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Your Environment. Your Health.

Person Details: Stefano Monti

Superfund Research Program

Stefano Monti

Boston University
75 E. Newton St.
Boston, Massachusetts 02118
Phone: 617-414-7031


Research Briefs



  • Kim S, Reed E, Monti S, Schlezinger JJ. 2021. A data-driven transcriptional taxonomy of adipogenic chemicals to identify white and brite adipogens. Environ Health Perspect 129(7):77006. doi:10.1289/EHP6886 PMID:34323617 PMCID:PMC8320370
  • Reed E, Monti S. 2021. Multi-resolution characterization of molecular taxonomies in bulk and single-cell transcriptomics data. Nucleic Acids Res 49(17):doi:10.1093/nar/gkab552 PMID:34226941 (ahead of print)


  • Chen L, Ouyang J, Wienand K, Bojarczuk K, Hao Y, Chapuy B, Neuberg D, Juszczynski P, Lawton LN, Rodig S, Monti S, Shipp M. 2019. CXCR4 upregulation is an indicator of sensitivity to B-cell receptor/PI3K blockade and a potential resistance mechanism in B-cell receptor-dependent diffuse large B-cell lymphomas. Haematologica doi:10.3324/haematol.2019.216218 PMID:31471373 (in press)
  • Federico A, Karagiannis T, Karri K, Kishore D, Koga Y, Campbell J, Monti S. 2019. Pipeliner: a nextflow-based framework for the definition of sequencing data processing pipelines. Front Genet 10:614. doi:10.3389/fgene.2019.00614 PMID:31316552 PMCID:PMC6609566
  • Federico A, Monti S. 2019. hypeR: An R Package for Geneset Enrichment Workflows. Bioinformatics PMID:31498385 (in press)
  • Kartha V, Sebastiani P, Kern J, Zang L, Varelas X, Monti S. 2019. CaDrA: A computational framework for performing candidate driver analyses using genomic features. Front Genet 10:121. doi:10.3389/fgene.2019.00121 PMID:30838036 PMCID:PMC6390206
  • Li A, Chapuy B, Varelas X, Sebastiani P, Monti S. 2019. Identification of candidate cancer drivers by integrative epi-DNA and gene expression (iEDGE) data analysis. Sci Rep 9:16904. doi:10.1038/s41598-019-52886-z PMID:31729402 PMCID:PMC6858347
  • Li A, Lu X, Natoli T, Bittker J, Sipes N, Subramanian A, Auerbach SS, Sherr DH, Monti S. 2019. The Carcinogenome Project: in vitro gene expression profiling of chemical perturbations to predict long-term carcinogenicity. Environ Health Perspect 127:47002. doi:10.1289/EHP3986 PMID:30964323 PMCID:PMC6785232
  • Reed E, Moses E, Xiao X, Liu G, Campbell J, Perdomo C, Monti S. 2019. Assessment of a highly multiplexed RNA sequencing platform and comparison to existing high-throughput gene expression profiling techniques. Front Genet 10:150. doi:10.3389/fgene.2019.00150 PMID:30891063 PMCID:PMC6411637
  • Sebastiani P, Monti S, Morris M, Gurinovich A, Toshiko T, Andersen SL, Sweigart B, Ferrucci L, Jennings LL, Glass DJ, Perls TT. 2019. A Serum Protein Signature of APOE Genotypes in Centenarian. Aging-US doi:10.1111/acel.13023 PMID:31385390 PMCID:PMC6826130 (in press)


  • Kim S, Li A, Monti S, Schlezinger JJ. 2018. Tributyltin induces a transcriptional response without a brite adipocyte signature in adipocyte models. Arch Toxicol 1-16. doi:10.1007/s00204-018-2268-y PMID:30027469
  • Narasimhan S, Zulick ES, Novikov O, Parks A, Schlezinger JJ, Wang Z, Laroche F, Feng H, Mulas F, Monti S, Sherr DH. 2018. Towards resolving the pro- and anti-tumor effects of the aryl hydrocarbon receptor. Int J Mol Sci 19:24. doi:10.3390/ijms19051388 PMID:29735912 PMCID:PMC5983651



