Superfund Research Program

Stage-specific Actions of Cadmium During Spermatogenesis

Project Leader: Gloria V. Callard
Grant Number: P42ES007381
Funding Period: 1995 - 2000

Project-Specific Links

Publications

2003

• Carnell AN, Goodman JI, Abriola LM. 2003. The long (LINEs) and the short (SINEs) of it: altered methylation as a precursor to toxicity. Toxicol Sci 65:229-235. PMID:12773759
• Chen Y, Su HJ, Guo YL, Hsueh Y, Ryan LM, Lee M, Christiani DC. 2003. Arsenic methylation and bladder cancer risk in Taiwan. Cancer Causes Control 14(4):303-310. PMID:12846360
• Collier JM, Selmin O, Johnson PD, Runyan RB. 2003. Trichloroethylene effects on gene expression during cardiac development. Birth Defects Res A Clin Mol Teratol 67(7):488-495. doi:10.1002/bdra.10073 PMID:14565619
• Henderson PT, Delaney JC, Muller JG, Neeley WL, Tannenbaum SR, Burrows CJ, Essigmann JM. 2003. The hydantoin lesions formed from oxidation of 7,8-dihydro-8-oxoguanine are potent sources of replication errors in vivo. Biochemistry 42(31):9257-9262. doi:10.1021/bi0347252 PMID:12899611
• Monk SA, Denison MS, Rice RH. 2003. Reversible stepwise negative regulation of CYP1A1 in cultured rat epidermal cells. Arch Biochem Biophys 419(12):158-169. PMID:14592459
• Zhang Q, Salnikow K, Kluz T, Chen L, Su W, Costa M. 2003. Inhibition and reversal of nickel-induced transformation by the histone deacetylase inhibitor trichostatin A. Toxicol Appl Pharmacol 192(3):201-211. PMID:14575637
• Zhou HZ, Randes-Pehrson G, Geard CR, Brenner DJ, Hall EJ, Hei TK, Ahmed KM. 2003. Interaction between radiation-induced adaptive response and bystander mutagenesis in mammalian cells. Radiation Research 160(5):512-516. PMID:14565832 PMCID:PMC4041543

2002

• Nicholls J, Lasley BL, Nakajima ST, Setchell KD, Schneeman BO. 2002. Effect of soy consumption on gonadotropin secretion and acute pituitary response to GnRH in women. J Nutr 132:708-714. PMID:11925465

2001

• Shideler SE, Gee NA, Laughlin LS, Lasley BL. 2001. Estrogen and progesterone metabolites and follicle-stimulating hormone in the aged macaque female. Biol Reprod 65(6a0:1718-1725. PMID:11717133

2000

• Betka M, Welenc A, Franks DG, Hahn ME, Callard GV. 2000. Characterization of two aryl hydrocarbon receptor (AHR) mRNA forms in Squalus acanthias and stage-dependent expression during spermatogenesis. Bull Mt Desert Isl Biol Lab Salisb Cove Maine 39:65-67.
• Callard GV, Wang C. 2000. PCR-Differential display identifies a subset of stage-dependent and cadmium-regulated mitochondrial genes during spermatogenesis. In: Proceedings of the International Symposium on Hormones & Endocrine Disruptors in Food and Water: Possible Effects on Human Health. Copenhagen, Denmark.
• Novak CM, Nunez AA. 2000. A sparse projection from the suprachiasmatic nucleus to the sleep active ventrolateral preoptic area in the rat. Neuroreport 11(1):93-96. PMID:10683837
• Novak CM, Smale L, Nunez AA. 2000. Rhythms in Fos expression in brain areas related to the sleep-wake cycle in the diurnal Arvicanthis niloticus. Am J Physiol Regul Integr Comp Physiol 278(5):R1267-R1274. PMID:10801296

1999

• Betka M, Callard GV. 1999. Stage-dependent accumulation of cadmium and induction of metallothionein-like binding activity in the testis of the dogfish shark Squalus acanthias. Biol Reprod 60(1):14-22. PMID:9858481
• Betka M, Welenc A, Hahn ME, Callard GV. 1999. Stage-related distribution of two arylhydrocarbon receptor (AhR) mRNA variants and differential effects of Ah ligands on cell proliferation and death during spermatogenesis in the spiny dogfish shark (Squalus acanthias). In: Proceedings of the 1999 SETAC (Society of Environmental Toxcology and Chemistry) Annual Meeting.
• Callard GV, Callard IP. 1999. Spermatogenesis in subavian vertebrates. In: Encyclopedia of Reproduction, Vol 4. Academic Press, pp.563-570.
• Callard GV, McClusky LM, Betka M. 1999. Stage-specific effects of hormones and spermatotoxicants on germ cell proliferation and death: the shark testis model. In: Proceedings of the Symposium on Endocrine Disruptors. 5th International Congress Physiology Biochemistry Calgary. Calgary, Canada.
• Callard GV, Wang C, Sikora R, Betka M. 1999. In vivo effects of cadmium on the estrogen signaling pathway during spermatogenesis. In: Proceedings of the Symposium on Estrogens in the Environment. New Orleans, LA.
• Kleinow KM, Doi AM, Smith AA. 1999. Distribution of C219 detectable P-glycoprotein transporter in the catfish. In: Proceedings of the PRIMO Meeting.
• Ma W, Kamdem P, Loconto PR, Pan Y, Gage DM, Dawson-Andoh BE. 1999. Characterization and bioremediation of birch condensate. Wood and Fiber Science 31(4):370-375.
• Nunez AA, Bult A, McElhinny TL, Smale L. 1999. Daily rhythms of Fos expression in hypothalamic targets of the suprachiasmatic nucleus in diurnal and nocturnal rodents. J Biol Rhythms 14(4):300-306. PMID:10447310

