)

  • Invalid project

Lake Union

  • Invalid project
  • Invalid project

Landfill (PCBs)

  • Invalid project

Landfill (pesticides)

  • Invalid project

Libby Groundwater

  • Invalid project
  • Invalid project

Marine dock (PCBs, PNAs, metals)

  • Invalid project

Marine Facility (PNAs)

  • Invalid project

marine sites 2

  • Invalid project

McBAy Oil (petroleum)

  • Invalid project

Metals, PNAs, PCBs

  • Invalid project

Mixed Industrial

  • Invalid project

Montana Pole And Treating

  • Invalid project

Municipal

  • Invalid project

Munitions 1

  • Invalid project

Munitions 2

  • Invalid project

Oil Reclamation (PNAs)

  • Invalid project

Pesticide Disposal

  • Invalid project

Pesticides

  • Invalid project

Savanah Army Depot (munitions)

  • Invalid project

Solvent recovery (PAHs and pesticides)

  • Invalid project

Solvent Recovery Service (petroleum)

  • Invalid project

Solvents and metals

  • Invalid project

State Marine (petroleum)

  • Invalid project

Texarkana Wood Preserving Co.

  • Invalid project

Wood Preserving (PNAs and PCP) 1

  • Invalid project

Wood Preserving (PNAs and PCP) 2

  • Invalid project

Wood Preserving (PNAs)

  • Invalid project

Wood Preserving 1

  • Invalid project

Wood Preserving 2

  • Invalid project

Wood Preserving 3

  • Invalid project

Wood Preserving 4

  • Invalid project

Wood Preserving 5

  • Invalid project

Wood Preserving 6

  • Invalid project

Publications

2015

  • Phillips TD, Richardson MB, Cheng YL, He L, McDonald TJ, Cizmas LH, Safe SH, Donnelly KC, Wang F, Moorthy B, Zhou GD. 2015. Mechanistic relationships between hepatic genotoxicity and carcinogenicity in male B6C3F1 mice treated with polycyclic aromatic hydrocarbon mixtures. Arch Toxicol 89(6):967-977. doi:10.1007/s00204-014-1285-8 PMID:24888377 PMCID:PMC4254891

2014

  • dela Cruz AL, Cook RL, Dellinger B, Lomnicki S, Donnelly KC, Kelley MA, Cosgriff D. 2014. Assessment of environmentally persistent free radicals in soils and sediments from three Superfund sites. Environ Sci Process Impacts 16(1):44-52. doi:10.1039/c3em00428g PMID:24244947 PMCID:PMC3907510

2012

  • Theodorakis CW, Bickham JW, Donnelly KC, McDonald TJ, Willink PW. 2012. DNA damage in cichlids from an oil production facility in Guatemala. Ecotoxicology 21:496-511. doi:10.1007/s10646-011-0811-1 PMID:22080433

2011

2010

  • Browne E, Kelley MA, Zhou GD, He L, McDonald TJ, Wang S, Duncan B, Meador J, Donnelly KC, Gallagher EP. 2010. In situ biomonitoring of juvenile Chinook salmon (Onchorhynchus tshawytscha) using biomarkers of chemical exposures and effects in a partially remediated urbanized waterway of the Puget Sound, WA. Environ Res 110(7):675-683. doi:10.1016/j.envres.2010.06.007 PMID:20619832 PMCID:PMC3321373

2008

  • Barbee GC, Barich J, Duncan B, Bickham JW, Matson CW, Hintze CJ, Autenrieth RL, Zhou GD, McDonald TJ, Cizmas LH, Norton D, Donnelly KC. 2008. In situ biomonitoring of PAH-contaminated sediments using juvenile coho salmon (Oncorhynchus kisutch). Ecotoxicol Environ Saf 71(2):454-464. doi:10.1016/j.ecoenv.2008.01.001 PMID:18304636
  • Naspinski C, Lingenfelter R, Cizmas LH, Naufal Z, He L, Islamzadeh A, Li Z, Li Z, McDonald TJ, Donnelly KC. 2008. A comparison of concentrations of polycyclic aromatic compounds detected in dust samples from various regions of the world. Environ Int 34(7):988-993. doi:10.1016/j.envint.2008.03.008 PMID:18452990
  • Zhou GD, Donnelly KC, Tian Y, Naspinski C, Gu X, Mertens-Talcott SU. 2008. Pregnane X receptor protects HepG2 cells from BaP-induced DNA damage. Toxicol Sci 104(1):67-73. doi:10.1093/toxsci/kfn058 PMID:18381355

