Project Publications: Michigan State University: Computational Modeling Core

Superfund Research Program

Project Leader: Qiang Zhang (The Hamner Institutes for Health Sciences)
Grant Number: P42ES004911
Funding Period: 2022-2027

Mu D, Scharer C, Kaminski NE, Zhang Q. 2024. A multiscale spatial modeling framework for the germinal center response. Front Immunol 15:doi:10.3389/fimmu.2024.1377303 PMID:38881901 PMCID:11179717

Bagga AD, Johnson BP, Zhang Q. 2023. A minimal human physiologically based kinetic model of thyroid hormones and chemical disruption of plasma thyroid hormone binding proteins. Front. Endocrinol 14:1168663. doi:10.3389/fendo.2023.1168663 PMID:37305053 PMCID:PMC1024845
Filipovic D, Qi W, Kana O, Marri D, LeCluyse EL, Andersen ME, Cuddapah S, Bhattacharya S. 2023. Interpretable predictive models of genome-wide aryl hydrocarbon receptor-DNA binding reveal tissue-specific binding determinants. Toxicol Sci 196(2):170-186. doi:10.1093/toxsci/kfad094 PMID:37707797 PMCID:PMC10682972
Kana O, Nault R, Filipovic D, Marri D, Zacharewski T, Bhattacharya S. 2023. Generative modeling of single-cell gene expression for dose-dependent chemical perturbations. Patterns 4(8):100817. doi:10.1016/j.patter.2023.100817 PMID:37602218 PMCID:10436058
Kumbale CM, Zhang Q, Voit EO. 2023. Hepatic cholesterol biosynthesis and dioxin-induced dysregulation: A multiscale computational approach. Food Chem Toxicol 181:114086. doi:10.1016/j.fct.2023.114086 PMID:37820785

Jing L, Zhang Q. 2022. Intrathyroidal feedforward and feedback network regulating thyroid hormone synthesis and secretion. Front. Endocrinol 13:992883. doi:10.3389/fendo.2022.992883 PMID:36187113 PMCID:PMC9519864
Liu R, Zacharewski TR, Conolly RB, Zhang Q. 2022. A physiologically based pharmacokinetic (PBPK) modeling framework for mixtures of dioxin-like compounds. Toxics 10(11):700. doi:10.3390/toxics10110700 PMID:36422908 PMCID:PMC9698634
Liu S, Pi J, Zhang Q. 2022. Signal amplification in the KEAP1-NRF2-ARE antioxidant response pathway. Redox Biol 54:102389. doi:10.1016/j.redox.2022.102389 PMID:35792437 PMCID:PMC9287733
Shi Z, Xia M, Xiao S, Zhang Q. 2022. Identification of nonmonotonic concentration-responses in Tox21 high-throughput screening estrogen receptor assays. Toxicol Appl Pharmacol 452:116206. doi:10.1016/j.taap.2022.116206 PMID:35988584 PMCID:PMC9452481