Superfund Research Program
Molecular Mechanisms of Co-Carcinogenic Effect of Arsenite with UV Radiation (ARRA Funded)
Project Leader: Chuanshu Huang
Grant Number: P42ES010344
Funding Period: 2009-2011
Project-Specific Links
- Project Summary
Publications
2013
- Yu Y, Li J, Wan Y, Lu J, Gao J, Huang C. 2013. GADD45 alpha induction by nickel negatively regulates JNKs/p38 activation via promoting PP2C alpha expression. PLoS One 8(3):e57185. doi:10.1371/journal.pone.0057185 PMID:23536762 PMCID:PMC3594291
2012
- Zhang D, Li J, Zhang M, