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Your Environment. Your Health.

Project Publications: University of California-Berkeley: Using Adductomic Signatures to Evaluate Risks of Superfund Chemicals

Superfund Research Program

Using Adductomic Signatures to Evaluate Risks of Superfund Chemicals

Project Leader: Stephen M. Rappaport
Co-Investigator: Luoping Zhang
Grant Number: P42ES004705
Funding Period: 2017-2022
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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  • Sille FC, Karakitsios S, Kleensang A, Koehler K, Maertens A, Miller G, Prasse C, Quiros-Alcala L, Ramachandran G, Rappaport SM, Rule A, Sarigiannis D, Smirova L, Hartung T. 2020. The exposome: A new approach for risk assessment. ALTEX 37:doi:10.14573/altex.2001051
  • Wheelock CE, Rappaport SM. 2020. The role of gene environment interactions in lung disease: The urgent need for the exposome. European Respiratory Journal 55:doi:10.1183/13993003.02064-2019
  • Yano Y, Schiffman C, Grigoryan H, Hayes J, Edmands WM, Petrick L, Whitehead TP, Metayer C, Dudoit S, Rappaport SM. 2020. Untargeted adductomics of newborn dried blood spots identifies modifications to human serum albumin associated with childhood leukemia. Leuk Res 88:106268. doi:10.1016/j.leukres.2019.106268 PMID:31760269 PMCID:PMC6937378


  • Carlsson H, Rappaport SM, Tornqvist M. 2019. Protein Adductomics: Methodologies for Untargeted Screening of Adducts to Serum Albumin and Hemoglobin in Human Blood Samples. High Throughput 8(1):6. doi:10.3390/ht8010006 PMID:30857166 PMCID:PMC6473736
  • Grigoryan H, Schiffman C, Gunter MJ, Naccarati A, Polidoro S, Dagnino S, Dudoit S, Vineis P, Rappaport SM. 2019. Cys34 adductomics links colorectal cancer with the gut microbiota and redox biology. Cancer Res 79(23):6024-6031. doi:10.1158/0008-5472.CAN-19-1529 PMID:31641032 PMCID:PMC6891211
  • Lee KM, Zhang L, Vermeulen R, Hu W, Bassig BA, Wong JJ, Qiu C, Purdue MP, Wen C, Walker DI, Jones DP, Li L, Huang Y, Rothman N, Smith MT, Lan Q. 2019. Alterations in immune and renal biomarkers among workers occupationally exposed to low levels of trichloroethylene below current regulatory standards. Occup Environ Med 76(6):376-381. doi:10.1136/oemed-2018-105583 PMID:30971425 PMCID:PMC6953904
  • Schiffman C, Petrick L, Perttula K, Yano Y, Carlsson H, Whitehead TP, Metayer C, Hayes J, Rappaport SM, Dudoit S. 2019. Filtering procedures for untargeted LC-MS metabolomics data. BMC Bioinformatics 20(1):334. doi:10.1186/s12859-019-2871-9 PMID:31200644 PMCID:PMC6570933



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