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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Project Publications: University of North Carolina-Chapel Hill: Comparative Toxicogenomics and Individual Differences in the Human Response to Dermal Exposure to Polycyclic Aromatic Hydrocarbons

Superfund Research Program

Comparative Toxicogenomics and Individual Differences in the Human Response to Dermal Exposure to Polycyclic Aromatic Hydrocarbons

Project Leader: Leena A. Nylander-French
Grant Number: P42ES005948
Funding Period: 2000 - 2011

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Publications

2010

2009

  • Kim D, Nylander-French LA. 2009. Physiologically-Based Toxicokinetic Models and Their Application in Human Exposure and Internal Dose Assessment. In: Molecular, Clinical and Environmental Toxicology Volume 1. pp.470.

2008

  • Chao YE, Zhao Y, Kupper LL, Nylander-French LA. 2008. Quantifying the relative importance of predictors in multiple linear regression analyses for public health studies. J Occup Environ Hyg 5(8):519-529. doi:10.1080/15459620802225481 PMID:18569519
  • Kang-Sickel JC, Nam T, Jayaraj K, Ball LM, French JE, Klapper DG, Gold A, Nylander-French LA. 2008. S-arylcysteine-keratin adducts as biomarkers of human dermal exposure to aromatic hydrocarbons. Chem Res Toxicol 21(4):852-858. doi:10.1021/tx7003773 PMID:18361511
  • Kim D, Farthing MW, Miller CT, Nylander-French LA. 2008. Mathematical description of the uptake of hydrocarbons in jet fuel into the stratum corneum of human volunteers. Toxicol Lett 178(3):146-151. doi:10.1016/j.toxlet.2008.03.005 PMID:18423910 PMCID:PMC2443700

2007

  • Kim D, Andersen ME, Chao YE, Egeghy PP, Rappaport SM, Nylander-French LA. 2007. PBTK modeling demonstrates contribution of dermal and inhalation exposure components to end-exhaled breath concentrations of naphthalene. Environ Health Perspect 115(6):894-901. doi:10.1289/ehp.9778 PMID:17589597 PMCID:PMC1892111
  • Kim D, Andersen ME, Chao YE, Egeghy PP, Rappaport SM, Nylander-French LA. 2007. Prediction of human dermal and inhalation exposures to jet fuel by analysis of a PBTK model. Environ Health Perspect 115(6):894-901.

2006

  • Chao YE, Kupper LL, Serdar B, Egeghy PP, Rappaport SM, Nylander-French LA. 2006. Dermal exposure to jet fuel JP-8 significantly contributes to the production of urinary naphthols in fuel-cell maintenance workers. Environ Health Perspect 114(2):182-185. PMID:16451852 PMCID:PMC1367829
  • Kim D, Andersen ME, Nylander-French LA. 2006. A dermatotoxicokinetic model of human exposures to jet fuel. Toxicol Sci 93(1):22-33. doi:10.1093/toxsci/kfl048 PMID:16801332
  • Kim D, Andersen ME, Nylander-French LA. 2006. Dermal absorption and penetration of jet fuel components in humans. Toxicol Lett 165(1):11-21. doi:10.1016/j.toxlet.2006.01.009 PMID:16497449

2005

  • Chao YE, Gibson RL, Nylander-French LA. 2005. Dermal exposure to jet fuel (JP-8) in US Air Force personnel. Ann Occup Hyg 49(7):639-645. PMID:16006502

2004

  • Chao YE, Nylander-French LA. 2004. Determination of keratin protein in a tape-stripped skin sample from jet fuel exposed skin. Ann Occup Hyg 48(1):65-73. PMID:14718347
  • Mattorano DA, Kupper LL, Nylander-French LA. 2004. Estimating dermal exposure to jet fuel (naphthalene) using adhesive tape strip samples. Ann Occup Hyg 48(2):139-146. PMID:14990435

2003

  • Gold A, Nam T, Jayaraj K, Sangaiah R, Klapper DG, Ball LM, French JE, Nylander-French LA. 2003. Synthesis of S-aryl-D,L-cysteines and incorporation into keratin sequences. Organic Preparations and Procedures International 35(4):375-382.

2002

  • Nam T, Sangaiah R, Gold A, Lacks GD, Nylander-French LA, French JE. 2002. Synthesis of FMOC-protected S-arylcysteines and modified keratin sequence peptides as specific epitopes as immunogens. Polycyclic Aromatic Compounds 22(3-4):239-248.

2001

  • Nam T, Sangaiah R, Gold A, Lacks GD, Nylander-French LA, French JE. 2001. Synthesis of FMOC-protected S-aryclysteines and modified keratin sequence peptides as specific epitopes as immunogens. In: Proceedings of the 18th International Symposiium on Polycyclic Aromatic Compounds, Sept 9-13. Cincinnati, OH.
  • Nylander-French LA, Lacks GD, Mattorano DA. 2001. Quantification of naphthalene dermal exposure using non-invasive tape stripping of the stratum corneum, extraction, and normalization against keratin. Arbete och Halsa 10:23-24.

2000

  • Nylander-French LA. 2000. A tape-stripping method for measuring dermal exposure to multifunctional acrylates. Ann Occup Hyg 44:645-651. PMID:11108786
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