Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Internet Explorer is no longer a supported browser.

This website may not display properly with Internet Explorer. For the best experience, please use a more recent browser such as the latest versions of Google Chrome, Microsoft Edge, and/or Mozilla Firefox. Thank you.

COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC. Get the latest research information from NIH.

Your Environment. Your Health.

Program Publications: Texas A&M University: Procedures to Assess the Hazards of a Superfund Site

Superfund Research Program

Procedures to Assess the Hazards of a Superfund Site

Center Director: Stephen H. Safe
Grant Number: P42ES004917
Funding Period: 1989-2008

Publications

2019

  • Onel M, Beykal B, Ferguson K, Chiu WA, McDonald TJ, Zhou L, House JS, Wright FA, Sheen D, Rusyn I, Pistikopoulos EN. 2019. Grouping of complex substances using analytical chemistry data: A framework for quantitative evaluation and visualization. PLoS One 14(10):e0223517. doi:10.1371/journal.pone.0223517 PMID:31600275 PMCID:PMC6786635
  • Wang M, Orr AA, He S, Dalaijamts C, Chiu WA, Tamamis P, Phillips TD. 2019. Montmorillonites can tightly bind glyphosate and paraquat reducing toxin exposures and toxicity. ACS Omega 4:17702-17713. doi:10.1021/acsomega.9b02051 PMID:31681876 PMCID:PMC6822125

2018

  • Ahuja S, ed. 2018. Advances in Water Purification Techniques: Meeting the Needs of Developed and Developing Countries Elsevier,
  • Brewster CS, Sharma VK, Cizmas LH, McDonald TJ. 2018. Occurrence, distribution and composition of aliphatic and polycyclic aromatic hydrocarbons in sediment cores from the Lower Fox River, Wisconsin, US. Environ Sci Pollut Res Int 25(5):4974-4988. doi:10.1007/s11356-017-0819-z PMID:29204943 PMCID:PMC5823782
  • Feng M, Jinadatha C, McDonald TJ, Sharma VK. 2018. Accelerated oxidation of organic contaminants by ferrate(VI): The overlooked role of reducing additives. Environ Sci Technol 52(19):11319-11327. doi:10.1021/acs.est.8b03770 PMID:30187746 PMCID:PMC6300057
  • Zheng X, Dupuis KT, Aly NA, Zhou Y, Smith FB, Tang K, Smith RD, Baker ES. 2018. Utilizing ion mobility spectrometry and mass spectrometry for the analysis of polycyclic aromatic hydrocarbons, polychlorinated biphenyls, polybrominated diphenyl ethers and their metabolites. Anal Chim Acta 1037:265-273. doi:10.1016/j.aca.2018.02.054 PMID:30292301 PMCID:PMC6223027
  • Ahuja S, ed. 2018. Remediation of Selenium in Water: A Review. In: Advances in Water Purification Techniques: Meeting the Needs of Developed and Developing Countries. Elsevier,

2015

  • Phillips TD, Richardson MB, Cheng YL, He L, McDonald TJ, Cizmas LH, Safe SH, Donnelly KC, Wang F, Moorthy B, Zhou GD. 2015. Mechanistic relationships between hepatic genotoxicity and carcinogenicity in male B6C3F1 mice treated with polycyclic aromatic hydrocarbon mixtures. Arch Toxicol 89(6):967-977. doi:10.1007/s00204-014-1285-8 PMID:24888377 PMCID:PMC4254891

2014

2013

2012

  • Theodorakis CW, Bickham JW, Donnelly KC, McDonald TJ, Willink PW. 2012. DNA damage in cichlids from an oil production facility in Guatemala. Ecotoxicology 21:496-511. doi:10.1007/s10646-011-0811-1 PMID:22080433

2011

2010

  • Kim J, Erikson D, Burghardt RC, Spencer T, Wu G, Bayless K, Johnson G, Bazer F. 2010. Secreted phosphoprotein 1 binds integrins to initiate multiple cell signaling pathways, including FRAP1/mTOR, to support attachment and force-generated migration of trophectoderm cells. Matrix Biology 29:369-382. doi:10.1016/j.matbio.2010.04.001 PMID:20385232
  • Li X, Mertens-Talcott SU, Zhang S, Kim K, Ball J, Safe SH. 2010. MicroRNA-27a indirectly regulates estrogen receptor {alpha} expression and hormone responsiveness in MCF-7 breast cancer cells. Endocrinology 151(6):2462-2473. doi:10.1210/en.2009-1150 PMID:20382698 PMCID:PMC2875816

2009

2008

  • Barbee GC, Barich J, Duncan B, Bickham JW, Matson CW, Hintze CJ, Autenrieth RL, Zhou GD, McDonald TJ, Cizmas LH, Norton D, Donnelly KC. 2008. In situ biomonitoring of PAH-contaminated sediments using juvenile coho salmon (Oncorhynchus kisutch). Ecotoxicol Environ Saf 71(2):454-464. doi:10.1016/j.ecoenv.2008.01.001 PMID:18304636
  • Finnell RH. 2008. Reproductive consequences of oral arsenate exposure during pregnancy in a mouse model. Birth Defects Research Part B: Developmental and Reproductive Toxicology 83(1):40-7. PMID:18186108
  • Higgins KJ, Liu S, Abdelrahim M, Vanderlaag K, Liu X, Porter WW, Metz RP, Safe SH. 2008. Vascular endothelial growth factor receptor-2 expression is down-regulated by 17beta-estradiol in MCF-7 breast cancer cells by estrogen receptor alpha/Sp proteins. Mol Endocrinol 22(2):388-402. doi:10.1210/me.2007-0319 PMID:18006642 PMCID:PMC2234589
  • Naspinski C, Lingenfelter R, Cizmas LH, Naufal Z, He L, Islamzadeh A, Li Z, Li Z, McDonald TJ, Donnelly KC. 2008. A comparison of concentrations of polycyclic aromatic compounds detected in dust samples from various regions of the world. Environ Int 34(7):988-993. doi:10.1016/j.envint.2008.03.008 PMID:18452990
  • Phillips TD, Afriyie-Gyawu E, Williams J, Huebner HJ, Ankrah N, Ofori-Adjei D, Jolly PE, Johnson N, Taylor JF, Marroquin-Cardona A, Xu L, Tang LS, Wang J. 2008. Reducing human exposure to aflatoxin through the use of clay: a review. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 25(2):134-145. doi:10.1080/02652030701567467 PMID:18286403
  • Safe SH, Kim K. 2008. Non-classical genomic estrogen receptor (ER)/specificity protein and ER/activating protein-1 signaling pathways. J Mol Endocrinol 41(5):263-275. doi:10.1677/JME-08-0103 PMID:18772268 PMCID:PMC2582054
  • Wu F, Khan S, Wu Q, Barhoumi R, Burghardt RC, Safe SH. 2008. Ligand structure-dependent activation of estrogen receptor alpha/Sp by estrogens and xenoestrogens. Psychiatr Pol 110(1-2):104-115. doi:10.1016/j.jsbmb.2008.02.008 PMID:18400491 PMCID:PMC2519242
  • Wu F, Kim K, Martin J, Safe SH. 2008. In vivo profiling of estrogen receptor/specificity protein-dependent transactivation. Endocrinology 149(11):5696-5705. doi:10.1210/en.2008-0720 PMID:18635651 PMCID:PMC2584598
  • Yang W, Tiffany-Castiglioni E. 2008. Paraquat-induced apoptosis in human neuroblastoma SH-SY5Y cells: involvement of p53 and mitochondria. J Toxicol Environ Health A 71(4):289-99. PMID:18253895
  • Zhang S, Safe SH. 2008. Ligand-dependent interactions of the Ah receptor with coactivators in a mammalian two-hybrid assay. Toxicol Appl Pharmacol 227(2):196-206. PMID:18048071
  • Zhou GD, Donnelly KC, Tian Y, Naspinski C, Gu X, Mertens-Talcott SU. 2008. Pregnane X receptor protects HepG2 cells from BaP-induced DNA damage. Toxicol Sci 104(1):67-73. doi:10.1093/toxsci/kfn058 PMID:18381355

2007

  • Bruce EA, Abusalih AA, McDonald TJ, Autenrieth RL. 2007. Comparing deterministic and probabilistic risk assessments for sites contaminated by polycyclic aromatic hydrocarbons (PAHs). J Environ Sci Health A Tox Hazard Subst Environ Eng 42(6):697-706. PMID:17473995
  • Custer CM, Drummer P, Li A, Warburton DH, Melancon MJ, Hoffman DJ, Matson CW, Bickham JW, Custer TW. 2007. Water level management and contaminant exposure to tree swallows nesting on the Upper Mississippi River. Environ Monit Assess 133(1-3):335-345. doi:10.1007/s10661-006-9588-8 PMID:17286172
  • Dash B, Afriyie-Gyawu E, Huebner HJ, Porter WW, Wang J, Jolly PE, Phillips TD. 2007. Determinants of the variability of aflatoxin-albumin adduct levels in Ghanaians. J Toxicol Environ Health A 70(1):58-66. doi:10.1080/15287390600748880 PMID:17162498
  • Dash B, Metz RP, Huebner HJ, Porter WW, Phillips TD. 2007. Molecular characterization of two superoxide dismutases from Hydra vulgaris. Gene 387(1-2):93-108. PMID:17150313
  • Dimitriou-Christidis P, Autenrieth RL, McDonald TJ, Desai AM. 2007. Measurement of biodegradability parameters for single unsubstituted and methylated polycyclic aromatic hydrocarbons in liquid bacterial suspensions. Biotechnol Bioeng 97(4):922-932. doi:10.1002/bit.21268 PMID:17115446
  • Khan S, Liu S, Stoner M, Safe SH. 2007. Cobaltous chloride and hypoxia inhibit aryl hydrocarbon receptor-mediated responses in breast cancer cells. Toxicol Appl Pharmacol 223(1):28-38. PMID:17599377
  • Khan S, Wu F, Liu S, Safe SH, Wu Q. 2007. Role of specificity protein transcription factors in estrogen-induced gene expression in MCF-7 breast cancer cells. J Mol Endocrinol 39(4):289-304. doi:10.1677/JME-07-0043 PMID:17909268
  • Lu W, Zhu H, Wen S, Laurent C, Shaw GM, Lammer EJ, Finnell RH. 2007. Screening for novel PAX3 polymorphisms and risks of spina bifida. Birth Defects Res A Clin Mol Teratol 79(1):45-49. PMID:17149730
  • Nwaneshiudu OC, Autenrieth RL, McDonald TJ, Donnelly KC, Degollado ED, Abusalih AA. 2007. Risk of polycyclic aromatic hydrocarbon (PAH) exposure from ingested food: The Azerbaijan case study. J Environ Sci Health B 42(2):201-209. PMID:17365335
  • Qian Y, Venkatraj J, Barhoumi R, Pal R, Datta A, Wild JR, Tiffany-Castiglioni E. 2007. Comparative non-cholinergic neurotoxic effects of paraoxon and diisopropyl fluorophosphate (DFP) on human neuroblastoma and astrocytoma cell lines. Toxicol Appl Pharmacol 219(2-3):162-171. PMID:17223147
  • Safe SH, Khan S, Wu F, Li X. 2007. Chemical-induced estrogenicity. In: Veterinary Toxicology: Basic and Clinical Principles. Elsevier, New York,
  • Shaw GM, Jelliffe-Pawlowski L, Nelson V, Zhu H, Harris JA, Finnell RH. 2007. Infant C677T MTHFR polymorphism and severe mental retardation. Birth Defects Res A Clin Mol Teratol 79(1):24-26. PMID:17149733
  • Sobol E, Yagen B, Lamb JG, White HS, Wlodarczyk BJ, Finnell RH, Bialer M. 2007. Anticonvulsant activity, neural tube defect induction, mutagenicity and pharmacokinetics of a new potent antiepileptic drug, N-methoxy-2,2,3,3-tetramethylcyclopropane carboxamide. Epilepsy Res 73(1):75-84. PMID:16997532
  • White LD, Cory-Slechta DA, Gilbert ME, Tiffany-Castiglioni E, Zawia NH, Virgolini M, Rossi-George A, Lasley SM, Qian Y, Basha M. 2007. New and evolving concepts in the neurotoxicology of lead. Toxicol Appl Pharmacol 225(1):1-27. doi:10.1016/j.taap.2007.08.001 PMID:17904601
  • Wu F, Safe SH. 2007. Differential activation of wild-type estrogen receptor alpha and C-terminal deletion mutants by estrogens, antiestrogens and xenoestrogens in breast cancer cells. Psychiatr Pol 103(1):1-9. PMID:17141713
  • Gupta RC, ed. 2007. Veterinary Toxicology: Basic and Clinical Principles Elsevier, New York,

