Superfund Research Program
Mechanisms of Arsenic Transport in Kidney and Bladder
Project Leader: Stephen Wright
Grant Number: P42ES004940
Funding Period: 2000 - 2005
Project-Specific Links
- Project Summary
Publications
2005
- Derbyshire ZE, Halfter UM, Heimark RL, Vaillancourt RR. 2005. Angiotensin II stimulated transcription of cyclooxygenase II is regulated by a novel kinase cascade involving Pyk2, MEKK4 and annexin II. Mol Cell Biochem 271(1-2):77-90. PMID:15881658
2003
- Groves CE, Munoz L, Bahn A, Burckhardt G, Wright S. 2003. Interaction of cysteine conjugates with human and rabbit organic anion transporter 1. J Pharmacol Exp Ther 304(2):560-566. PMID:12538807
- Kaewmokul S, Chatsudthipong V, Evans KK, Dantzler WH, Wright S. 2003. Functional mapping of rbOCT1 and rbOCT2 activity in the S2 segment of rabbit proximal tubule. Am J Physiol Renal Physiol 285(6):F1149-1159. PMID:12944320
2002
- Bahn A, Knabe M, Hagos Y, Rodiger M, Godehardt S, Graber-Neufeld DS, Evans KK, Burckhardt G, Wright S. 2002. Interaction of the metal chelator 2,3-dimercapto-1-propanesulfonate with the rabbit multispecific organic anion transporter 1 (rbOAT1). Mol Pharmacol 62(5):1128-1136. PMID:12391276
- Burckhardt BC, Drinkuth B, Menzel C, Konig A, Steffgen J, Wright S, Burckhardt G. 2002. The renal Na+-dependent dicarboxylate transporter, NaDC-3, translocates dimethyl- and disulfhydryl-compounds and contributes to renal heavy metal detoxification. J Am Soc Nephrol 13(11):2628-2638. PMID:12397032
- Liu Z, Shen J, Carbrey JM, Mukhopadhyay R, Agre P, Rosen BP. 2002. Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9. Proc Natl Acad Sci U S A 99(9):6053-6058. PMID:11972053
- Wright S, Earp J, Evans KK. 2002. Unstirred layers: a complicating factor in comparison of kinetics of cloned transporters with activity of renal proximal tubules. J Am Soc Nephrol
- Zhang X, Evans KK, Wright S. 2002. Molecular cloning of rabbit organic cation transporter rbOCT2 and functional comparisons with rbOCT1. Am J Physiol Renal Physiol 283:124-133. PMID:12060594
2001
- Bahn A, Graber-Neufeld DS, Godehardt S, Hillemann A, Burckhardt G, Wright S. 2001. Role of the organic anion transporter 1 (OAT1) in renal heavy metal detoxification. FASEB J 15:A434.
- Burckhardt BC, Drinkuth B, Steffgen J, Wright S, Burckhardt G. 2001. Role of the high affinity sodium-dependent dicarboxylate transporter from winter flounder (NADC-3) in renal deroxification. J Am Soc Nephrol 12:47A.
- Islinger F, Gekle M, Wright S. 2001. Interaction of 2,3-dimercapto-1-propane sulfonate with the human organic anion transporter hOAT1. J Pharmacol Exp Ther 299(2):741-747. PMID:11602689
- Islinger F, Wright S. 2001. Handling of the mercury-chelator DMPS (2,3-dimercapto-1-propane-sulfonic acid) by the human organic anion transporter (hOAT1). FASEB J 15:A853.
1999
- Porter AC, Fanger GR, Vaillancourt RR. 1999. Signal transduction pathways regulated by arsenate and arsenite. Oncogene 18(54):7794-7802. PMID:10618720