Superfund Research Program

Nanoscale Materials in the Environment and their Health Effects

Project Leader: Ian M. Kennedy
Grant Number: P42ES004699
Funding Period: 2010-2015

Project-Specific Links

Publications

2017

• Bonifacio CS, Das GK, Kennedy IM, van Benthem K. 2017. Reduction reactions and densification during in situ TEM heating of iron oxide nanochains. Journal of Applied Physics 122(23):234303. doi:10.1063/1.5004092 PMID:29307918 PMCID:PMC5739907

2016

• Charrier JG, McFall AS, Vu KK, Baroi J, Olea C, Hasson A, Anastasio C. 2016. A bias in the "mass-normalized" DTT response - an effect of non-linear concentration-response curves for copper and manganese. Atmos Environ (1994) 144:325-334. doi:10.1016/j.atmosenv.2016.08.071 PMID:27667959 PMCID:PMC5031483
• Das GK, Anderson DS, Wallis C, Carratt SA, Kennedy IM, Van Winkle LS. 2016. Novel multi-functional europium-doped gadolinium oxide nanoparticle aerosols facilitate the study of deposition in the developing rat lung. Nanoscale 8(22):11518-11530. doi:10.1039/c6nr00897f PMID:27198643 PMCID:PMC5025943
• Patchin ES, Anderson DS, Silva RM, Uyeminami DL, Scott GM, Guo T, Van Winkle LS, Pinkerton KE. 2016. Size-dependent deposition, translocation, and microglial activation of inhaled silver nanoparticles in the rodent nose and brain. Environ Health Perspect 124(12):1870-1875. doi:10.1289/EHP234 PMID:27152509 PMCID:PMC5132640
• Vogel CF, Charrier JG, Wu D, McFall AS, Li W, Abid AD, Kennedy IM, Anastasio C. 2016. Physicochemical properties of iron oxide nanoparticles that contribute to cellular ROS-dependent signaling and acellular production of hydroxyl radical. Free Radic Res 50(11):1153-1164. doi:10.3109/10715762.2016.1152360 PMID:27558512

2015

• Anderson DS, Patchin ES, Silva RM, Uyeminami DL, Sharmah A, Guo T, Das GK, Brown JM, Shannahan JH, Gordon T, Chen L, Pinkerton KE, Van Winkle LS. 2015. Influence of particle size on persistence and clearance of aerosolized silver nanoparticles in the rat lung. Toxicol Sci 144(2):366-381. doi:10.1093/toxsci/kfv005 PMID:25577195 PMCID:PMC4372666
• Anderson DS, Silva RM, Lee D, Edwards PC, Sharmah A, Guo T, Pinkerton KE, Van Winkle LS. 2015. Persistence of silver nanoparticles in the rat lung: influence of dose, size, and chemical composition. Nanotoxicology 9(5):591-602. doi:10.3109/17435390.2014.958116 PMID:25231189 PMCID:PMC4364933
• Davidson R, Anderson DS, Van Winkle LS, Pinkerton KE, Guo T. 2015. Evolution of silver nanoparticles in the rat lung investigated by X-ray absorption spectroscopy. J Phys Chem A 119(2):281-289. doi:10.1021/jp510103m PMID:25517690 PMCID:PMC4298353
• Pinkerton KE, Harbaugh M, Han MK, Le Saux CJ, Van Winkle LS, Martin WF, Martin WJ, Kosgei RJ, Carter E, Sitkin N, Smiley-Jewell SM, George M. 2015. Women and lung disease sex differences and global health disparities. Am J Respir Crit Care Med 192(1):11-16. doi:10.1164/rccm.201409-1740PP PMID:25945507 PMCID:PMC4511423
• Van Winkle LS, Bein KJ, Anderson DS, Pinkerton KE, Tablin F, Wilson D, Wexler AS. 2015. Biological dose response to PM25: effect of particle extraction method on platelet and lung responses. Toxicol Sci 143(2):349-359. doi:10.1093/toxsci/kfu230 PMID:25389146 PMCID:PMC4306718