2006

  • Abdelrahim M, Ariazi E, Kim K, Khan S, Barhoumi R, Burghardt RC, Liu S, Hill DS, Finnell RH, Wlodarczyk BJ, Jordan VC, Safe SH. 2006. 3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha. Cancer Res 66(4):2459-2467. doi:10.1158/0008-5472.CAN-05-3132 PMID:16489053
  • Barhoumi R, Awooda I, Mouneimne Y, Safe SH, Burghardt RC. 2006. Effects of benzo-a-pyrene on oxytocin-induced Ca2+ oscillations in myometrial cells. Toxicol Lett 165(2):133-141. PMID:16567066
  • Barr DB, Landsittel D, Nishioka M, Thomas K, Curwin B, Raymer J, Donnelly KC, McCauley L, Ryan PB. 2006. A survey of laboratory and statistical issues related to farmworker exposure studies. Environ Health Perspect 114(6):961-968. PMID:16760001
  • Barr DB, Thomas K, Curwin B, Landsittel D, Raymer J, Lu C, Donnelly KC, Acquavella J. 2006. Biomonitoring of exposure in farmworker studies. Environ Health Perspect 114(6):936-942. PMID:16759998
  • Blom HJ, Shaw GM, den Heijer M, Finnell RH. 2006. Neural tube defects and folate: case far from closed. Nat Rev Neurosci 7(9):724-731. PMID:16924261
  • Carmichael SL, Shaw GM, Iovannisci DM, Yang W, Finnell RH, Cheng S, Lammer EJ. 2006. Risks of human limb deficiency anomalies associated with 29 SNPs of genes involved in homocysteine metabolism, coagulation, cell-cell interactions, inflammatory response, and blood pressure regulation. American Journal of Medical Genetics Part A 140A(22):2422-2440. PMID:17036337
  • Cho T, Wild JR, Donnelly KC, Tiffany-Castiglioni E. 2006. Degradation of organophosphorus neurotoxicity in SY5Y neuroblastoma cells by organophosphorus hydrolase (OPH). J Toxicol Environ Health A 69(15):1413-1429. PMID:16766477
  • Custer TW, Custer CM, Goatcher BL, Melancon MJ, Matson CW, Bickham JW. 2006. Contaminant exposure of barn swallows nesting on Bayou D'Inde, Calcasieu Estuary, Louisiana, USA. Environ Monit Assess 121(1-3):541-558. PMID:16779575
  • Dash B, Afriyie-Gyawu E, Huebner HJ, Porter WW, Wang J, Jolly PE, Phillips TD. 2006. Noninvasive identification of interindividual variation in xenobiotic-metabolizing enzymes: implications for cancer epidemiology and biomarker studies. J Toxicol Environ Health A 69(13):1203-1216. PMID:16754536
  • Donnelly KC, Cizmas LH. 2006. Environmental Health in Central and Eastern Europe. In: Environmental Health in Central and Eastern Europe. Springer Netherlands, Netherlands. pp.1-247.
  • Enaw JO, Zhu H, Yang W, Lu W, Shaw GM, Lammer EJ, Finnell RH. 2006. CHKA and PCYT1A gene polymorphisms, choline intake and spina bifida risk in a California population. BMC Med 4:36. PMID:17184542
  • Jolly PE, Jiang Y, Ellis W, Awuah R, Nnedu O, Phillips TD, Wang J, Afriyie-Gyawu E, Tang L, Person S, Williams J, Jolly CM. 2006. Determinants of aflatoxin levels in Ghanaians: Sociodemographic factors, knowledge of aflatoxin and food handling and consumption practices. Int J Hyg Environ Health 209(4):345-358. PMID:16644281
  • Khan S, Konstantinov A, Chittim B, McAlees A, Yeo B, Safe SH. 2006. Structure-dependent Ah receptor agonist activities of chlorinated biphenylenes. Toxicol In Vitro 20(7):1234-1237. PMID:16759834
  • Liu S, Abdelrahim M, Khan S, Ariazi E, Jordan VC, Safe SH. 2006. Aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha in MCF-7 breast cancer cells. Biol Chem 387(9):1209-1213. doi:10.1515/BC.2006.149 PMID:16972788
  • Massa V, Wlodarczyk BJ, Giavini E, Finnell RH. 2006. Myo-inositol enhances teratogenicity of valproic acid in the mouse. Birth Defects Res A Clin Mol Teratol 76(3):200-204. PMID:16511884
  • Matson CW, Lambert MM, McDonald TJ, Autenrieth RL, Donnelly KC, Islamzadeh A, Politov DI, Bickham JW. 2006. Evolutionary toxicology: population-level effects of chronic contaminant exposure on the marsh frogs (Rana ridibunda) of Azerbaijan. Environ Health Perspect 114(4):547-552. PMID:16581544
  • Meador KJ, Baker G, Finnell RH, Kalayjian LA, Liporace JD, Loring DW, Mawer G, Pennell PB, Smith JC, Wolff MC. 2006. In utero antiepileptic drug exposure: fetal death and malformations. Neurology 67(3):407-412. PMID:16894099
  • Mitchell LE, Finnell RH, Whitehead A. 2006. Aetiology and Prevention of Spina Bifida. Chapter 9 in: Recent Advances in Pediatrics 23. Royal Society of Medicine Press, London, England. pp.12.
  • Pei L, Zhu H, Zhu J, Ren A, Finnell RH, Li Z. 2006. Genetic variation of infant reduced folate carrier (A80G) and risk of orofacial defects and congenital heart defects in China. Ann Epidemiol 16(5):352-356. doi:10.1016/j.annepidem.2005.02.014 PMID:16019224
  • Ramos KS, Falahatpisheh MH, Nanez A, He Q. 2006. Modulation of biological regulatory networks during nephrogenesis. J Mol Biol 38(4):677-683. doi:10.1080/03602530600959532 PMID:17145695
  • Safe SH. 2006. Polychlorinated biphenyls. In: Environmental and Occupational Medicine, 4th Edition. Lippincott-Raven Publishers, Philadelphia, PA.
  • Safe SH, Papineni S. 2006. The role of xenoestrogenic compounds in the development of breast cancer. Trends Pharmacol Sci 27(8):447-454. PMID:16822555
  • Sobol E, Yagen B, White HS, Wilcox KS, Lamb JG, Pappo O, Wlodarczyk BJ, Finnell RH, Bialer M. 2006. Preclinical evaluation of 2,2,3,3-tetramethylcyclopropanecarbonyl-urea, a novel, second generation to valproic acid, antiepileptic drug. Neuropharmacology 51(4):933-946. doi:10.1016/j.neuropharm.2006.06.006 PMID:16890251
  • Tiffany-Castiglioni E, Hong SJ, Qian Y, Tang Y, Donnelly KC. 2006. In vitro models for assessing neurotoxicity of mixtures. Neurotoxicology 27(5):835-839. PMID:16843529
  • Wlodarczyk BJ, Cabrera RM, Hill DS, Bozinov D, Zhu H, Finnell RH. 2006. Arsenic-induced gene expression changes in the neural tube of folate transport defective mouse embryos. Neurotoxicology 27(4):547-557. PMID:16620997
  • Wlodarczyk BJ, Tang LS, Triplett A, Aleman F, Finnell RH. 2006. Spontaneous neural tube defects in Splotch mice supplemented with selected micronutrients. Toxicol Appl Pharmacol 213(1):55-63. PMID:16226775
  • Zhang J, Zhu H, Yang W, Shaw GM, Lammer EJ, Finnell RH. 2006. Phosphatidylethanolamine N-methyltransferase (PEMT) gene polymorphisms and risk of spina bifida. American Journal of Medical Genetics Part A 140(7):785-789. PMID:16523512
  • Zhu H, Yang W, Lu W, Zhang J, Shaw GM, Lammer EJ, Finnell RH. 2006. A known functional polymorphism (Ile120Val) of the human PCMT1 gene and risk of spina bifida. Mol Genet Metab 87(1):66-70. PMID:16256389
  • Zhu J, Ren A, Hao L, Pei L, Liu J, Zhu H, Li S, Finnell RH, Li Z. 2006. Variable contribution of the MTHFR C677T polymorphism to non-syndromic cleft lip and palate risk in China. American Journal of Medical Genetics Part A 140(6):551-557. PMID:16470725

