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Person Details: April Z. Gu

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Superfund Research Program

April Z. Gu

Cornell University
263 Hollister Hall
Ithaca, New York 14850
Phone: 607-255-8778
Email: aprilgu@cornell.edu

Projects

Research Briefs

Publications

2022

  • Rahman SM, Lan J, Kaeli D, Dy J, Alshawabkeh AN, Gu AZ. 2022. Machine learning-based biomarkers identification from toxicogenomics - bridging to regulatory relevant phenotypic endpoints. J Hazard Mater 423:doi:10.1016/j.jhazmat.2021.127141 PMID:34560480

2021

  • Jiang T, Amadei CA, Lin Y, Gao N, Rahman SM, Lan J, Vecitis CD, Gu AZ. 2021. Dependence of graphene oxide (GO) toxicity on oxidation level, elemental composition, and size. Int J Mol Sci 22(19):doi:10.3390/ijms221910578 PMID:34638921 PMCID:PMC8508828
  • Sevillano M, Vosloo S, Cotto I, Dai Z, Jiang T, Santiago Santana JM, Padilla IY, Rosario-Pabon Z, Velez-Vega C, Cordero JF, Alshawabkeh AN, Gu AZ, Pinto A. 2021. Spatial-temporal targeted and non-targeted surveys to assess microbiological composition of drinking water in Puerto Rico following Hurricane Maria. Water Res 13:doi:10.1016/j.wroa.2021.100123 PMID:34704006 PMCID:PMC8524244

2020

  • Jiang T, Amadei CA, Gou N, Lin Y, Lan J, Vecitis CD, Gu AZ. 2020. Toxicity of single-walled carbon nanotubes (SWCNTs): Effect of lengths, functional groups and electronic structures revealed by a quantitative toxicogenomics assay. Environ Sci Nano 7:1348-1364. doi:10.1039/d0en00230e

2019

  • Muenter MM, Aiken A, Akanji JO, Baig S, Bellou S, Carlson A, Conway C, Cowell CM, DeLateur NA, Hester A, Joshi C, Kramer C, Leifer BS, Nash E, Qi MH, Travers M, Wong KC, Hu M, Gou N, Giese RW, Gu AZ, Beuning PJ. 2019. The response of Escherichia coli to the alkylating agents chloroacetaldehyde and styrene oxide. Mutat Res 840:1-10. doi:10.1016/j.mrgentox.2019.02.001 PMID:30857727 PMCID:PMC6525637

2018

  • Dong S, Feric Z, Li X, Rahman SM, Li G, Wu C, Gu AZ, Dy J, Kaeli D. 2018. A hybrid approach to identify key indicators of PROTECT (Puerto Rico Testsite for Exploring Contamination Threats) dataset with an end-to-end toolchain. In: 2018 IEEE International Conference on Big Data (Big Data). (). IEEE, New York, NY.
  • Dong S, Feric Z, Li X, Rahman SM, Li G, Wu C, Gu AZ, Dy J, Kaeli D, Meeker JD, Padilla IY, Cordero JF, Velez Vega CM, Rosario Z, Alshawabkeh AN. 2018. A hybrid approach to identifying key factors in environmental health studies. In: 2018 IEEE International Conference on Big Data (Big Data). (). IEEE, New York, NY.
  • Dong S, Feric Z, Li X, Rahman SM, Li G, Wu C, Gu AZ, Dy J, Kaeli D, Meeker JD, Padilla IY, Cordero JF, Velez Vega CM, Rosario Z, Alshawabkeh AN. 2018. A hybrid approach to identifying key factors in environmental health studies. Big Data 2855-2862.
  • Lan J, Rahman SM, Gou N, Jiang T, Plewa MJ, Alshawabkeh AN, Gu AZ. 2018. Genotoxicity assessment of drinking water disinfection byproducts by DNA damage and repair pathway profiling analysis. Environ Sci Technol 52(11):6565-6575. doi:10.1021/acs.est.7b06389 PMID:29660283

2017

  • Zhang Y, Gu AZ, He M, Li D, Chen J. 2017. Subinhibitory concentrations of disinfectants promote the horizontal transfer of multidrug resistance genes within and across genera. Environ Sci Technol 51(1):570-580. doi:10.1021/acs.est.6b03132 PMID:27997135

2016

  • Lan J, Gou N, Rahman SM, Gao C, He M, Gu AZ. 2016. A quantitative toxicogenomics assay for high-throughput and mechanistic genotoxicity assessment and screening of environmental pollutants. Environ Sci Technol 50(6):3202-3214. doi:10.1021/acs.est.5b05097 PMID:26855253
  • Li D, Zeng S, Gu AZ, He M. 2016. Water disinfection byproducts induce antibiotic resistance-role of environmental pollutants in resistance phenomena. Environ Sci Technol 50(6):3193-3201. doi:10.1021/acs.est.5b05113 PMID:26928861

2015

  • Gao C, Weisman D, Lan J, Gou N, Gu AZ. 2015. Toxicity mechanisms identification via gene set enrichment analysis of time-series toxicogenomics data: impact of time and concentration. Environ Sci Technol 49(7):4618-4626. doi:10.1021/es505199f PMID:25785649
  • Lan J, Hu M, Gao C, Alshawabkeh AN, Gu AZ. 2015. Toxicity assessment of 4-methyl-1-cyclohexanemethanol and its metabolites in response to a recent chemical spill in West Virginia, USA. Environ Sci Technol 49(10):6284-6293. doi:10.1021/acs.est.5b00371 PMID:25961958

2014

  • Gou N, Yuan S, Lan J, Gao C, Alshawabkeh AN, Gu AZ. 2014. A quantitative toxicogenomics assay reveals the evolution and nature of toxicity during the transformation of environmental pollutants. Environ Sci Technol 48(15):8855-8863. doi:10.1021/es501222t PMID:25010344 PMCID:PMC4123925
  • Lan J, Gou N, Gao C, He M, Gu AZ. 2014. Comparative and mechanistic genotoxicity assessment of nanomaterials via a quantitative toxicogenomics approach across multiple species. Environ Sci Technol 48(21):12937-12945. doi:10.1021/es503065q PMID:25338269 PMCID:PMC4224493

2013

2012

  • O'Connor SF, Lan J, North M, Loguinov AV, Zhang L, Smith MT, Gu AZ, Vulpe CD. 2012. Genome-wide functional and stress response profiling reveals toxic mechanism and genes required for tolerence to benzo[a]pyrene in S. cerevisiae. Front Genet 3:316. doi:10.3389/fgene.2012.00316 PMID:23403841 PMCID:PMC3567348

2004

  • Gu AZ, Hedlund BP, Staley JT, Strand SE, Stensel HD. 2004. Analysis and comparison of the microbial community structures of two enrichment cultures capable of reductively dechlorinating TCE and cis-DCE. Environ Microbiol 6(1):45-54. PMID:14686940

2003

  • Gu AZ, Stensel HD, Pietari JM, Strand SE. 2003. Vinyl bromide as a surrogate for determining vinyl chloride reductive dechlorination potential. Environ Sci Technol 37(19):4410-4416. PMID:14572093
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