1998

• Betka M, Callard GV. 1998. Cloning of an androgen receptor cDNA from Squalus acanthias testis. Bull Mt Desert Isl Biol Lab Salisb Cove Maine 37:111.
• Betka M, Callard GV. 1998. Negative feedback control of the spermatogenic progression by testicular estrogen synthesis: insights from the shark testis model. APMIS 106(1-6):252-258. doi:10.1111/j.1699-0463.1998.tb01344.x PMID:9524587
• Callard GV, McClusky LM, Betka M. 1998. Apoptosis as a normal mechanism of growth control and target of toxicant actions during spermatogenesis: insights using the shark testis model. In: New Developments in Marine Biotechnology. Kluwer Academic Publishers, pp.125-128.
• McClusky LM. 1998. In vitro analysis of cadmium actions during spermatogenesis. In: Proceedings of the Superfund Basic Research Program (SBRP) Conference, 1998. Boston, MA.
• McClusky LM, Betka M, Callard GV. 1998. Stage-specific actions of cadmium on apoptosis during spermatogenesis. In: Proceedings of the Superfund Basic Research Program (SBRP) Conference, 1998. Boston, MA.

1997

• Betka M. 1997. Cadmium accumulation in cardiac and skeletal muscle of Squalus acanthias. Bull Mt Desert Isl Biol Lab Salisb Cove Maine 36:89.
• Callard GV. 1997. Unconventional models for toxicology research. In: Comprehensive Toxicology, Vol. 10, Reproductive and Endocrine Toxicology. Section I. Male Reproductive Toxicology. Elsevier, NY. pp.235-247.
• Guiney PD, Smolowitz RM, Peterson RE, Stegeman JJ. 1997. Correlation of 2,3,7,8-tetrachlorodibenzo-p-dioxin induction of cytochrome P450 1A in vascular endothelium with toxicity in early life stages of lake trout. Toxicol Appl Pharmacol 143(2):256-273. PMID:9144443
• McClusky LM, Betka M, Callard GV. 1997. Preferential accumulation of cadmium and effects on apoptosis during premiotic stages of spermatogenesis. In: Proceedings of the XIVth Testis Workshop: Germ cell development, division, disruption and death. Serono Symposium. Baltimore, MD.
• McClusky LM, Callard GV. 1997. In situ end-labeling of fragmented DNA in apoptotic germ cells in the spiny dogfish (Squalus acanthias) testis. Bull Mt Desert Isl Biol Lab Salisb Cove Maine 36:106-107.

1996

• Betka M. 1996. Metallothionein induction during spermatogenesis. Bull Mt Desert Isl Biol Lab Salisb Cove Maine 35:93.
• Callard GV. 1996. Endocrinology of Leydig cells in nonmammalian vertebrates. In: The Leydig Cell. Cache River Press, Clearwater, FL. pp.307-332.
• Gillett JW, Ram RN. 1996. Mobilization of Sediment Contamination from the Lake Erie-Lake Ontario-St. Lawrence River basin: The Critical Role of the Food Webs. In: Proceedings of the International Symposium on the St. Lawrence Ecosystem. Cornwall, Ontario, Canada. pp.735.
• McClusky LM, Betka M, Miller D, Callard GV. 1996. Analysis of the apoptotic form of programmed cell death (PCD) during spermatogenesis in spiny dogfish (Squalus acanthias). Bull Mt Desert Isl Biol Lab Salisb Cove Maine 35:96-97.

1995

• Roberts MA, Durst RA. 1995. Detection of polychlorinated biphenyls by liposome-based immunomigration assays. In: Proceedings of the Pacific Basin Conference on Hazardous Waste, Edmonton, Alberta, Canada, 7-12 May, 1995. Edmonton, Alberta, Canada.
• Roberts MA, Durst RA. 1995. Investigation of liposome-based immunomigration sensors for the detection of polychlorinated biphenyls. Anal Chem 67:482-491. PMID:7892998
• Siebert ST, Reeves SG, Roberts MA, Durst RA. 1995. Improved liposome immunomigration strip assay for alachlor determination. Anal Chim Acta 311(3):309-318.

1994

• Neilson JW, Josephson KL, Pepper IL, Arnold RG, DiGiovanni GD, Sinclair NA. 1994. Frequency of horizontal gene transfer of a large catabolic plasmid (pJP4) in soil. Appl Environ Microbiol 60:4053-4058. PMID:7993092

1993

• Dawson BV, Johnson PD, Goldberg SJ, Ulreich JB. 1993. Cardiac teratogenesis of halogenated hydrocarbon-contaminated drinking water. J Am Coll Cardiol 21:1466-1472. PMID:8473657
• Lowe TP, Chen Q, Fernando Q, Keith RL, Gandolfi A. 1993. Elemental analysis of renal slices by proton-induced X-ray emission. Environ Health Perspect 101:302. PMID:8275986

1992

• Neilson JW, Josephson KL, Pillai SD, Pepper IL. 1992. Polymerase chain reaction and gene probe detection of the 2,4-dichlorophenoxyacetic acid degradation plasmid pJP4. Appl Environ Microbiol 58:1271-1275. PMID:1599246

1991

• Grosser RJ, Warshawsky D, Vestal JR. 1991. Indigenous and enhanced mineralization of pyrene, benzo(a)-pyrene and carbazole in soils. Appl Environ Microbiol 57:3462-3469. PMID:1785924