2005

  • Abraham MH, Autenrieth RL, Dimitriou-Christidis P. 2005. The estimation of physicochemical properties of methyl and other alkyl naphthalenes. J Environ Monit 7(5):445-449. PMID:15877164
  • Afriyie-Gyawu E, Mackie J, Dash B, Wiles MC, Taylor JF, Huebner HJ, Tang L, Guan H, Wang J, Phillips TD. 2005. Chronic toxicological evaluation of dietary NovaSil clay in Sprague-Dawley rats. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 22(3):259-169. PMID:16019794
  • Afriyie-Gyawu E, Wiles MC, Richardson MB, Fickey C, Phillips TD. 2005. Prevention of zearalenone-induced hyperestrogenism in prepubertal mice. J Toxicol Environ Health A 68(5):353-368. PMID:15799627
  • Custer CM, Custer TW, Rosiu CJ, Melancon MJ, Bickham JW, Matson CW. 2005. Exposure and effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in tree swallows (Tachycineta bicolor) nesting along the Woonasquatucket River, Rhode Island, USA. Environ Toxicol Chem 24(1):93-109. PMID:15683172
  • Donnelly KC, Huebner HJ, Claxton LD, Calvin J, Vos GA, Cizmas LH, He L. 2005. Biodegradation of simple chemical mixtures in soil. Environ Toxicol Chem 24(11):2839-2845. PMID:16398121
  • Lu W, Volcik K, Zhu H, Wen S, Shaw GM, Lammer EJ, Finnell RH. 2005. Genetic variation in the proto-oncogene SKI and risk for orofacial clefting. Mol Genet Metab 86(3):412-416. doi:10.1016/j.ymgme.2005.06.003 PMID:16054854
  • Massa V, Cabrera RM, Menegola E, Giavini E, Finnell RH. 2005. Valproic acid-induced skeletal malformations: associated gene expression cascades. Pharmacol Toxicol 15(11):787-800. PMID:16220111
  • Matson CW, Palatnikov GM, Islamzadeh A, McDonald TJ, Autenrieth RL, Donnelly KC, Bickham JW. 2005. Chromosomal Damage in two species of aquatic turtles (Emys orbicularis and Mauremys caspica) inhabiting contaminated sites in Azerbaijan. Ecotoxicology 14(5):513-525. PMID:16220359
  • Matson CW, Palatnikov GM, McDonald TJ, Autenrieth RL, Donnelly KC, Anderson TA, Canas JE, Islamzadeh A, Bickham JW. 2005. Patterns of genotoxicity and contaminant exposure: evidence of genomic instability in the marsh frog (Rana Ridibunda) of Sumgayit, Azerbaijan. Environ Toxicol Chem 24:2055-2064. PMID:16152979
  • Ottinger SE, Barhoumi R, McKenzie KS, McDonald TJ, Burghardt RC, Huebner HJ, Phillips TD. 2005. FIA/MS analysis of temporally ozonated benzo[a]pyrene and pyrene and their reaction products: inhibition of gap junction-mediated intercellular communication. Chemosphere 60(8):1025-1033. doi:10.1016/j.chemosphere.2005.01.025 PMID:15993149
  • Qian Y, Zheng Y, Abraham L, Ramos KS, Tiffany-Castiglioni E. 2005. Differential profiles of copper-induced ROS generation in human neuroblastoma and astrocytoma cells. Brain Res 134(2):323-332. doi:10.1016/j.molbrainres.2004.11.004 PMID:15836927
  • Qian Y, Zheng Y, Ramos KS, Tiffany-Castiglioni E. 2005. The involvement of copper transporter in lead-induced oxidative stress in astroglia. Neurochem Res 30(4):429-438. PMID:16076012
  • Safe SH. 2005. Clinical correlates of environmental endocrine disruptors. Trends in Endocrinology and Metabolism 16(4):139-144. PMID:15860409
  • Spiegelstein O, Cabrera RM, Finnell RH. 2005. Functional Genomics and Proteomics in Developmental and Reproductive Toxicology. In: Developmental and Reproductive Toxicology, A Practical Approach. Second Edition. pp.621-646.
  • Spiegelstein O, Gould A, Wlodarczyk BJ, Tsie M, Lu X, Le X, Troen A, Selhub J, Piedrahita JA, Salbaum JM, Kappen C, Melnyk SB, James S, Finnell RH. 2005. Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies. Toxicol Appl Pharmacol 203(1):18-26. PMID:15694460
  • Spiegelstein O, Lu X, Le X, Troen A, Selhub J, Melnyk SB, James S, Finnell RH. 2005. Effects of dietary folate intake and folate binding protein-2 (Folbp2) on urinary speciation of sodium arsenate in mice. Environ Toxicol Pharmacol 19(1):1-7. doi:10.1016/j.etap.2004.01.007 PMID:21783456
  • Tang LS, Santillano DR, Miranda RC, Finnell RH. 2005. Role of Folbp1 in the regional regulation of apoptosis and cell proliferation in the developing neural tube and craniofacies. American Journal of Medical Genetics Part C: Seminars in Medical Genetics 135C(1):48-58. PMID:15800851
  • Wang J, Luo H, Billam M, Wang Z, Guan H, Tang L, Goldston T, Afriyie-Gyawu E, Lovett C, Griswold J, Brattin B, Taylor RJ, Huebner HJ, Phillips TD. 2005. Short-term safety evaluation of processed calcium montmorillonite clay (NovaSil) in humans. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 22(3):270-279. PMID:16019795
  • Wiles MC, Huebner HJ, McDonald TJ, Donnelly KC, Phillips TD. 2005. Matrix-immobilized organoclay for the sorption of polycyclic aromatic hydrocarbons and pentachlorophenol from groundwater. Chemosphere 59(10):1455-1464. PMID:15876388

2004

  • Bickham JW, Patton JC, Schlitter DA, Rautenbach IL, Honeycutt RL. 2004. Molecular phylogenetics, karyotypic diversity, and partition of the genus Myotis (Chiroptera: Vespertilionidae). Mol Phylogenet Evol 33(2):333-338. PMID:15336668
  • Bickham JW, Theodorakis CW. 2004. Molecular characterization of contaminant-indicative RAPD markers. Ecotoxicology 13(4):303-309. PMID:15344511
  • Cizmas LH, Zhou GD, Safe SH, McDonald TJ, Zhu L, Donnelly KC. 2004. Comparative in vitro and in vivo genotoxicities of 7H-benzo[c]fluorene, manufactured gas plant residue (MGP), and MGP fractions. Environ Mol Mutagen 43(3):159-168. doi:10.1002/em.20011 PMID:15065203
  • Donnelly KC, Lingenfelter R, Cizmas LH, Falahatpisheh MH, Qian Y, Tang Y, Garcia SS, Ramos KS, Tiffany-Castiglioni E, Mumtaz MM. 2004. Toxicity assessment of complex mixtures remains a goal. Environ Toxicol Pharmacol 18(2):135-141. doi:10.1016/j.etap.2004.03.013 PMID:21782742
  • Falahatpisheh MH, Kerzee JK, Metz RP, Donnelly KC, Ramos KS. 2004. Inducible cytochrome P450 activities in renal glomerular mesangial cells: biochemical basis for antagonistic interactions among nephrocarcinogenic polycyclic aromatic hydrocarbons. J Carcinog 3(1):12. doi:10.1186/1477-3163-3-12 PMID:15315710 PMCID:PMC516019
  • Finnell RH, Shaw GM, Lammer EJ, Brandl KL, Carmichael SL, Rosenquist TH. 2004. Gene-nutrient interactions: importance of folates and retinoids during early embryogenesis. Toxicol Appl Pharmacol 198(2):75-85. PMID:15236946
  • Herrera P, Burghardt RC, Huebner HJ, Phillips TD. 2004. The efficacy of sand-immobilized organoclays as filtration bed materials for bacteria. Food Microbiol 21(1):1-10.
  • Jiang J, Dean D, Burghardt RC, Parrish AR. 2004. Disruption of cadherin/catenin expression, localization, and interactions during HgCl2-induced nephrotoxicity. Toxicol Sci 80(1):170-182. PMID:15084754
  • Matson CW, Franson JC, Hollman T, Kilpi M, Hario M, Flint PL, Bickham JW. 2004. Evidence of chromosomal damage in common eiders (Somateria mollissima) from the Baltic Sea. Mar Pollut Bull 49(11-12):1066-1071. PMID:15556194
  • Norman RS, Moeller P, McDonald TJ, Morris PJ. 2004. Effect of pyocyanin on a crude-oil-degrading microbial community. Appl Environ Microbiol 70(7):4004-4011. doi:10.1128/AEM.70.7.4004-4011.2004 PMID:15240276 PMCID:PMC444818
  • Pimpukdee K, Kubena LF, Bailey CA, Huebner HJ, Afriyie-Gyawu E, Phillips TD. 2004. Aflatoxin-induced toxicity and depletion of hepatic vitamin A in young broiler chicks: protection of chicks in the presence of low levels of NovaSil PLUS in the diet. Poultry Science 83(5):737-744. PMID:15141830
  • Reeves WR, McDonald TJ, Cizmas LH, Donnelly KC. 2004. Partitioning and desorption behavior of polycyclic aromatic hydrocarbons from disparate sources. Sci Total Environ 332(1-3):183-192. PMID:15336901
  • Spiegelstein O, Cabrera RM, Bozinov D, Wlodarczyk BJ, Finnell RH. 2004. Folate-regulated changes in gene expression in the anterior neural tube of folate binding protein-1 (Folbp1)-deficient murine embryos. Neurochem Res 29(6):1105-1112. PMID:15176467
  • Spiegelstein O, Mitchell LE, Merriweather MY, Wicker NJ, Zhang Q, Lammer EJ, Finnell RH. 2004. Embryonic development of folate binding protein-1 (Folbp1) knockout mice: Effects of the chemical form, dose, and timing of maternal folate supplementation. Dev Dyn 231(1):221-231. doi:10.1002/dvdy.20107 PMID:15305303
  • Tang LS, Santillano DR, Miranda RC, Finnell RH. 2004. Developmental consequences of abnormal folate transport during murine heart morphogenesis. Birth Defects Res A Clin Mol Teratol 70(7):449-458. PMID:15259034
  • Wiles MC, Huebner HJ, Afriyie-Gyawu E, Taylor RJ, Bratton GR, Phillips TD. 2004. Toxicological evaluation and metal bioavailability in pregnant rats following exposure to clay minerals in the diet. J Toxicol Environ Health A 67(11):863-874. doi:10.1080/15287390490425777 PMID:15205041
  • Zhou GD, Randerath K, Donnelly KC, Jaiswal AK. 2004. Effects of NQO1 deficiency on levels of cyclopurines and other oxidative DNA lesions in liver and kidney of young mice. Int J Cancer 112(5):877-883. PMID:15386390

