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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Project Publications: University of North Carolina-Chapel Hill: Biomarkers of Human Susceptibility to Vinyl Chloride

Superfund Research Program

Biomarkers of Human Susceptibility to Vinyl Chloride

Project Leaders: David G. Kaufman, Howard L. Liber (Massachusetts General Hospital)
Grant Number: P42ES005948
Funding Period: 1995 - 2000

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Publications

1998

  • Cistulli CA, Kaufmann WK. 1998. P53-dependent signaling sustains DNA replication and enhances clonogenic survival in 254 nm ultraviolet-irradiated human fibroblasts. Cancer Res 58:1993-2002. PMID:9581844
  • Li Y, Asherova M, Brandt-Rauf PW. 1998. Mutant oncoprotein biomarkers in chemical carcinogenesis. In: Biomarkers: Medical and Workplace Applications. Joseph Henry Press, Washington, DC. pp.345-353.
  • Marion M. 1998. Critical genes as early warning signs: example of vinyl chloride. Toxicol Lett 102/103:603-607. PMID:10022320
  • Smith SJ, Li Y, Whitley R, Marion M, Partilo S, Carney WP, Brandt-Rauf PW. 1998. Molecular epidemiology of p53 mutations in workers exposed to vinyl chloride. Am J Epidemiol 147(3):302-308. PMID:9482505

1997

  • Kaufmann WK, Byrd LL, Palmieri D, Nims RW, Rice JM. 1997. TGF-± sustains clonal expansion by promoter-dependent, chemically initiated rat hepatocytes. Carcinogenesis 18(18):1381-1387. PMID:9230284

1995

  • Chiang S, Craft TR, Skopek TR, Swenberg JA. 1995. Mutation spectra of vinyl chloride (VC) and chloroethylene oxide (CEO) at the hprt gene in metabolically-competent human lymphoblastoid lines. International Toxicologist 7(1):46P9.
  • Chiang S, Skopek TR, Swenberg JA. 1995. Mutagenicity of vinyl chloride and its metabolites, and vinyl fluoride in a metabolically competent human lymphoblastoid line. Environ Health Perspect 15(1):79.
  • Chiao C, Zhang Y, Kaufman DG, Kaufmann WK. 1995. Derivation of phenobarbital-responsive immortal rat hepatocytes. Am J Pathol 146(5):1248-1259. PMID:7747817
  • Chiao C, Zhang Y, Kaufman DG, Kaufmann WK. 1995. Phenobarbital modulates the type of cell death by initiated hepatocytes during deprivation of serum in vitro. Hepatology 22(1):297-303. PMID:7601424
  • Zhang Y, Chiao C, Byrd LL, Kaufman DG, Kaufmann WK. 1995. Liver tumor promotion and the suppression of p53-dependent cell cycle checkpoint function. In: Liver Regeneration and Carcinogenesis: molecular and cellular mechanisms. Academic Press,
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