Superfund Research Program
Dioxin-like Compounds Suppress IgM Responses by Targeting CD5+ (Innate-like) B Cells, Which Can Serve as a Biomarker of Susceptibility to Environmental AHR Ligands
Project Leader: Norbert E. Kaminski
Grant Number: P42ES004911
Funding Period: 2022-2027
Project-Specific Links
- Project Summary
Publications
2023
- Khan DI, Karmaus P, Bach A, Crawford RB, Kaminski NE. 2023. An in vitro model of human hematopoiesis identifies a regulatory role for the aryl hydrocarbon receptor. Blood Adv doi:10.1182/bloodadvances.2023010169 PMID:37477592
2022
- Zhou J, Blevins L, Crawford RB, Kaminski NE. 2022. Role of programmed cell death protein-1 and lymphocyte specific protein tyrosine kinase in the aryl hydrocarbon receptor- mediated impairment of the IgM response in human CD5(+) innate-like B cells. Front Immunol doi:10.3389/fimmu.2022.884203 PMID:35558082 PMCID:PMC9088000
2021
- Blevins L, Zhou J, Crawford RB, Kaminski NE. 2021. Identification of a sensitive human immunological target of aryl hydrocarbon receptor activation: CD5+ innate-like B cells. Front Immunol 12:635748. doi:10.3389/fimmu.2021.635748 PMID:33936048 PMCID:PMC8082145