2003

  • Abdelrahim M, Safe SH. 2003. Aryl hydrocarbon receptor gene silencing with small inhibitory RNA differentially modulates Ah-responsiveness in MCF-7 and HepG2 cancer cells. Mol Pharmacol 63(6):1373-1381. PMID:12761348
  • Ake CL, Wiles MC, Huebner HJ, McDonald TJ, Cosgriff D, Richardson MB, Donnelly KC, Phillips TD. 2003. Porous organoclay composite for the sorption of polycyclic aromatic hydrocarbons and pentachlorophenol from groundwater. Chemosphere 51(9):835-844. doi:10.1016/S0045-6535(03)00040-7 PMID:12697173
  • Bickham JW, Matson CW, Islamzadeh A, Rowe GT, Donnelly KC, Swartz CD, Autenrieth RL, McDonald TJ, Politov DI, Wickliffe JK, Palatnikov GM, Mekhtiev AA, Kasimov R, Rogers WJ. 2003. Editorial: the unknown environmental tragedy in Sumgayit, Azerbaijan. Ecotoxicology 12(6):505-508. PMID:14680331
  • Bingham AK, Phillips TD, Bauer JE. 2003. Potential for dietary protection against the effects of aflatoxins in animals. J Am Vet Med Assoc 222(5):591-596. doi:10.2460/javma.2003.222.591 PMID:12619837
  • Castro-Rivera E, Safe SH. 2003. 17 beta-estradiol- and 4-hydroxytamoxifen-induced transactivation in breast, endometrial and liver cancer cells is dependent on ER-subtype, cell and promoter context. Psychiatr Pol 84:23-31. PMID:12648521
  • Cizmas LH, Barhoumi R, Burghardt RC, Reeves WR, He L, McDonald TJ, Donnelly KC. 2003. A comparison of two methods for fractionating complex mixtures in preparation for toxicity analysis. J Toxicol Environ Health A 66(14):1351-1370. PMID:12851116
  • Dimitriou-Christidis P, Harris BC, McDonald TJ, Reese ED, Autenrieth RL. 2003. Estimation of selected physicochemical properties for methylated naphthalene compounds. Chemosphere 52(5):869-881. doi:10.1016/S0045-6535(03)00288-1 PMID:12757788
  • Falahatpisheh MH, Ramos KS. 2003. Ligand-activated Ahr signaling leads to disruption of nephrogenesis and altered Wilms' tumor suppressor mRNA splicing. Oncogene 22(14):2160-2171. PMID:12687018
  • Finnell RH, Gould A, Spiegelstein O. 2003. Pathobiology and genetics of neural tube defects. Epilepsia 44:14-23Suppl.3. PMID:12790882
  • Hong MS, Hong SJ, Barhoumi R, Burghardt RC, Donnelly KC, Wild JR, Venkatraj V, Tiffany-Castiglioni E. 2003. Neurotoxicity induced in differentiated SK-N-SH-SY5Y human neuroblastoma cells by organophosphorus compounds. Toxicol Appl Pharmacol 186(2):110-118. PMID:12639502
  • Huebner HJ, Phillips TD. 2003. Clay-based affinity probes for selective cleanup and determination of aflatoxin B1 using nanostructured montmorillonite on quartz. J AOAC Int 86(3):534-539. PMID:12852572
  • Kuliev G, Bickham JW. 2003. Karyotypes of four species of rodents. Tex J Sci 55:271-277.
  • LaRivere D, Autenrieth RL, Bonner JS. 2003. Redox dynamics during recovery of an oil-impacted estuarine wetland. Water Res 37(14):3307-3318. PMID:12834723
  • Lum KT, Huebner HJ, Li Y, Phillips TD, Raushel FM. 2003. Organophosphate nerve agent toxicity in Hydra attenuata. Chem Res Toxicol 16(8):953-957. PMID:12924922
  • Meek IB, Peplow AW, Ake CL, Phillips TD, Beremand MN. 2003. Tri1 encodes the cytochrome P450 monooxygenase for C-8 hydroxylation during trichothecene biosynthesis in Fusarium sporotrichioides and resides upstream of another new Tri gene. Appl Environ Microbiol 69(3):1607-1613. PMID:12620849
  • Mills MA, Bonner JS, McDonald TJ, Page CA, Autenrieth RL. 2003. Intrinsic bioremediation of a petroleum-impacted wetland. Mar Pollut Bull 46(7):887-899. PMID:12837307
  • Mueller DC, Bonner JS, McDonald SJ, Autenrieth RL, Donnelly KC, Lee K, Doe K, Anderson J. 2003. The use of toxicity bioassays to monitor the recovery of oiled wetland sediments. Environ Toxicol Chem 22(9):1945-1955. PMID:12959519
  • Peplow AW, Meek IB, Wiles MC, Phillips TD, Beremand MN. 2003. Tri16 is required for esterification of position C-8 during trichothecene mycotoxin production by Fusarium sporotrichioides. Appl Environ Microbiol 69(10):5935-5940. PMID:14532047
  • Phillips TD, Lemke SL, Grant PG. 2003. Characterization of clay-based enterosorbents for the prevention of aflatoxicosis. In: Advances in Experimental Medicine and Biology. Kluwer Academic/Plenum Publishers, NY. pp.157-173.
  • Qian Y, Tiffany-Castiglioni E. 2003. Lead-induced endoplasmic reticulum (ER) stress responses in the nervous system. Neurochem Res 28:153-162. PMID:12587673
  • Qin C, Burghardt RC, Smith RL, Wormke M, Stewart J, Safe SH. 2003. Peroxisome proliferator-activated receptor gamma agonists induce proteasome-dependent degradation of cyclin D1 and estrogen receptor alpha in MCF-7 breast cancer cells. Cancer Res 63(5):958-964. PMID:12615709
  • Safe SH. 2003. Toxicology and risk assessment of POPs. In: The Handbook of Environmental Chemistry. Springer Verlag, Heidelberg, Germany. pp.224-235.
  • Safe SH, Wormke M. 2003. Inhibitory aryl hydrocarbon receptor-estrogen receptor alpha cross-talk and mechanisms of action. Chem Res Toxicol 16(7):807-816. doi:10.1021/tx034036r PMID:12870882
  • Spiegelstein O, Lu X, Le X, Troen A, Selhub J, Melnyk SB, James S, Finnell RH. 2003. Effects of dietary folate intake and folate binding protein-1 (Folbp1) on urinary speciation of sodium arsenate in mice. Toxicol Lett 145(2):167-174. doi:10.1016/S0378-4274(03)00307-2 PMID:14581169
  • Spiegelstein O, Lu X, Le X, Troen A, Selhub J, Melnyk SB, James S, Finnell RH. 2003. Urinary speciation of sodium arsenate in folate receptor knockout mice. In: Arsenic Exposure and Health Effects IV. Elsevier, New York, NY. pp.335-342.
  • Swartz CD, Donnelly KC, Islamzadeh A, Rowe GT, Rogers WJ, Palatnikov GM, Mekhtiev AA, Kasimov R, McDonald TJ, Wickliffe JK, Presley BJ, Bickham JW. 2003. Chemical contaminants and their effects in fish and wildlife from the industrial zone of Sumgayit, Republic of Azerbaijan. Ecotoxicology 12(6):509-521. PMID:14680332
  • Tang LS, Finnell RH. 2003. Neural and orofacial defects in Folbp1 knockout mice. Birth Defects Res A Clin Mol Teratol 67(4):209-218. PMID:12854656
  • Tang Y, Donnelly KC, Tiffany-Castiglioni E, Mumtaz MM. 2003. Neurotoxicity of polycyclic aromatic hydrocarbons and simple chemical mixtures. J Toxicol Environ Health A 66(10):919-940. PMID:12825237
  • Tiffany-Castiglioni E. 2003. In Vitro Neurotoxicology. In: Methods in Pharmacology and Toxicology: In Vitro Neurotoxicology: Principles and Challenges. Humana Press Inc., pp.1-28.
  • Tiffany-Castiglioni E, Qian Y. 2003. Cell-Type Specific Responses of the Nervous System to Lead. In: Methods in Pharmacology and Toxicology: In Vitro Neurotoxicology: Principles and Challenges. Humana Press Inc., pp.151-186.
  • Wormke M, Stoner M, Saville B, Walker K, Abdelrahim M, Burghardt RC, Safe SH. 2003. The aryl hydrocarbon receptor mediates degradation of estrogen receptor alpha through activation of proteasomes. Mol Cell Biol 23(6):1842-1855. PMID:12612060
  • Zhang S, Qin C, Safe SH. 2003. Flavonoids as aryl hydrocarbon receptor agonists/antagonists: effects of structure and cell context. Environ Health Perspect 111(16):1877-1882. PMID:14644660
  • Zhu H, Wicker NJ, Shaw GM, Lammer EJ, Hendricks K, Suarez L, Canfield M, Finnell RH. 2003. Homocysteine remethylation enzyme polymorphisms and increased risks for neural tube defects. Mol Genet Metab 78(3):216-221. PMID:12649067

2002

  • Abdelrahim M, Samudio I, Smith, III R, Burghardt RC, Safe SH. 2002. Small inhibitory RNA duplexes for Sp1 mRNA block basal and estrogen-induced gene expression and cell cycle progression in MCF-7 breast cancer cells. J Biol Chem 277(32):28815-28822. PMID:12052832
  • Barhoumi R, Mouneimne Y, Awooda I, Safe SH, Donnelly KC, Burghardt RC. 2002. Characterization of calcium oscillations in normal and benzo[a]pyrene-treated clone 9 cells. Toxicol Sci 68(2):444-450. PMID:12151640
  • Finnell RH, Gelineau-van Waes J, Eudy JD, Rosenquist TH. 2002. Molecular basis of environmentally enduced birth defects. Annu Rev Pharmacol Toxicol 42:181-208. PMID:11807170
  • Finnell RH, Junker W, Wadman L, Cabrera RM. 2002. Gene expression profiling within the developing neural tube. Neurochem Res 27(10):1165-1180. PMID:12462415
  • Finnell RH, Spiegelstein O, Wlodarczyk BJ, Triplett A, Pogribny IP, Melnyk SB, James JS. 2002. DNA methylation in Folbp1 knockout mice supplemented with folic acid during gestation. J Nutr 132(8):2457S-2461SSuppl.S. PMID:12163711
  • Frontera-Suau R, Bost FD, McDonald TJ, Morris PJ. 2002. Aerobic biodegradation of hopanes and other biomarkers by crude oil-degrading enrichment cultures. Environ Sci Technol 36(21):4585-4592. PMID:12433168
  • Gefrides LA, Bennett GB, Finnell RH. 2002. Effects of folate supplementation on the risk of spontaneous and induced neural tube defects in Splotch mice. Birth Defects Res A Clin Mol Teratol 65(2):63-69. doi:10.1002/tera.10019 PMID:11857507
  • Mealey KL, Barhoumi R, Burghardt RC, Safe SH, Kochevar DT. 2002. Doxycycline induces expression of P glycoprotein in MCF-7 breast carcinoma cells. Antimicrobial Agents and Chemotherapy 46(3):755-761. PMID:11850258
  • Page CA, Bonner JS, McDonald TJ, Autenrieth RL. 2002. Behavior of a chemically dispersed oil in a wetland environment. Water Res 36(15):3821-3833. PMID:12369528
  • Parrish AR, Alejandro NF, Bral CM, Kerzee JK, Bowes RC, Ramos KS. 2002. Characterization of glomerular cell phenotypes following repeated cycles of benzo[a]pyrene injury in vitro. Biochem Pharmacol 64(1):31-39. PMID:12106603
  • Qin C, Nguyen T, Stewart J, Burghardt RC, Safe SH. 2002. Estrogen up-regulation of p53 gene expression in MCF-7 breast cancer cells is mediated, by calmodulin kinase IV-dependent activation of a nuclear factor kappa B/CCAAT-binding transcription factor-1 complex. Mol Endocrinol 16(8):1793-1809. PMID:12145335
  • Reese ED, Harris BC, Dimitriou-Christidis P, Autenrieth RL, Donnelly KC, McDonald TJ. 2002. Applicability of Toxic Equivalency Factors (TEFs) For Risk Assessment of Complex Mixtures. In: Proceedings of the Society of Environmental Toxicology and Chemistry 23rd Annual Meeting in North America. Salt Lake City, UT.
  • Ress NB, Donnelly KC, George S. 2002. The effect of pentachlorophenol on DNA adduct formation in p53 wild-type and knockout mice exposed to benzo[a]pyrene. Cancer Lett 178(1):11-17. PMID:11849736
  • Safe SH. 2002. Environmental estrogens: roles in male reproductive tract problems and in breast cancer. Rev Environ Health 17(4):253-262. PMID:12611468
  • Safe SH. 2002. Exposure to POPs and other congeners. In: Biomarkers of Environmentally Associated Disease: Technologies, Concepts, and Perspectives. CRC Press Company, Boca Raton, FL. pp.455-470.
  • Safe SH, Pallaroni L, Yoon K, Gaido KW, Ross S, McDonnell DP. 2002. Problems for risk assessment of endocrine-active estrogenic compounds. Environ Health Perspect 110(Suppl6):925-929. PMID:12634121
  • Safe SH, Yoon K, Castro-Rivera E, Pallaroni L, Gaido KW. 2002. Ligand structure-dependent activation of the estrogen receptor by xenoestrogens. Front Biosci (Landmark Ed)
  • Stoner M, Saville B, Wormke M, Dean D, Burghardt RC, Safe SH. 2002. Hypoxia induces proteasome-dependent degradation of estrogen receptor a in ZR-75 breast cancer cells. Mol Endocrinol 16(10):2231-2242. PMID:12351689

