Superfund Research Program
Trace Elements Analysis Core
The Dartmouth Trace Element Analysis Core (TEAC) provides inorganic analytical support to the Dartmouth Superfund Research Program Center projects. The utility of elemental analysis of human biospecimen as biomarkers of exposure and exposure pathways has continued to expand in work by Everson et al. (2019), Kennedy et al. (2019), Punshon et al. (2019), and Romano et al. (2019), using data from the New Hampshire Birth Cohort (Epidemiology, Biomarkers and Exposure Assessment of Metals Project). In these studies, measurement of placental elemental composition has been linked to placental gene expression, placental gene methylation patterns, placental efficiency and gestational diabetes. The TEAC is a recognized national resource for low-level elemental analysis of a wide range of environmental and human samples. The breadth of the TEAC’s analytical capabilities is reflected in the diversity of its publications in 2019: from studies of arsenic cycling in lakes (Barnett et al., 2019), association between placental cadmium and gene expression (Everson et al., 2019), mercury in cetaceans (McCormack et al., 2019) to tungsten in bone (VanderSchee et al., 2019). Efforts to broaden analytical capabilities to include elemental mapping is also evident in the last year of publications, with publications from Cory-Slechta et al. (2019) and VanderSchee et al. (2019) using the of laser ablation ICP-MS instrumentation and expertise of the TEAC. The TEAC has analyzed 7,210 samples (04/01/19-01/15/20), across the range of services, and 3,958 of these samples were directly associated with Dartmouth Superfund Center researchers. The TEAC has collaborated with other Superfund programs, providing analytical services for Baylor College of Medicine SRP Center and Harvard School of Public Health SRP Center, and Boston University SRP Center.