2007

  • Nwaneshiudu OC, Autenrieth RL, McDonald TJ, Donnelly KC, Degollado ED, Abusalih AA. 2007. Risk of polycyclic aromatic hydrocarbon (PAH) exposure from ingested food: The Azerbaijan case study. J Environ Sci Health B 42(2):201-209. PMID:17365335

2006

  • Barr DB, Landsittel D, Nishioka M, Thomas K, Curwin B, Raymer J, Donnelly KC, McCauley L, Ryan PB. 2006. A survey of laboratory and statistical issues related to farmworker exposure studies. Environ Health Perspect 114(6):961-968. PMID:16760001
  • Barr DB, Thomas K, Curwin B, Landsittel D, Raymer J, Lu C, Donnelly KC, Acquavella J. 2006. Biomonitoring of exposure in farmworker studies. Environ Health Perspect 114(6):936-942. PMID:16759998
  • Cho T, Wild JR, Donnelly KC, Tiffany-Castiglioni E. 2006. Degradation of organophosphorus neurotoxicity in SY5Y neuroblastoma cells by organophosphorus hydrolase (OPH). J Toxicol Environ Health A 69(15):1413-1429. PMID:16766477
  • Craft ES, Donnelly KC, Neamtiu I, McCarty KM, Bruce EA, Surkova I, Kim D, Uhnakova I, Gyorffy E, Tesarova E, Anderson BE. 2006. Prioritizing environmental issues around the world: opinions from an international Central and Eastern European environmental health conference. Environ Health Perspect 114(12):1813-7. PMID:17185268
  • Donnelly KC, Cizmas LH. 2006. Environmental Health in Central and Eastern Europe. In: Environmental Health in Central and Eastern Europe. Springer Netherlands, Netherlands. pp.1-247.
  • Matson CW, Lambert MM, McDonald TJ, Autenrieth RL, Donnelly KC, Islamzadeh A, Politov DI, Bickham JW. 2006. Evolutionary toxicology: population-level effects of chronic contaminant exposure on the marsh frogs (Rana ridibunda) of Azerbaijan. Environ Health Perspect 114(4):547-552. PMID:16581544
  • Tiffany-Castiglioni E, Hong SJ, Qian Y, Tang Y, Donnelly KC. 2006. In vitro models for assessing neurotoxicity of mixtures. Neurotoxicology 27(5):835-839. PMID:16843529

2005

  • Donnelly KC, Huebner HJ, Claxton LD, Calvin J, Vos GA, Cizmas LH, He L. 2005. Biodegradation of simple chemical mixtures in soil. Environ Toxicol Chem 24(11):2839-2845. PMID:16398121
  • Matson CW, Palatnikov GM, Islamzadeh A, McDonald TJ, Autenrieth RL, Donnelly KC, Bickham JW. 2005. Chromosomal Damage in two species of aquatic turtles (Emys orbicularis and Mauremys caspica) inhabiting contaminated sites in Azerbaijan. Ecotoxicology 14(5):513-525. PMID:16220359
  • Matson CW, Palatnikov GM, McDonald TJ, Autenrieth RL, Donnelly KC, Anderson TA, Canas JE, Islamzadeh A, Bickham JW. 2005. Patterns of genotoxicity and contaminant exposure: evidence of genomic instability in the marsh frog (Rana Ridibunda) of Sumgayit, Azerbaijan. Environ Toxicol Chem 24:2055-2064. PMID:16152979
  • Wiles MC, Huebner HJ, McDonald TJ, Donnelly KC, Phillips TD. 2005. Matrix-immobilized organoclay for the sorption of polycyclic aromatic hydrocarbons and pentachlorophenol from groundwater. Chemosphere 59(10):1455-1464. PMID:15876388