2001

  • Ake CL, Mayura K, Huebner HJ, Bratton GR, Phillips TD. 2001. Development of porous clay-based composites for the sorption of lead from water. J Toxicol Environ Health A 63(6):459-475. PMID:11482800
  • Bordelon NR, Donnelly KC, George S. 2001. Pentachlorophenol potentiates benzo[a]pyrene DNA adduct formation in adult but not infant B6C3F1 male mice. Environ Mol Mutagen 37(2):164-172. PMID:11246223
  • Bost FD, Frontera-Suau R, McDonald TJ, Peters KE, Morris PJ. 2001. Aerobic biodegradation of hopanes and horhopanes in Venezuelan crude oils. Organic Geochemistry 32:105-114.
  • Duan R, Xie W, Burghardt RC, Safe SH. 2001. Estrogen receptor-mediated activation of the serum response element in MCF-7 cells through MAPK-dependent phosphorylation of Elk-1. J Biol Chem 276(15):11590-11598. doi:10.1074/jbc.M005492200 PMID:11145955
  • Falahatpisheh MH, Donnelly KC, Ramos KS. 2001. Antagonistic interactions among nephrotoxic polycyclic aromatic hydrocarbons. J Toxicol Environ Health A 62(7):543-560. PMID:11289703
  • Lee J, Safe SH. 2001. Involvement of a post-transcriptional mechanism in the inhibition of CYP1A1 expression by resveratrol in breast cancer cells. Biochem Pharmacol 62(8):1113-1124. doi:10.1016/S0006-2952(01)00763-8 PMID:11597580
  • Lemke SL, Mayura K, Reeves WR, Wang N, Fickey C, Phillips TD. 2001. Investigation of organophilic montmorillonite clay inclusion in zearalenone-contaminated diets using the mouse uterine weight bioassay. J Toxicol Environ Health A 62(4):243-258. doi:10.1080/009841001459405 PMID:11245394
  • Lemke SL, Ottinger SE, Ake CL, Mayura K, Phillips TD. 2001. Deamination of fumonisin B1 and biological assessment of reaction product toxicity. Chem Res Toxicol 14(1):11-15. PMID:11170503
  • Lemke SL, Ottinger SE, Mayura K, Ake CL, Pimpukdee K, Wang N, Phillips TD. 2001. Development of a multi-tiered approach to the in vitro prescreening of clay-based enterosorbents. Animal Feed Science and Technology 93(1-2):17-29. doi:10.1016/S0377-8401(01)00272-3
  • McDougal A, Gupta MS, Morrow D, Ramamoorthy K, Lee J, Safe SH. 2001. Methyl-substituted diindolylmethanes as inhibitors of estrogen-induced growth of T47D cells and mammary tumors in rats. Breast Cancer Res Treat 66(2):147-157. PMID:11437101
  • Randerath K, Zhou GD, Somers RL, Robbins JH, Brooks PJ. 2001. A 32P-postlabeling assay for the oxidative DNA lesion 8,5'-cyclo-2'-deoxyadenosine in mammalian tissues: evidence that four type II I-compounds are dinucleotides containing the lesion in the 3' nucleotide. J Biol Chem 276(38):36051-36057. doi:10.1074/jbc.M105472200 PMID:11454870
  • Reese ED, Harris BC, Dimitriou-Christidis P, Autenrieth RL, Donnelly KC, McDonald TJ. 2001. Risk Assessment of Complex Mixtures: Development of Toxic Equivalency Factors to Improve Toxicity Assessment. In: Proceedings of the Seventh International Congress on Combustion By-Products: Origins, Fate, and Health Effects. Research Triangle Park, NC.
  • Reeves WR, Barhoumi R, Burghardt RC, Lemke SL, Mayura K, McDonald TJ, Phillips TD, Donnelly KC. 2001. Evaluation of methods for predicting the toxicity of polycyclic aromatic hydrocarbon mixtures. Environ Sci Technol 35(8):1630-1636. doi:10.1021/es001689a PMID:11329713
  • Reeves WR, McDonald TJ, Bordelon NR, George S, Donnelly KC. 2001. Impacts of aging on in vivo and in vitro measurements of soil-bound polycyclic aromatic hydrocarbon availability. Environ Sci Technol 35(8):1637-1643. PMID:11329714
  • Rosenquist TH, Finnell RH. 2001. Genes, folate and homocysteine in embryonic development. Proceedings of the Nutrition Society 60(1):53-61. PMID:11310424
  • Safe SH, McDougal A, Gupta MS, Ramamoorthy K. 2001. Selective Ah receptor modulators (SAhRMs): progress towards development of a new class of inhibitors of breast cancer growth. Journal of Women's Cancer 3:37-45.
  • Safe SH, Pallaroni L, Yoon K, Gaido KW, Ross S, Saville B, McDonnell DP. 2001. Toxicology of environmental estrogens. Reproduction, Fertility and Development 13:307-315. PMID:11800169
  • Samudio I, Vyhlidal C, Wang F, Stoner M, Chen I, Kiadde M, Barhoumi R, Burghardt RC, Safe SH. 2001. Transcriptional activation of deoxyribonucleic acid polymerase alpha gene expression in MCF-7 cells by 17 beta-estradiol. Endocrinology 142(3):1000-1008. PMID:11181512
  • Washburn KS, Donnelly KC, Huebner HJ, Burghardt RC, Sewall TC, Claxton LD. 2001. A study of 2,4,6-trinitrotoluene inhibition of benzo[a]pyrene uptake and activation in a microbial mutagenicity assay. Chemosphere 44(8):1703-1709. PMID:11534902
  • Waters KM, Safe SH, Gaido KW. 2001. Differential gene expression in response to methoxychlor and estradiol through ERalpha, ERbeta, and AR in reproductive tissues of female mice. Toxicol Sci 63:47-56. PMID:11509743
  • Wlodarczyk BJ, Spiegelstein O, Gelineau-van Waes J, Vorce RL, Lu X, Le C, Finnell RH. 2001. Arsenic-induced congenital malformations in genetically susceptible folate binding protein-2 knockout mice. Toxicol Appl Pharmacol 177(3):238-246. PMID:11749123
  • Yoon K, Pallaroni L, Stoner M, Gaido KW, Safe SH. 2001. Differential activation of wild-type and variant forms of estrogen receptor alpha by synthetic and natural estrogenic compounds using a promoter containing three estrogen-responsive elements. Psychiatr Pol 78(1):25-32. PMID:11530281

2000

  • Alejandro NF, Parrish AR, Bowes RC, Burghardt RC, Ramos KS. 2000. Phenotypic profiles of cultured glomerular cells following repeated cycles of hydrocarbon injury. Kidney International 57:1571-1580. PMID:10760092
  • Barhoumi R, Mouneimne Y, Ramos KS, Safe SH, Phillips TD, Centonze VE, Ainley C, Gupta MS, Burghardt RC. 2000. Analysis of Benzo[a]pyrene partitioning and cellular homeostasis in a rat liver cell line. Toxicol Sci 53:264-270. PMID:10696774
  • Bordelon NR, Donnelly KC, King LC, Wolf DC, Reeves WR, George S. 2000. Bioavailability of genotoxic compounds in coal tar contaminated soils in Fisher 344 rats. Toxicol Sci 56(1):37-48. doi:10.1093/toxsci/56.1.37 PMID:10869452
  • Cho T, Wild JR, Donnelly KC. 2000. Utility of organophosphorus hydrolase for the remediation of mutagenicity of methyl parathion. Environ Toxicol Chem 19(8):2022-2028.
  • Eudy JD, Spiegelstein O, Barber RC, Wlodarczyk BJ, Talbot J, Finnell RH. 2000. Identification and characterization of the human and mouse SLC19A3 gene: a novel member of the reduced folate family of micronutrient transporter genes. Mol Genet Metab 71(4):581-590. PMID:11136550
  • Gaido KW, Maness SC, McDonnell DP, Dehal SS, Kupfer D, Safe SH. 2000. Interaction of methoxychlor and related compounds with estrogen receptor alpha and beta, and androgen receptor: structure-activity studies. Mol Pharmacol 58(4):852-858. PMID:10999957
  • Garcia S, Donnelly KC. 2000. Genotoxicity analysis of contaminated environmental media. In: Bioremediation and Land Reclamation: Tools to measure Success or Failure. John Wiley and Sons, Ltd, Sussex, United Kingdom.
  • Gelineau-van Waes J, Bennett GD, Barber RC, Wlodarczyk BJ, Shaw GM, Lammer EJ, Piedrahita JA, Eberwine JH, Finnell RH. 2000. Genetic Basis of Susceptibility to Environmentally-Induced Birth Defects. In: Toxicology for the Next Millennium. New York Academy of Sciences, New York, NY. pp.261-277.
  • Grishchenkov VG, Townsend RT, McDonald TJ, Autenrieth RL, Bonner JS, Boronin AM. 2000. Degradation of petroleum hydrocarbons by facultative anaerobic bacteria under aerobic and anaerobic condition. Process Biochemistry 35:889-896.
  • Herrera P, Burghardt RC, Phillips TD. 2000. Adsorption of Salmonella enteritidis by cetyl pyridinium exchanged montmorillonite clays. Vet Microbiol 74:259-272. PMID:10808094
  • Huebner HJ, Mayura K, Pallaroni L, Ake CL, Lemke SL, Phillips TD. 2000. Development and characterization of a carbon-based composite for reducing patulin levels in apple juice. J Food Prot 63(1):106-110. PMID:10643778
  • Kester MH, Bulduk S, Tibboel D, Meinl W, Glatt H, Falany CN, Coughtrie MW, Bergman A, Safe SH, Kuipper GG, Schuur AG, Brouwer A, Visser TJ. 2000. Potent inhibition of estrogen sulfotransferase by hydroxylated PCB metabolites: a novel pathway explaining the estrogenic activity of PCBs. Endocrinology 141(5):1897-1900. doi:10.1210/endo.141.5.7530 PMID:10803601
  • Lee J, Safe SH. 2000. Interactions of resveratrol and TCDD in human breast cancer cells. Organohalogen Compounds 49:277-280.
  • Legare ME, Hanneman WH, Barhoumi R, Burghardt RC, Tiffany-Castiglioni E. 2000. 2,3,7,8-tetrachlorodibenzo-p-dioxin alters hippocampal astroglia-neuronal gap junctional communication. Neurotoxicology 21(6):1109-1116. PMID:11233757
  • McDougal A, Gupta MS, Ramamoorthy K, Sun G, Safe SH. 2000. Inhibition of carcinogen-induced rat mammary tumor growth and other estrogen-dependent responses by symmetrical dihalo-substituted analogs of diindolylmethane. Cancer Lett 151(2):169-179. PMID:10738111
  • Mills MA, McDonald TJ, Bonner JS, Simon MA, Autenrieth RL. 2000. Method for quantifying the fate of petroleum in the environment. Chemosphere 39(14):2563-2582.
  • Page CA, Bonner JS, Sumner PL, McDonald TJ, Autenrieth RL, Fuller CB. 2000. Behavior of a chemically-dispersed oil and a whole oil on a near-shore environment. Water Res 34(9):2507-2516.
  • Ruan Y, Petersen MH, Wauson EM, Gelineau-van Waes J, Vorce RL, Finnell RH. 2000. Folic acid protects SWV/Fnn embryo fibroblasts against arsenic toxicity. Toxicol Lett 117:129-137. PMID:11087978
  • Safe SH. 2000. Bisphenol A and related endocrine disrupters. Toxicol Sci 56(2):251-252. PMID:10910979
  • Safe SH. 2000. Endocrine Disruptors: New Toxic Menace?. In: Earth Report 2000: Revisiting the True State of the Planet. McGraw Hill, New York, NY. pp.189-202.
  • Safe SH. 2000. Endocrine disruptors and human health - is there a problem: an update. Environ Health Perspect 108(6):487-493. PMID:10856020
  • Safe SH. 2000. Toxicology of persistent organic pollutants. European Journal of Lipid Science and Technology 102:52-53.
  • Safe SH. 2000. Xenoestrogens and human health. Is there a problem? The argument against. Progr. Environmental Science 21:21-30.
  • Spiegelstein O, Eudy JD, Finnell RH. 2000. Identification of two putative novel folate receptor genes in humans and mouse. Gene 258(1-2):117-125. PMID:11111049
  • Tag A, Hicks J, Garifullina G, Ake CL, Phillips TD, Beremand MN, Keller NP. 2000. G-protein signaling mediates differential production of toxic secondary metabolites. EMBO J 38(3):658-665. PMID:11069688
  • Yoon K, Pallaroni L, Ramamoorthy K, Gaido KW, Safe SH. 2000. Ligand structure-dependent differences in activation of estrogen receptor alpha in human HepG2 liver and U2 osteogenic cancer cell lines. Mol Cell Endocrinol 162(1-2):211-220. PMID:10854714
  • Zhou GD, Hernandez NS, Randerath E, Randerath K. 2000. Effects of different diets and dietary restriction on perinatal endogenous DNA adducts. Time dependence of oxidative and presumptive nonoxidative lesions. Mutat Res 447:137-147. PMID:10751597
  • Aggett PJ, Kuiper HA, eds. 2000. Reproductive effects: endocrine disruption. In: Risk Assessment in the Food Chain of Children. Nestle Nutrition Workshop Series, Paediatric Programme, Nestec Ltd. Vevey/Lippincott Williams & Wilkins, Philadelphia, PA.