  • Chapuy B, Cheng H, Watahiki A, Ducar M, Tan Y, Chen L, Roemer M, Ouyang J, Christie A, Zhang L, Gusenleitner D, Abo R, Farinha P, von Bonin F, Thorner A, Sun H, Gascoyne R, Pinkus G, van Hummelen P, Wulf G, Aster J, Weinstock D, Monti S, Rodig S, Wang Y, Shipp M. 2016. Diffuse large B-cell lymphoma patient-derived xenograft models capture the molecular and biological heterogeneity of the disease. Blood 127(18):2203-2213. doi:10.1182/blood-2015-09-672352 PMID:26773040 PMCID:PMC4859195
  • Stanford EA, Ramirez-Cardenas A, Wang Z, Novikov O, Alamoud K, Koutrakis P, Mizgerd JP, Genco CA, Kukuruzinska M, Monti S, Bais MV, Sherr DH. 2016. Role for the aryl hydrocarbon receptor and diverse ligands in oral squamous cell carcinoma migration and tumorigenesis. Mol Cancer Res 14(8):696-706. doi:10.1158/1541-7786.MCR-16-0069 PMID:27130942 PMCID:PMC4987205
  • Stanford EA, Wang Z, Mulas F, Landesman-Bollag E, Monti S, Smith BW, Seldin DC, Murphy GJ, Sherr DH. 2016. The role of the aryl hydrocarbon receptor in the development of cells with the molecular and functional characteristics of cancer stem-like cells. BMC Biol 14:20. doi:10.1186/s12915-016-0240-y PMID:26984638 PMCID:PMC4794823
  • Stanford EA, Wang Z, Novikov O, Ramirez-Cardenas A, Mulas F, Landesman-Bollag E, Monti S, Smith BW, Bais MV, Kukuruzinska M, Murphy GJ, Sherr DH. 2016. A role for the aryl hydrocarbon receptor (Ahr) in the production and function of breast and oral cancer stem-like cells and the potential therapeutic value of Ahr modulators. Toxicol Lett 259:S20. doi:10.1016/j.toxlet.2016.07.090
  • Stawski L, Kartha V, Han R, Haines P, Gallagher G, Noonan V, Kukuruzinska M, Monti S, Trojanowska M. 2016. PDGFRβ is a novel marker of stromal activation in oral squamous cell carcinomas. PLoS One 11(4):e0154645. doi:10.1371/journal.pone.0154645 PMID:27128408 PMCID:PMC4851360
  • Voena C, Varesio L, Zhang L, Menotti M, Poggio T, Panizza E, Wang Q, Minero V, Fagoonee S, Compagno M, Altruda F, Monti S, Chiarle R. 2016. Oncogenic ALK regulates EMT in non-small cell lung carcinoma through repression of the epithelial splicing regulatory protein 1. Oncotarget 7(22):33316-33330. doi:10.18632/oncotarget.8955 PMID:27119231 PMCID:PMC5078097


  • Gusenleitner D, Auerbach SS, Melia T, Gomez HF, Sherr DH, Monti S. 2014. Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action. PLoS One 9(7):e102579. doi:10.1371/journal.pone.0102579 PMID:25058030 PMCID:PMC4109923
  • Kleensang A, Maertens A, Rosenberg M, Fitzpatrick S, Lamb J, Auerbach SS, Brennan R, Crofton K, Gordon B, Fornace AJ, Gaido KW, Gerhold D, Haw R, Henney A, Ma'ayan A, McBride M, Monti S, Ochs MF, Pandey A, Sharan R, Stierum R, Tugendreich S, Willett C, Wittwehr C, Xia J, Patton GW, Arvidson K, Bouhifd M, Hogberg HT, Luechtefeld T, Smirnova L, Zhao L, Adeleye Y, Kanehisa M, Carmichael PL, Andersen ME, Hartung T. 2014. t4 workshop report: Pathways of toxicity. ALTEX 31(1):53-61. doi:10.14573/altex.1309261 PMID:24127042 PMCID:PMC4041485


  • Leung A, Nah SK, Reid W, Ebata A, Koch CM, Monti S, Genereux JC, Wiseman RL, Wolozin B, Connors LH, Berk JL, Seldin DC, Mostoslavsky G, Kotton DN, Murphy GJ. 2013. Induced pluripotent stem cell modeling of multisystemic, hereditary transthyretin amyloidosis. Stem Cell Reports 1(5):451–463. doi:10.1016/j.stemcr.2013.10.003 PMID:24286032 PMCID:PMC3841264
  • Sherr DH, Monti S. 2013. The role of the aryl hydrocarbon receptor in normal and malignant B cell development. Semin Immunopathol 35(6):705-716. doi:10.1007/s00281-013-0390-8 PMID:23942720 PMCID:PMC3824572
  • Smith BW, Rozelle SS, Leung A, Ubellacker J, Parks A, Nah SK, French D, Gadue P, Monti S, Chui DK, Steinberg MH, Frelinger AL, Michelson AD, Theberge R, McComb ME, Costello CE, Kotton DN, Mostoslavsky G, Sherr DH, Murphy GJ. 2013. The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation. Blood 122:376-385. doi:10.1182/blood-2012-11-466722 PMID:23723449 PMCID:PMC3716202
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