2004

  • Cizmas LH, Zhou GD, Safe SH, McDonald TJ, Zhu L, Donnelly KC. 2004. Comparative in vitro and in vivo genotoxicities of 7H-benzo[c]fluorene, manufactured gas plant residue (MGP), and MGP fractions. Environ Mol Mutagen 43(3):159-168. doi:10.1002/em.20011 PMID:15065203
  • Donnelly KC, Lingenfelter R, Cizmas LH, Falahatpisheh MH, Qian Y, Tang Y, Garcia SS, Ramos KS, Tiffany-Castiglioni E, Mumtaz MM. 2004. Toxicity assessment of complex mixtures remains a goal. Environ Toxicol Pharmacol 18(2):135-141. doi:10.1016/j.etap.2004.03.013 PMID:21782742
  • Falahatpisheh MH, Kerzee JK, Metz RP, Donnelly KC, Ramos KS. 2004. Inducible cytochrome P450 activities in renal glomerular mesangial cells: biochemical basis for antagonistic interactions among nephrocarcinogenic polycyclic aromatic hydrocarbons. J Carcinog 3(1):12. doi:10.1186/1477-3163-3-12 PMID:15315710 PMCID:PMC516019
  • Reeves WR, McDonald TJ, Cizmas LH, Donnelly KC. 2004. Partitioning and desorption behavior of polycyclic aromatic hydrocarbons from disparate sources. Sci Total Environ 332(1-3):183-192. PMID:15336901
  • Zhou GD, Randerath K, Donnelly KC, Jaiswal AK. 2004. Effects of NQO1 deficiency on levels of cyclopurines and other oxidative DNA lesions in liver and kidney of young mice. Int J Cancer 112(5):877-883. PMID:15386390

2003

  • Ake CL, Wiles MC, Huebner HJ, McDonald TJ, Cosgriff D, Richardson MB, Donnelly KC, Phillips TD. 2003. Porous organoclay composite for the sorption of polycyclic aromatic hydrocarbons and pentachlorophenol from groundwater. Chemosphere 51(9):835-844. doi:10.1016/S0045-6535(03)00040-7 PMID:12697173
  • Bickham JW, Matson CW, Islamzadeh A, Rowe GT, Donnelly KC, Swartz CD, Autenrieth RL, McDonald TJ, Politov DI, Wickliffe JK, Palatnikov GM, Mekhtiev AA, Kasimov R, Rogers WJ. 2003. Editorial: the unknown environmental tragedy in Sumgayit, Azerbaijan. Ecotoxicology 12(6):505-508. PMID:14680331
  • Cizmas LH, Barhoumi R, Burghardt RC, Reeves WR, He L, McDonald TJ, Donnelly KC. 2003. A comparison of two methods for fractionating complex mixtures in preparation for toxicity analysis. J Toxicol Environ Health A 66(14):1351-1370. PMID:12851116
  • Hong MS, Hong SJ, Barhoumi R, Burghardt RC, Donnelly KC, Wild JR, Venkatraj V, Tiffany-Castiglioni E. 2003. Neurotoxicity induced in differentiated SK-N-SH-SY5Y human neuroblastoma cells by organophosphorus compounds. Toxicol Appl Pharmacol 186(2):110-118. PMID:12639502
  • Mueller DC, Bonner JS, McDonald SJ, Autenrieth RL, Donnelly KC, Lee K, Doe K, Anderson J. 2003. The use of toxicity bioassays to monitor the recovery of oiled wetland sediments. Environ Toxicol Chem 22(9):1945-1955. PMID:12959519
  • Swartz CD, Donnelly KC, Islamzadeh A, Rowe GT, Rogers WJ, Palatnikov GM, Mekhtiev AA, Kasimov R, McDonald TJ, Wickliffe JK, Presley BJ, Bickham JW. 2003. Chemical contaminants and their effects in fish and wildlife from the industrial zone of Sumgayit, Republic of Azerbaijan. Ecotoxicology 12(6):509-521. PMID:14680332
  • Tang Y, Donnelly KC, Tiffany-Castiglioni E, Mumtaz MM. 2003. Neurotoxicity of polycyclic aromatic hydrocarbons and simple chemical mixtures. J Toxicol Environ Health A 66(10):919-940. PMID:12825237

2002

  • Barhoumi R, Mouneimne Y, Awooda I, Safe SH, Donnelly KC, Burghardt RC. 2002. Characterization of calcium oscillations in normal and benzo[a]pyrene-treated clone 9 cells. Toxicol Sci 68(2):444-450. PMID:12151640
  • Reese ED, Harris BC, Dimitriou-Christidis P, Autenrieth RL, Donnelly KC, McDonald TJ. 2002. Applicability of Toxic Equivalency Factors (TEFs) For Risk Assessment of Complex Mixtures. In: Proceedings of the Society of Environmental Toxicology and Chemistry 23rd Annual Meeting in North America. Salt Lake City, UT.
  • Ress NB, Donnelly KC, George S. 2002. The effect of pentachlorophenol on DNA adduct formation in p53 wild-type and knockout mice exposed to benzo[a]pyrene. Cancer Lett 178(1):11-17. PMID:11849736