1999

  • Chung F, Nath RG, Nagao M, Nishikawa A, Zhou GD, Randerath K. 1999. Endogenous formation and significance of 1,N2-propanodeoxyguanosine adducts. Mutat Res 424(1-2):71-81. PMID:10064851
  • Gaido KW, Leonard LS, Maness SC, Hall JM, McDonnell DP, Saville B, Safe SH. 1999. Differential interaction of the methoxychlor metabolite 2,2-bis-(p-hydroxyphenyl)-1,1,1-trichloroethane with estrogen receptors alpha and beta. Endocrinology 140(12):5746-5753. doi:10.1210/endo.140.12.7191 PMID:10579340
  • Huebner HJ, Lemke SL, Mayura K, Phillips TD, Ottinger SE. 1999. Molecular characterization of high affinity, high capacity clays for the equilibrium sorption of ergotamine. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 16(4):159-171. doi:10.1080/026520399284118 PMID:10560569
  • Lemke SL, Mayura K, Ottinger SE, McKenzie KS, Wang N, Fickey C, Kubena LF, Phillips TD. 1999. Assessment of the estrogenic effects of zearalenone after treatment with ozone utilizing the mouse uterine weight bioassay. J Toxicol Environ Health A 56(4):283-295. doi:10.1080/009841099158114 PMID:10706245
  • Mayura K, Huebner HJ, Dwyer MR, McKenzie KS, Donnelly KC, Kubena LF, Phillips TD. 1999. Multi-bioassay approach for assessing the potency of complex mixtures of polycyclic aromatic hydrocarbons. Chemosphere 38(8):1721-1732. PMID:10101844
  • Ottinger SE, Mayura K, Lemke SL, McKenzie KS, Wang N, Kubena LF, Phillips TD. 1999. Utilization of electrochemically generated ozone in the degradation and detoxification of benzo[a]pyrene. J Toxicol Environ Health A 56(8):565-583. doi:10.1080/009841099157511 PMID:10515574
  • Phillips TD. 1999. Dietary clay in the chemoprevention of aflatoxin-induced disease. Toxicol Sci 52:118-126. PMID:10630600
  • Ramamoorthy K, Gupta MS, Sun G, McDougal A, Safe SH. 1999. 3,3',4,4'-Tetrachlorobiphenyl exhibits antiestrogenic and antitumorigenic activity in the rodent uterus and mammary and in human breast cancer cells. Carcinogenesis 20:115-123. PMID:9934858
  • Ramamoorthy K, McDougal A, Safe SH. 1999. Structure-Ah receptor agonist/binding activity relationships of various chlorine-substituted diindolylmethane compounds. Organohalogen Compounds 42:363-367.
  • Randerath K, Randerath E, Zhou GD, Li D. 1999. Bulky endogenous DNA modifications (I-compounds) - possible structural origins and functional implications. Mutat Res 424:183-194. PMID:10064860
  • Randerath K, Randerath E, Zhou GD, Supungpong N, He L, McDonald TJ, Donnelly KC. 1999. Genotoxicity of complex PAH mixtures recovered from contaminated lake sediments as assessed by three different methods. Environ Mol Mutagen 33:303-312. PMID:10398378
  • Routh J, McDonald TJ, Grossman EL. 1999. Sedimentary organic matter sources and depositional environment in the Yegua formation (Brazos County, Texas). Organic Geochemistry 30:1437-1453.
  • Safe SH. 1999. Development and application of TEFs. Human and Ecological Risk Assessment: An International Journal 5:9-12.
  • Safe SH. 1999. Endocrine disruptors and human health - an update. Organohalogen Compounds 42:15-18.
  • Safe SH. 1999. Environmental estrogens. In: Encyclopedia of Reproduction, Vol 4. Academic Press, pp.1100-1103.
  • Simon MA, Bonner JS, McDonald TJ, Autenrieth RL. 1999. Bioaugmentation for the enhanced bioremediation of petroleum in a wetland. Polycyclic Aromatic Compounds 14&15:231-239.
  • Springman KR, Mayura K, McDonald TJ, Donnelly KC, Kubena LF, Phillips TD. 1999. Organoclay adsorption of wood-preserving waste from groundwater. Environ Toxicol Chem 71(1-2):247-259.
  • Zhou GD, Hernandez NS, Randerath E, Randerath K. 1999. Acute elevation by short-term dietary restriction or food deprivation of type I I-compound levels in rat liver DNA. Nutr Cancer 35:87-95. PMID:10624711
  • Marquardt H, Schafer SG, Welsch F, eds. 1999. Toxic equivalency factors and their use in hazard and risk assessment. In: Toxicology. Academic Press, San Diego, CA. pp.1191-1197.

1998

  • Ake, Jr., Connor K, Ramamoorthy K, Moore M, Wang F, Mustain M, Chen I, Zacharewski TR, Gillesby B, Joyeux A, Belaguer P, Gaido KW, Leonard LS, Maness SC, McDonnell DP. 1998. Estrogenic activity of hydroxylated polychlorinated biphenyls (PCBs) and their interaction. In: Hormonal Toxicants in Food, Proceedings. John Wiley, pp.200-207.
  • Burghardt RC, Barhoumi R, Sanborn BM, Andersen J. 1998. Oxytocin-induced Ca2+ responses in human myometrial cells. Biol Reprod 60:777-782. PMID:10084948
  • Clark KJ, Grant PG, Sarr AB, Belakere JR, Swaggerty CL, Phillips TD, Woode GN. 1998. An in vitro study of theaflavins extracted from black tea to neutralize bovine rotavirus and bovine coronavirus infections. Vet Microbiol 63(2-4):147-157. doi:10.1016/S0378-1135(98)00242-9 PMID:9850995
  • Clark KJ, Sarr AB, Grant PG, Phillips TD, Woode GN. 1998. In vitro studies on the use of clay, clay minerals and charcoal to adsorb bovine rotavirus and bovine coronavirus. Vet Microbiol 63:137-146. PMID:9850994
  • Donnelly KC, Claxton LD, Huebner HJ, Capizzi JL. 1998. Mutagenic interactions of model chemical mixtures. Chemosphere 37:1253-1261. PMID:9734320
  • Gaido KW, Dohme L, Wang F, Chen I, Blankvoort B, Ramamoorthy K, Safe SH. 1998. Comparative estrogenic activity of wine extracts and organochlorine pesticide residues in food. Environ Health Perspect 106S:1347-1351. PMID:9860891
  • Gould JC, Leonard LS, Maness SC, Wagner BL, Connor K, Zacharewski TR, Safe SH, McDonnell DP, Gaido KW. 1998. Bisphenol A interacts with the estrogen receptor α in a distinct manner from estradiol. Mol Cell Endocrinol 142:203-214. PMID:9783916
  • Grant PG, Lemke SL, Dwyer MR, Phillips TD. 1998. Modified Langmuir equation for S-shaped and multi-site isotherm plots. Langmuir 14:4292-4299.
  • Grant PG, Phillips TD. 1998. Isothermal adsorption of aflatoxin B1 on HSCAS clay. J Agric Food Chem 46:599-605. PMID:10554284
  • Gupta MS, Miggins J, Parrish AR, Womack J, Ramos KS, Rodriguez LV, Goldstein L, Holtzapple C, Stanker LH, Safe SH. 1998. Ah receptor-independent induction of CYP1A2 gene expression in genetically inbred mice. Environ Toxicol Pharmacol 5:205-213. PMID:21781866
  • Gupta MS, Ramamoorthy K, Safe SH. 1998. Antiestrogenic activity of 3,3',4,4'-tetrachlorobiphenyl and 3,3',4,4',5-pentachlorobiphenyl in T47D human breast cancer cells. Organohalogen Compounds 37:297-300.
  • Hoivik D, Safe SH. 1998. Polychlorinated biphenyls. In: Environmental and Occupational Medicine. Lippincott-Raven, Philadelphia, PA. pp.1205-1214.
  • Hutchinson RW, Barhoumi R, Miles J, Burghardt RC. 1998. Attenuation of gossypol cytotoxicity by cyclic AMP in a rat liver cell line. Toxicol Appl Pharmacol 151:311-318. PMID:9707507
  • Hutchinson RW, Ing NH, Burghardt RC. 1998. Induction of c-fos and cytochrome C oxidase subunits I and II by gossypol acetic acid in rat liver cells. Cell Biol Toxicol 14(6):391-399. PMID:9879931
  • Legare ME, Barhoumi R, Hebert E, Bratton GR, Burghardt RC, Tiffany-Castiglioni E. 1998. Analysis of Pb2+ entry into cultured astroglia. Toxicol Sci 46(1):90-100. doi:10.1006/toxs.1998.2492 PMID:9928672
  • Lemke SL, Grant PG, Phillips TD. 1998. Adsorption of zearalenone by organophilic montmorillonite clay. J Agric Food Chem 46:3789-3796.
  • Lopez Y, Keller NP, Sarr AB, Phillips TD, Cuero RG, Smith OD. 1998. Visual estimation of aflatoxin production in peanut with Aspergillus norsolorinic acid mutants. Peanut Science 25:92-99.
  • Mayura K, Abdel-Wahhab MA, McKenzie KS, Sarr AB, Edwards JF, Naguib K, Phillips TD. 1998. Prevention of maternal and developmental toxicity in rats via dietary inclusion of common aflatoxin sorbents: Potential for hidden risks. Toxicol Sci 41:175-182. PMID:9520353
  • McKenzie KS, Kubena LF, Denvir AJ, Rogers TD, Hitchens GD, Bailey RH, Harvey RB, Buckley SG, Phillips TD. 1998. Aflatoxicosis in turkey poults is prevented by treatment of naturally-contaminated corn with ozone generated by electrolysis. Poultry Science 77:1094-1102. PMID:9706072
  • Parrish AR, Fisher RL, Bral CM, Burghardt RC, Gandolfi A, Brendel K, Ramos KS. 1998. Benzo(a)pyrene-induced alterations in growth-related gene expression and signaling in precision-cut adult rat liver slices. Toxicol Appl Pharmacol 152:302-308. PMID:9852999
  • Ramamoorthy K, Navo M, Gupta MS, Safe SH. 1998. AhR-mediated antiestrogenicity of diindolylmethane and analogs in vivo and in vitro. Organohalogen Compounds 37:321-324.
  • Randerath K, Sriram P, Moorthy B, Aston JP, Baan R, Van den Berg PT, Booth ED, Watson WP. 1998. Comparison of immunoaffinity chromatography enrichment and nuclease P1 procedures for 32P-postlabelling analysis of PAH-DNA adducts. Chem Biol Interact 110(1-2):85-102. PMID:9566727
  • Safe SH. 1998. Development validation and problems with the toxic equivalency factor approach for risk assessment of dioxins and related compounds. J Anim Sci 76:134-141. PMID:9464894
  • Safe SH. 1998. Hazard and risk assessment of chemical mixtures using the toxic equivalency factor approach. Environ Health Perspect 106(supp.4):1051-1058. PMID:9703492
  • Safe SH. 1998. Interactions between hormones and chemicals in breast cancer. Annu Rev Pharmacol Toxicol 38:121-158. PMID:9597151
  • Safe SH, Connor K, Gaido KW. 1998. Methods for xenoestrogen testing. Toxicol Lett 102/103:661-666. PMID:10022332
  • Safe SH, Gaido KW. 1998. Phytoestrogens and anthropogenic estrogenic compounds. Environ Toxicol Chem 17:119-126.
  • Safe SH, Wilson CL. 1998. Health effects and risk assessment of halogenated aromatic hydrocarbons. Cent Eur J Public Health 6:113-116.
  • Thompson DC, Barhoumi R, Burghardt RC. 1998. Comparative toxicity of eugenol and its quinone methide metabolite in cultured liver cells using kinetic fluorescence bioassays. Toxicol Appl Pharmacol 149:55-63. PMID:9512727
  • Willett KL, Randerath K, Zhou GD, Safe SH. 1998. Inhibition of CYP1A1-dependent activity by the polynuclear aromatic hydrocarbon (PAH) fluoranthene. Biochem Pharmacol 55:831-839. PMID:9586956
  • Wilson CL, Safe SH. 1998. Mechanisms of ligand-induced aryl hydrocarbon receptor-mediated biochemical and toxic responses. Toxicol Pathol 26:657-671. PMID:9789953