2014

• Charrier JG, McFall AS, Richards-Henderson NK, Anastasio C. 2014. Hydrogen peroxide formation in a surrogate lung fluid by transition metals and quinones present in particulate matter. Environ Sci Technol 48(12):7010-7017. doi:10.1021/es501011w PMID:24857372 PMCID:PMC4063450
• Das GK, Bonifacio CS, De Rojas J, Liu K, van Benthem K, Kennedy IM. 2014. Ultra-long magnetic nanochains for highly efficient arsenic removal from water. J Mater Chem A Mater 2:12974-12981. doi:10.1039/c4ta02614d PMID:25254112 PMCID:PMC4170064
• Das GK, Stark D, Kennedy IM. 2014. Potential toxicity of up-converting nanoparticles encapsulated with a bilayer formed by ligand attraction. Langmuir 30(27):8167-8176. doi:10.1021/la501595f PMID:24971524 PMCID:PMC4100795
• Villarreal F, Das GK, Abid AD, Kennedy IM, Kültz D. 2014. Sublethal effects of CuO nanoparticles on Mozambique tilapia (Oreochromis mossambicus) are modulated by environmental salinity. PLoS One 9(2):e88723. doi:10.1371/journal.pone.0088723 PMID:24520417 PMCID:PMC3919801

2013

• Abid AD, Anderson DS, Das GK, Van Winkle LS, Kennedy IM. 2013. Novel lanthanide-labeled metal oxide nanoparticles improve the measurement of in vivo clearance and translocation. Part Fibre Toxicol 10:1. doi:10.1186/1743-8977-10-1 PMID:23305071 PMCID:PMC3560106
• Chan JK, Charrier JG, Kodani SD, Vogel CF, Kado SY, Anderson DS, Anastasio C, Van Winkle LS. 2013. Combustion-derived flame generated ultrafine soot generates reactive oxygen species and activates Nrf2 antioxidants differently in neonatal and adult rat lungs. Part Fibre Toxicol 10:34. doi:10.1186/1743-8977-10-34 PMID:23902943 PMCID:PMC3735485
• Chan JK, Kodani SD, Charrier JG, Morin D, Edwards PC, Anderson DS, Anastasio C, Van Winkle LS. 2013. Age-specific effects on rat lung glutathione and antioxidant enzymes after inhaling ultrafine soot. Am J Respir Cell Mol Biol 48:114-124. doi:10.1165/rcmb.2012-0108OC PMID:23065132 PMCID:PMC3547088
• Chan JK, Vogel CF, Baek J, Kodani SD, Uppal RS, Bein KJ, Anderson DS, Van Winkle LS. 2013. Combustion derived ultrafine particles induce cytochrome P-450 expression in specific lung compartments in the developing neonatal and adult rat. Am J Physiol 304(10):L665-L677. doi:10.1152/ajplung.00370.2012 PMID:23502512 PMCID:PMC3652057
• Han J, Kim H, Sudheendra L, Gee SJ, Hammock BD, Kennedy IM. 2013. Photonic crystal lab-on-a-chip for detecting staphylococcal entertoxin B at low attomolar concentration. Anal Chem 85(6):3104-3109. doi:10.1021/ac303016h PMID:23418954 PMCID:PMC3608201
• Kim D, Young TM, Anastasio C. 2013. Phototransformation rate constants of PAHs associated with soot particles. Sci Total Environ 443:896-903. doi:10.1016/j.scitotenv.2012.11.055 PMID:23247292 PMCID:PMC3566770
• McKenzie ER, Young TM. 2013. Quality control considerations for size exclusion chromatography with online ICP-MS: a powerful tool for evaluating the size dependence of metal-organic matter complexation. Water Sci Technol 67(5):1075-1082. doi:10.2166/wst.2013.659 PMID:23416600 PMCID:PMC3577094