2001

  • Bordelon NR, Donnelly KC, George S. 2001. Pentachlorophenol potentiates benzo[a]pyrene DNA adduct formation in adult but not infant B6C3F1 male mice. Environ Mol Mutagen 37(2):164-172. PMID:11246223
  • Falahatpisheh MH, Donnelly KC, Ramos KS. 2001. Antagonistic interactions among nephrotoxic polycyclic aromatic hydrocarbons. J Toxicol Environ Health A 62(7):543-560. PMID:11289703
  • Reese ED, Harris BC, Dimitriou-Christidis P, Autenrieth RL, Donnelly KC, McDonald TJ. 2001. Risk Assessment of Complex Mixtures: Development of Toxic Equivalency Factors to Improve Toxicity Assessment. In: Proceedings of the Seventh International Congress on Combustion By-Products: Origins, Fate, and Health Effects. Research Triangle Park, NC.
  • Reeves WR, Barhoumi R, Burghardt RC, Lemke SL, Mayura K, McDonald TJ, Phillips TD, Donnelly KC. 2001. Evaluation of methods for predicting the toxicity of polycyclic aromatic hydrocarbon mixtures. Environ Sci Technol 35(8):1630-1636. doi:10.1021/es001689a PMID:11329713
  • Reeves WR, McDonald TJ, Bordelon NR, George S, Donnelly KC. 2001. Impacts of aging on in vivo and in vitro measurements of soil-bound polycyclic aromatic hydrocarbon availability. Environ Sci Technol 35(8):1637-1643. PMID:11329714
  • Washburn KS, Donnelly KC, Huebner HJ, Burghardt RC, Sewall TC, Claxton LD. 2001. A study of 2,4,6-trinitrotoluene inhibition of benzo[a]pyrene uptake and activation in a microbial mutagenicity assay. Chemosphere 44(8):1703-1709. PMID:11534902

2000

  • Bordelon NR, Donnelly KC, King LC, Wolf DC, Reeves WR, George S. 2000. Bioavailability of genotoxic compounds in coal tar contaminated soils in Fisher 344 rats. Toxicol Sci 56(1):37-48. doi:10.1093/toxsci/56.1.37 PMID:10869452
  • Cho T, Wild JR, Donnelly KC. 2000. Utility of organophosphorus hydrolase for the remediation of mutagenicity of methyl parathion. Environ Toxicol Chem 19(8):2022-2028.
  • Garcia S, Donnelly KC. 2000. Genotoxicity analysis of contaminated environmental media. In: Bioremediation and Land Reclamation: Tools to measure Success or Failure. John Wiley and Sons, Ltd, Sussex, United Kingdom.

1999

  • Mayura K, Huebner HJ, Dwyer MR, McKenzie KS, Donnelly KC, Kubena LF, Phillips TD. 1999. Multi-bioassay approach for assessing the potency of complex mixtures of polycyclic aromatic hydrocarbons. Chemosphere 38(8):1721-1732. PMID:10101844
  • Randerath K, Randerath E, Zhou GD, Supungpong N, He L, McDonald TJ, Donnelly KC. 1999. Genotoxicity of complex PAH mixtures recovered from contaminated lake sediments as assessed by three different methods. Environ Mol Mutagen 33:303-312. PMID:10398378
  • Springman KR, Mayura K, McDonald TJ, Donnelly KC, Kubena LF, Phillips TD. 1999. Organoclay adsorption of wood-preserving waste from groundwater. Environ Toxicol Chem 71(1-2):247-259.

1998

  • Donnelly KC, Claxton LD, Huebner HJ, Capizzi JL. 1998. Mutagenic interactions of model chemical mixtures. Chemosphere 37:1253-1261. PMID:9734320