1997

  • Brooks LR, Jacobson RW, Warren SH, Kohan MJ, Donnelly KC, George S. 1997. Mutagenicity of HPLC-fractionated urinary metabolites from 2,4,6-trinitrotoluene-treated Fisher 344 rats. Environ Mol Mutagen 30:298-302. PMID:9366908
  • Burghardt RC, Barhoumi R. 1997. Analysis of mechanisms of cellular injury on the micrometer scale. Microscopy and Microanalysis 3(2):37-38.
  • Clement BG, Donnelly KC, Ake, Jr., Garcia S, Chen I, Willett KL, Safe SH, Shalat SL. 1997. Chemical and bioassay analysis of water and soil extracts from South Texas. Organohalogen Compounds 32:216-219.
  • Collie SL, Donnelly KC. 1997. Measurement of Mutagenic Activity in Contaminated Soils. In: Protocols in Bioremediation. Humana Press, Totowa, NJ. pp.127-151.
  • Connor K, Ramamoorthy K, Moore M, Mustain M, Chen I, Safe SH, Zacharewski TR, Gillesby B, Joyeux A, Belaguer P. 1997. Hydroxylated polychlorinated biphenyls (PCBs) as estrogens and antiestrogens: structure-activity relationships. Toxicol Appl Pharmacol 145:111-123. PMID:9221830
  • Donnelly KC, Chen JC, Huebner HJ, Brown K, Autenrieth RL, Bonner JS. 1997. Utility of 4 strains of white rot fungi for the detoxification of 2,4,6-trinitrotoluene in liquid culture. Environ Toxicol Chem 16(6):1105-1110.
  • Donnelly KC, Phillips TD, Onufrock AM, Collie SL, Huebner HJ. 1997. Genotoxicity model and complex mixtures of polycyclic aromatic hydrocarbons. In: Environmental Toxicology and Risk Assessment: Biomarkers and Risk Assessment. ASTM Special Tech. Publ. 1071-720X, Vol. 1306, Am. Soc. for Testing and Materials, Philadelphia, PA. pp.138-148.
  • Donnelly KC, Washburn KS, Huebner HJ. 1997. Remediation and risk assessment of contaminated soils. Biotechnology International 1:221-229.
  • Dwyer MR, Kubena LF, Harvey RB, Mayura K, Sarr AB, Buckley SG, Bailey RH, Phillips TD. 1997. Effects of inorganic adsorbents and cyclopiazonic acid in broiler chickens. Poultry Science 76:1141-1149. PMID:9251144
  • Fielden MR, Chen I, Chittim B, Safe SH, Zacharewski TR. 1997. Examination of the estrogenicity of 2,4,6,2',6'-pentachlorobiphenyl (PCB 104), its hydroxylated metabolite 2,4,6,2',6'-pentachloro-4-biphenylol (HO-PCB 104), and a further chlorinated derivative, 2,4,6,2',4',6'-hexachlorobiphenyl (PCB 155). Environ Health Perspect 105(11):1238-1248. PMID:9370515 PMCID:PMC1470342
  • Legare ME, Hanneman WH, Barhoumi R, Tiffany-Castiglioni E. 1997. The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure in primary astroglia: identification of biochemical and cellular targets. Neurotoxicology 18:515-524. PMID:9291499
  • McKenzie KS, Sarr AB, Mayura K, Bailey RH, Miller DR, Rogers TD, Norred WP, Voss KA, Plattner RD, Kubena LF, Phillips TD. 1997. Oxidative degradation and detoxification of mycotoxins using a novel source of ozone. Food Chem Toxicol 35(8):807-820. doi:10.1016/S0278-6915(97)00052-5 PMID:9350226
  • Meola S, Meola R, Barhoumi R, Miles J, Burghardt RC. 1997. Laser cytometric analysis of permethrin toxicity in insect and mammalian cells. Toxic Subst Mech 16:237-250.
  • Moore M, Mustain M, Daniel KD, Chen I, Safe SH, Zacharewski TR, Gillesby B, Joyeux A, Belaguer P. 1997. Antiestrogenic activity of hydroxylated polychlorinated biphenyl congeners identified in human serum. Toxicol Appl Pharmacol 142:160-168. PMID:9007045
  • Moorthy B, Sriram P, Randerath E, Randerath K. 1997. Effects of cytochrome P450 inducers on tamoxifen genotoxicity in female mice in vivo. Biochem Pharmacol 53:663-669. PMID:9113085
  • Onufrock AM, Donnelly KC. 1997. Mutagenic potential of fractions and reconstituted mixtures of polycyclic aromatic hydrocarbons. In: Environmental Toxicology and Risk Assessment: Biomarkers and Risk Assessment. ASTM Special Tech. Publ. 1071-720X, Vol. 1306, Am. Soc. for Testing and Materials, Philadelphia, PA.
  • Ramamoorthy K, Safe SH. 1997. The antiestrogenic activity of 3,3',4,4'-tetrachlorobiphenyl in the immature mouse uterus. Organohalogen Compounds 34:334-337.
  • Ramamoorthy K, Vyhlidal C, Wang F, Chen I, Safe SH, McDonnell DP, Leonard LS, Gaido KW. 1997. Additive estrogenic activities of a binary mixture of 2',4',6'-trichloro- and 2',3',4',5'-tetrachloro-4-biphenylol. Toxicol Appl Pharmacol 147:93-100. PMID:9356311
  • Ramamoorthy K, Wang F, Chen I, Norris JD, McDonnell DP, Gaido KW, Bocchinfuso WP, Korach KS, Safe SH. 1997. Potency of combined estrogenic pesticides. Science 275:405. PMID:9005556
  • Ramamoorthy K, Wang F, Chen I, Norris JD, McDonnell DP, Leonard LS, Gaido KW, Bocchinfuso WP, Korach KS, Safe SH. 1997. Estrogenic activity of a dieldrin/toxaphene mixture in the mouse uterus, MCF-7 human breast cancer cells, and yeast-based estrogen receptor assays: no apparent synergism. Endocrinology 138:1520-1527. PMID:9075711
  • Randerath E, Zhou GD, Randerath K. 1997. Organ-specific oxidative DNA damage associated with normal birth in rats. Carcinogenesis 17:2564-2570. PMID:9006090
  • Randerath K, Zhou GD, Monk SA, Randerath E. 1997. Enhanced levels in neonatal rat liver of 7,8-dihydro-8-oxo-2'-deoxyguanosine (8-hydroxydeoxyguanosine), a major mutagenic oxidative DNA lesion. Carcinogenesis 18:1419-1421. PMID:9230290
  • Randerath K, Zhou GD, Randerath E, Safe SH, Donnelly KC. 1997. Comparative [32P]-postlabeling analysis of exogenous and endogenous DNA adducts in mouse skin exposed to a wood-preserving waste extract, a complex mixture of polycyclic and polychlorinated chemicals. Environ Mol Mutagen 29(4):372-378. PMID:9212788
  • Safe SH. 1997. Limitations of the toxic equivalency factor approach for risk assessment of TCDD and related compounds. Teratog Carcinog Mutagen 17:285-304. PMID:9508738
  • Safe SH, Connor K, Ramamoorthy K, Gaido KW, Maness SC. 1997. Human exposure to endocrine-active chemicals: hazard assessment problems. Regul Toxicol Pharmacol 26:52-58. PMID:9339480
  • Wang W, Porter WW, Burghardt RC, Safe SH. 1997. Mechanism of inhibition of MDA-MB-468 cell growth by 2,3,7,8,-tetrachlorodibenzo-p-dioxin. Carcinogenesis 18:925-933. PMID:9163677
  • Wang W, Smith, III R, Burghardt RC, Safe SH. 1997. 17 beta-Estradiol-mediated growth inhibition of MDA-MB-468 cells stably transfected with the estrogen receptor: cell cycle effects. Mol Cell Endocrinol 133(1):49-62. PMID:9359472
  • Willett KL, Safe SH. 1997. Hydroxylated polychlorinated biphenyls identified in human serum as inducers and inhibitors of EROD activity in the H4IIE cell bioassay. Organohalogen Compounds 34:172-177.
  • Zacharewski TR, Sutter TR, Safe SH, Greenlee WF, Connolly RB. 1997. Concerns with the use of a toxic equivalency factor (TEF) approach for risk assessment of "dioxin-like" compounds. Organohalogen Compounds 34:91-94.
  • Zhao F, Mayura K, Kocurek N, Edwards JF, Kubena LF, Safe SH, Phillips TD. 1997. Inhibition of 3,3',4,4',5-pentachlorobiphenyl-induced chicken embryotoxicity by 2,2',4,4',5,5'-hexachlorobiphenyl. Fundam Appl Toxicol 35:1-8. PMID:9024668
  • Zhao F, Mayura K, Safe SH, Phillips TD, Harper N. 1997. Inhibition of 3,3',4,4',5-Pentachlorobiphenyl induced fetal cleft palate and immunotoxicity in C57BL/6 mice by 2,2',4,4',5,5'-Hexacholorobiphenyl. Chemosphere 34(5-7):1605-1613. doi:10.1016/S0045-6535(97)00456-6 PMID:9134691
  • Zoran DL, Barhoumi R, Burghardt RC, Chapkin RS, Lupton JR. 1997. Diet and carcinogen alter luminal butyrate concentration and intracellular pH in isolated rat colonocytes. Nutr Cancer 27:222-230. PMID:9101550

