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Project Publications: University of Washington: Human Dosimetry for Assessment of Exposure to Volatile Compounds

Superfund Research Program

Human Dosimetry for Assessment of Exposure to Volatile Compounds

Project Leader: Michael S. Morgan
Grant Number: P42ES004696
Funding Period: 1995 - 2006

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  • Johns DO, Daniell WE, Shen D, Kalman DA, Dills RL, Morgan MS. 2006. Ethanol-induced increase in the metabolic clearance of 1,1,1-trichloroethane in human volunteers. Toxicol Sci 92(1):61-70. PMID:16638923


  • Johns DO, Dills RL, Morgan MS. 2005. Evaluation of dynamic headspace with gas chromatography/mass spectrometry for the determination of 1,1,1-trichloroethane, trichloroethanol, and trichloroacetic acid in biological samples. J Chromatogr B Analyt Technol Biomed Life Sci 817(2):255-261. PMID:15686993


  • Pierce CH, Chen Y, Hurtle WR, Morgan MS. 2004. Exponential modeling, washout curve reconstruction, and estimation of half-life of toluene and its metabolites. J Toxicol Environ Health A 67(14):1131-1158. PMID:15205028


  • Martin MM, Morgan MS. 2003. Comparison of Re-breathed Breath Sampling to Mixed and End-Exhaled Breath Sampling for Biological Monitoring of Volatile Organic Chemicals. In: Proceedings of the American Industrial Hygiene Conference and Exhibition, May 13. Dallas, TX.


  • Pierce RH, Chen Y, Dills RL, Morgan MS, Kalman DA. 2002. Toluene metabolites as biological indicators of exposure. Toxicol Lett 129(1-2):65-76. PMID:11879975


  • Morgan MS. 2000. Systemic toxicokinetics of inhaled solvents in humans. Biomedical Engineering 28(1):S-46.
  • Wilder L, Morgan MS, Kalman DA, Dills RL. 2000. Analysis of factors influencing urinary metabolite concentrations, including adjustment for urinary flow rate and creatinine or dissolved solids. In: Proceedings of the annual American Industrial Hygiene Conference and Exposition. Orlando, FL.


  • Luderer U, Morgan MS, Brodkin CA, Kalman DA, Faustman EM. 1999. Reproductive endocrine effects of acute toluene exposure in men and women. Occup Environ Med 56(10):657-666. PMID:10658543
  • Pierce CH. 1999. A comparison of 1H8- and 2H8-toluene toxicokinetics in humans. Xenobiotica 29(1):93-108.
  • Vicini P, Pierce CH, Dills RL, Morgan MS, Kalman DA. 1999. Individual prior information in a physiological model of 2H8-toluene kinetics: an empirical Bayes estimation strategy. Risk Anal 19(6):1127-1134. PMID:10765452


  • Betka M. 1998. Stage-specific uptake and retention of cadmium during spermatogenesis. In: Proceedings of the Superfund Basic Research Program (SBRP) Conference, 1998. Boston, MA.
  • Morgan MS. 1998. International comparison of reference values for biological monitoring. Occupational Hygiene 4(4-6):195-213.
  • Pierce CH, Dills RL, Morgan MS, Vicini P, Kalman DA. 1998. Biological monitoring of controlled toluene exposure. Int Arch Occup Environ Health 71:433-444. PMID:9826075


  • Dills RL, Bellamy GM, Kalman DA. 1997. Quantitation of o-, m-, and p-cresol and deuterated analogs in human urine by gas chromatography with electron capture detection. Journal of Chromatographic Science 703:105-113. doi:10.1016/S0378-4347(97)00407-6 PMID:9448067
  • Morgan MS. 1997. The biological exposure indices: a key component in protecting workers from toxic chemicals. Environ Health Perspect 105(supp.1):105-115. PMID:9114280
  • Pierce CH, Dills RL, Lewandowski TA, Morgan MS, Wessels MA, Shen D, Kalman DA. 1997. Estimation of background exposure to toluene using a physiologically-based kinetic model. J Occup Health 39(2):130-137.


  • Pierce CH, Dills RL, Morgan MS, Nothstein GL, Shen D, Kalman DA. 1996. Interindividual differences in 2H8-toluene toxicokinetics assessed by a semi-empirical physiologically-based model. Toxicol Appl Pharmacol 139(1):49-61.
  • Pierce CH, Dills RL, Silvey GW, Kalman DA. 1996. Partition coefficients between human blood or adipose tissue and air for aromatic solvents. Scand J Work Environ Health 22(2):112-118. PMID:8738889
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