1997

  • Brooks LR, Jacobson RW, Warren SH, Kohan MJ, Donnelly KC, George S. 1997. Mutagenicity of HPLC-fractionated urinary metabolites from 2,4,6-trinitrotoluene-treated Fisher 344 rats. Environ Mol Mutagen 30:298-302. PMID:9366908
  • Clement BG, Donnelly KC, Ake, Jr., Garcia S, Chen I, Willett KL, Safe SH, Shalat SL. 1997. Chemical and bioassay analysis of water and soil extracts from South Texas. Organohalogen Compounds 32:216-219.
  • Collie SL, Donnelly KC. 1997. Measurement of Mutagenic Activity in Contaminated Soils. In: Protocols in Bioremediation. Humana Press, Totowa, NJ. pp.127-151.
  • Donnelly KC, Chen JC, Huebner HJ, Brown K, Autenrieth RL, Bonner JS. 1997. Utility of 4 strains of white rot fungi for the detoxification of 2,4,6-trinitrotoluene in liquid culture. Environ Toxicol Chem 16(6):1105-1110.
  • Donnelly KC, Phillips TD, Onufrock AM, Collie SL, Huebner HJ. 1997. Genotoxicity model and complex mixtures of polycyclic aromatic hydrocarbons. In: Environmental Toxicology and Risk Assessment: Biomarkers and Risk Assessment. ASTM Special Tech. Publ. 1071-720X, Vol. 1306, Am. Soc. for Testing and Materials, Philadelphia, PA. pp.138-148.
  • Donnelly KC, Washburn KS, Huebner HJ. 1997. Remediation and risk assessment of contaminated soils. Biotechnology International 1:221-229.
  • Onufrock AM, Donnelly KC. 1997. Mutagenic potential of fractions and reconstituted mixtures of polycyclic aromatic hydrocarbons. In: Environmental Toxicology and Risk Assessment: Biomarkers and Risk Assessment. ASTM Special Tech. Publ. 1071-720X, Vol. 1306, Am. Soc. for Testing and Materials, Philadelphia, PA.
  • Randerath K, Zhou GD, Randerath E, Safe SH, Donnelly KC. 1997. Comparative [32P]-postlabeling analysis of exogenous and endogenous DNA adducts in mouse skin exposed to a wood-preserving waste extract, a complex mixture of polycyclic and polychlorinated chemicals. Environ Mol Mutagen 29(4):372-378. PMID:9212788

1996

  • Barbee GC, Brown K, Thomas JC, Donnelly KC, Murray HE. 1996. Mutagenic activity (Ames test) of wood-preserving waste sludge applied to soil. Bull Environ Contam Toxicol 57:54-62. PMID:8661460
  • Bordelon NR, Washburn KS, He L, Donnelly KC. 1996. Bioavailability of Genotoxic Mixtures in Soil. In: Proceedings of the Hazardous Substance Research Center (HSRC) / Waste-Management Education & Research Consortium Joint Conference on the Environment. pp.560-568.
  • Donnelly KC, Huebner HJ. 1996. Bioassay-based risk assessment of complex mixtures. In: Superfund Risk Assessment in Soil Contamination Studies. ASTM Special Technical Publication 0066-0558, Vol. 1264. American Society for Testing and Materials, pp.132-148.
  • Donnelly KC, Thomas JC, Brown K. 1996. Mutagenic potential of environmental samples before and after remediation of a solvent contaminated site. Environ Toxicol Chem 14(6):1281-1286.
  • Markiewicz KV, Howie LE, Safe SH, Donnelly KC. 1996. Mutagenic potential of binary and complex mixtures using different enzyme induction systems. J Toxicol Environ Health A 47:443-451. PMID:8614014
  • Randerath E, Zhou GD, Donnelly KC, Safe SH, Randerath K. 1996. DNA damage induced in mouse tissues by organic wood preserving waste extracts as assayed by 32P-postlabeling. Arch Toxicol 70(11):683-695. PMID:8896714
  • Washburn KS, Huebner HJ, Safe SH, Phillips TD, Donnelly KC. 1996. Development of an Instrumental Fractionation and Quantitation Scheme for Selected Polynuclear Aromatic Hydrocarbons Present in extracts from Wood-Preserving Waste. In: Proceedings of the Hazardous Substance Research Center (HSRC) / Waste-Management Education & Research Consortium Joint Conference on the Environment. pp.400-407.

1995

  • Collie SL, Donnelly KC, Bae B, Autenrieth RL, Bonner JS. 1995. Degradation of 2,4,6-trinitrotoluene in an aerobic bioreactor. Chemosphere 32(4):3025-3032.
  • Donnelly KC, Safe SH, Randerath K. 1995. Bioassay-based risk assessment of complex mixtures. J Hazard Mater 41:341-350.
  • Hong MS, Dale BE, Donnelly KC. 1995. Detoxification of pentachlorophenol using KPEG dehalogenation. Environ Sci Technol 29(3):702-708.
  • Hong MS, Dale BE, Donnelly KC. 1995. Genotoxicity profiles for wood preserving waste after KPEG chemical dehalogenation. Environ Sci Technol 29(3):702.
  • Hong MS, He L, Dale BE, Donnelly KC. 1995. Genotoxicity profiles and reaction characteristics of potassium polyethylene glycol dehalogenation of wood preserving waste. Environ Sci Technol 29(3):702-708. doi:10.1021/es00003a018 PMID:22200279
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