1996

  • Barbee GC, Brown K, Thomas JC, Donnelly KC, Murray HE. 1996. Mutagenic activity (Ames test) of wood-preserving waste sludge applied to soil. Bull Environ Contam Toxicol 57:54-62. PMID:8661460
  • Barhoumi R, Burghardt RC. 1996. Kinetic analysis of the chronology of patulin- and gossypol-induced cytotoxicity in vitro. Fundam Appl Toxicol 30:290-297. PMID:8812278
  • Barhoumi R, Mouneimne Y, Phillips TD, Safe SH, Burghardt RC. 1996. Alteration of oxytocin-induced calcium oscillations in Clone 9 cells by toxin-exposure. Fundam Appl Toxicol 33:220-228. PMID:8921340
  • Bordelon NR, Washburn KS, He L, Donnelly KC. 1996. Bioavailability of Genotoxic Mixtures in Soil. In: Proceedings of the Hazardous Substance Research Center (HSRC) / Waste-Management Education & Research Consortium Joint Conference on the Environment. pp.560-568.
  • Bowes RC, Parrish AR, Steinberg MA, Willett KL, Zhao W, Savas U, Jefcoate CR, Safe SH, Ramos KS. 1996. Atypical cytochrome P450 profiles in glomerular mesangial cells at the mRNA and enzyme level. Evidence for CYP1A1 and CYP1B1 expression and their involvement in benzo(a)pyrene metabolism. Biochem Pharmacol 52(4):587-595. doi:10.1016/0006-2952(96)00310-3 PMID:8759031
  • Connor K, Ramamoorthy K, Safe SH. 1996. The effects of hydroxylated polychlorinated biphenyls (PCBs) on the immature rat and mouse uterus. Organohalogen Compounds 29:312-315.
  • De Flora S, Izzotti A, Randerath K, Randerath E, Bartsch H, Nair J, Balansky R, Van Schooten F, Degan P, Fronza G, Walsh D, Lewtas J. 1996. DNA adducts and chronic degenerative diseases. Pathogenetic relevance and implications in preventive medicine. Mutat Res 366:197-238. PMID:9033668
  • Donnelly KC, Huebner HJ. 1996. Bioassay-based risk assessment of complex mixtures. In: Superfund Risk Assessment in Soil Contamination Studies. ASTM Special Technical Publication 0066-0558, Vol. 1264. American Society for Testing and Materials, pp.132-148.
  • Donnelly KC, Thomas JC, Brown K. 1996. Mutagenic potential of environmental samples before and after remediation of a solvent contaminated site. Environ Toxicol Chem 14(6):1281-1286.
  • Hanneman WH, Legare ME, Barhoumi R, Burghardt RC, Safe SH, Tiffany-Castiglioni E. 1996. Stimulation of calcium uptake in cultured rat hippocampal neurons by 2,3,7,8-tetrachlorodibenxo-p-dioxin (TCDD). Toxicology 112:19-28. PMID:8792845
  • Markiewicz KV, Howie LE, Safe SH, Donnelly KC. 1996. Mutagenic potential of binary and complex mixtures using different enzyme induction systems. J Toxicol Environ Health A 47:443-451. PMID:8614014
  • Moorthy B, Randerath K. 1996. Pentachlorophenol enhances 9-hydroxybenzo(a)pyrene-induced hepatic DNA adduct formation in vivo and inhibits microsomal epoxide hydrolase and glutathione S-transferase activities in vitro: likely inhibition of epoxide detoxication by pentachlorophenol. Arch Toxicol 70(11):696-703. PMID:8896715
  • Randerath E, Zhou GD, Donnelly KC, Safe SH, Randerath K. 1996. DNA damage induced in mouse tissues by organic wood preserving waste extracts as assayed by 32P-postlabeling. Arch Toxicol 70(11):683-695. PMID:8896714
  • Randerath K, Randerath E, Smith CV, Chang J. 1996. Structural origins of bulky oxidative DNA adducts (Type II I-compounds) as deduced by oxidation of oligonucleotides of known sequence. Chem Res Toxicol 9:247-254. PMID:8924599
  • Washburn KS, Huebner HJ, Safe SH, Phillips TD, Donnelly KC. 1996. Development of an Instrumental Fractionation and Quantitation Scheme for Selected Polynuclear Aromatic Hydrocarbons Present in extracts from Wood-Preserving Waste. In: Proceedings of the Hazardous Substance Research Center (HSRC) / Waste-Management Education & Research Consortium Joint Conference on the Environment. pp.400-407.
  • Weber TJ, Chapkin RS, Davidson LA, Ramos KS. 1996. Modulation of protein kinase C (PKC)-related signal transduction by 2,3,7,8-tetrachlorodibenzo-p-dioxin exhibits cell cycle dependence. Arch Biochem Biophys 328(2):227-232. PMID:8644998

1995

  • Barhoumi R, Bailey RH, Burghardt RC. 1995. Kinetic analysis of glutathione in anchored cells with monochlorobimane. Cytometry Part A 19:226-234. PMID:7736868
  • Barhoumi R, Bailey RH, Hutchinson RW, Bowen JA, Burghardt RC. 1995. Enhancement of melphalan toxicity by octanol in ovarian adenocarcinoma cell lines: effects of altered cell-cell communication, glutathione levels and plasma membrane fluidity. Fundam Appl Toxicol 25:70-79. PMID:7601329
  • Bowes RC, Ramos KS. 1995. Renal mesangial cell proliferation is enhanced by sequential challenge with benzo(a)pyrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin. Organohalogen Compounds 25:253-258.
  • Bowes RC, Weber TJ, Ramos KS. 1995. Induction of highly proliferative phenotypes in cultured glomerular mesangial cells by benzo(a)pyrene alone or in combination with methoxamine. Arch Biochem Biophys 323:243-250. PMID:7487084
  • Brown K. 1995. Decontamination of polluted soil. In: Proceedings of the 2nd Int. Conference on the Biogeochemistry of Trace Elements.
  • Brown K. 1995. Lysimeters. In: Encyclopedia of Soil Science & Technology (2nd ed.).
  • Brown K. 1995. Pore size distribution. In: Encyclopedia of Soil Science & Technology (2nd ed.).
  • Brown K. 1995. Soil solution sampling. In: Encyclopedia of Soil Science & Technology (2nd ed.).
  • Burghardt RC, Barhoumi R, Sewall TC, Bowen JA. 1995. Cyclic AMP-induces rapid increases in gap junction permeability and changes in the cellular distribution of connexin43. Journal of Membrane Biology 148(3):243-253. doi:10.1007/BF00235042 PMID:8747556
  • Chaloupka K, Steinberg MA, Santostefano M, Rodriguez LV, Goldstein L, Safe SH. 1995. Induction of Cyp1a-1 and Cyp1a-2 gene expression by a reconstituted mixture of polynuclear aromatic hydrocarbons in B6C3F1 mice. Chem Biol Interact 96:207-221. PMID:7750161
  • Collie SL, Donnelly KC, Bae B, Autenrieth RL, Bonner JS. 1995. Degradation of 2,4,6-trinitrotoluene in an aerobic bioreactor. Chemosphere 32(4):3025-3032.
  • Connor K, Harper N, Safe SH. 1995. Toxic equivalency factors for mono- and diortho-substituted PCB congeners in B6C3F1 mice. Organohalogen Compounds 25:319-322.
  • Connor K, Safe SH. 1995. Development and validation of toxic equivalency factors (TEFs) for PCBs in female Sprague-Dawley rats. Organohalogen Compounds 25:323-326.
  • Connor K, Safe SH, Jefcoate CR, Larsen M. 1995. Structure-dependent induction of CYP2B by polychlorinated biphenyl congeners in female Sprague-Dawley rats. Biochem Pharmacol 50:1913-1920. PMID:8615872
  • Connor K, Steinberg MA, Safe SH, Harper N. 1995. Immunosuppressive activity of polychlorinated biphenyl mixtures and congeners: non-additive (antagonistic) interactions. Fundam Appl Toxicol 27(1):131-139. doi:10.1006/faat.1995.1116 PMID:7589923
  • Dickerson R, Howie-Keller L, Safe SH. 1995. Alkyl polychlorinated dibenzofurans and related compounds as antiestrogens in the female rat uterus: Structure-Activity Studies. Toxicol Appl Pharmacol 135:287-298. PMID:8545839
  • Donnelly KC, Safe SH, Randerath K. 1995. Bioassay-based risk assessment of complex mixtures. J Hazard Mater 41:341-350.
  • Harper N, Steinberg MA, Thomsen J, Safe SH. 1995. Halogenated aromatic hydrocarbon-induced suppression of the plaque-forming cell response in B6C3F1 splenocytes cultured with allogenic mouse serum: Ah receptor structure activity relationships. Toxicology 99:199-206. PMID:7610466
  • Hong MS, Dale BE, Donnelly KC. 1995. Detoxification of pentachlorophenol using KPEG dehalogenation. Environ Sci Technol 29(3):702-708.
  • Hong MS, Dale BE, Donnelly KC. 1995. Genotoxicity profiles for wood preserving waste after KPEG chemical dehalogenation. Environ Sci Technol 29(3):702.
  • Hong MS, He L, Dale BE, Donnelly KC. 1995. Genotoxicity profiles and reaction characteristics of potassium polyethylene glycol dehalogenation of wood preserving waste. Environ Sci Technol 29(3):702-708. doi:10.1021/es00003a018 PMID:22200279
  • Hutchinson RW, Barhoumi R, Burghardt RC. 1995. Laser cytometric analysis of gossypol-induced cytotoxicity. Toxic Subst Mech 14:169-184.
  • Moorthy B, Liehr JG, Randerath E, Randerath K. 1995. Evidence from [32P]-postlabeling and the use of pentachlorophenol for a novel metabolic activation pathway of diethyl stilbestrol and its dimethylether in mouse liver: likely " alpha-hydroxylation of ethyl group(s) followed by sulfate conjugation. Carcinogenesis 16(11):2643-2648.
  • Moorthy B, Sriram P, Randerath K. 1995. Effects of a single dose of the cytochrome P450 inducer, $-naphthoflavone, on hepatic and renal covalent DNA modifications (I-compounds). Toxicology 104:165-177. PMID:8560495
  • Ou X, Ramos KS. 1995. Regulation of cytochrome P451A1 gene expression in vascular smooth muscle cells through aryl hydrocarbon receptor-mediated signal transduction requires a protein synthesis inhibitor. Arch Biochem Biophys 318:122-130. PMID:7840604
  • Prasad TV, Brown K. 1995. Permachor method to predict diffusivity coefficients of organics in aqueous solutions in flexible membrane liners. Waste Management & Research 13:47-53.
  • Ramos KS, Zhao W. 1995. Inhibition of DNA synthesis in primary cultures of adult rat hepatocytes by benzo(a)pyrene: Role of Ah receptor-dependent events. Toxicology 99(3):179-189. doi:10.1016/0300-483X(94)03028-Z PMID:7610464
  • Randerath E, Watson WP, Zhou GD, Chang J, Randerath K. 1995. Intensification and depletion of specific bulky renal DNA adducts (I-compounds) following exposure of male F344 rats to the renal carcinogen ferric nitrilotriacetate (Fe-NTA). Mutat Res 341:265-279. PMID:7531286
  • Randerath E, Zhou GD, Hart RW, Randerath K. 1995. Age-dependent indigenous covalent DNA modifications (I-compounds). In: Implications for the Design and Interpretation of Toxicity and Carcinogenicity Studies. ILSI Press, Washington, DC. pp.229-244.
  • Randerath K, Chang J, Randerath E. 1995. Age-dependent DNA modifications (I-compounds). In: Effects of Carcinogenesis and Oxidative Stress. Birkhuser Verlag, Basel, Switzerland. pp.77-87.
  • Randerath K, Randerath E, Filburn C. 1995. Genomic and mitochondrial DNA alterations with aging. In: Handbook of the Biology of Aging, 4th Edition. Academic Press, NY.
  • Safe SH. 1995. Human dietary intake of aryl hydrocarbon (Ah) receptor agonists: mass balance estimates of exodioxins and endodioxins and implications for health assessment. Organohalogen Compounds 26:7-13.
  • Safe SH, Rodriguez LV, Goldstein L. 1995. Toxic equivalency factor approach for risk assessment of combustion by-products. Toxicol Sci 49:181-191.
  • Safe SH, Washburn KS, Zacharewski TR, Phillips TD. 1995. Synthesis and characterization of hydroxylated polychlorinated biphenyls (PCBs) identified in human serum. Chemosphere 31(4):3017-3023. doi:10.1016/0045-6535(95)00162-2 PMID:7552046
  • Vulimiri SV, Gupta MS, Smith CV, Moorthy B, Randerath K. 1995. Rapid decreases in indigenous covalent DNA modifications (I-compounds) in male Fischer 344 ra liver DNA by diquat treatment. Chem Biol Interact 95:1-16. PMID:7697743
  • Washburn KS, Phillips TD. 1995. Development of a field-practical assay for water-solvated chlorophenols. J Hazard Mater 41:371-381.
  • Zhao F, Mayura K, Hutchinson RW, Lewis RP, Burghardt RC, Phillips TD. 1995. Developmental toxicity and structure-activity relationships of chlorophenols using human embryonic palatal mesenchymal cells. Toxicol Lett 78(1):35-42. doi:10.1016/0378-4274(95)99684-A PMID:7604397

1983

  • Li X, Zhang S, Safe SH. 1983. [Central effect of thyroliberin (TRH)]. Psychiatr Pol 17(1):77-84. PMID:16413991
Back
to Top