2012

• Shen H, Anastasio C. 2012. A comparison of hydroxyl radical and hydrogen peroxide generation in ambient particle extracts and laboratory metal solutions,. Atmos Environ (1994) 46:665-668. doi:10.1016/j.atmosenv.2011.10.006 PMID:22267949 PMCID:PMC3259706
• Wells MA, Abid AD, Kennedy IM, Barakat AI. 2012. Serum proteins prevent aggregation of Fe2O3 and ZnO nanoparticles. Nanotoxicology 6(8):837-846. doi:10.3109/17435390.2011.625131 PMID:22149273 PMCID:PMC3963816

2011

• Chan JK, Fanucchi MV, Anderson DS, Abid AD, Wallis C, Dickinson DA, Kumfer BM, Kennedy IM, Wexler AS, Van Winkle LS. 2011. Susceptibility to inhaled flame-generated ultrafine soot in neonatal and adult rat lungs. Toxicol Sci 124(2):472-486. doi:10.1093/toxsci/kfr233 PMID:21914721 PMCID:PMC3216412
• Charrier JG, Anastasio C. 2011. Impacts of antioxidants on hydroxyl radical production from individual and mixed transition metals in a surrogate lung fluid. Atmos Environ (1994) 45:7555-7562. doi:10.1016/j.atmosenv.2010.12.021 PMID:22125412 PMCID:PMC3223868
• Shen H, Anastasio C. 2011. Formation of hydroxyl radical from San Joaquin Valley particles extracted in a cell-free surrogate lung fluid. Atmos Chem Phys 11(18):9671-9682. doi:10.5194/acp-11-9671-2011 PMID:22121357 PMCID:PMC3223122
• Shi J, Abid AD, Kennedy IM, Hristova KR, Silk WK. 2011. To duckweeds (Landoltia punctata), nanoparticulate copper oxide is more inhibitory than the soluble copper in the bulk solution. Environ Pollut 159(5):1277-1282. doi:10.1016/j.envpol.2011.01.028 PMID:21333422 PMCID:PMC3277788

2010

• Kumfer BM, Shinoda K, Jeyadevan B, Kennedy IM. 2010. Gas-phase flame synthesis and properties of magnetic iron oxide nanoparticles with reduced oxidation state. J Aerosol Sci 41(3):257-265. doi:10.1016/j.jaerosci.2010.01.003 PMID:20228941 PMCID:PMC2835527
• Lee D, Wallis C, Wexler AS, Schelegle ES, Van Winkle LS, Plopper CG, Fanucchi MV, Kumfer BM, Kennedy IM, Chan JK. 2010. Small particles disrupt postnatal airway development. J Appl Physiol 109(4):1115-1124. doi:10.1152/japplphysiol.00295.2010 PMID:20634362 PMCID:PMC4182294
• Van Winkle LS, Chan JK, Anderson DS, Kumfer BM, Kennedy IM, Wexler AS, Wallis C, Abid AD, Sutherland KM, Fanucchi MV. 2010. Age specific responses to acute inhalation of diffusion flame soot particles: cellular injury and the airway antioxidant response. Inhal Toxicol 22(S2):70-83. doi:10.3109/08958378.2010.513403 PMID:20961279 PMCID:PMC3111018

2009

• Gojova A, Lee J, Jung HS, Guo B, Barakat AI, Kennedy IM. 2009. Effect of cerium oxide nanoparticles on inflammation in vascular endothelial cells. Inhal Toxicol 21(s1):123-130. doi:10.1080/08958370902942582 PMID:19558244 PMCID:PMC2859298
• Kim D, Kumfer BM, Anastasio C, Kennedy IM, Young TM. 2009. Environmental aging of polycyclic aromatic hydrocarbons on soot and its effect on source identification. Chemosphere 76(8):1075-1081. doi:10.1016/j.chemosphere.2009.04.031 PMID:19443013 PMCID:PMC2754578
• Rice RH, Vidrio E, Kumfer BM, Qin Q, Willits NH, Kennedy IM, Anastasio C. 2009. Generation of oxidant response to copper and iron nanoparticles and salts: Stimulation by ascorbate. Chem Biol Interact 181(3):359-365. doi:10.1016/j.cbi.2009.08.007 PMID:19683516 PMCID:PMC2763550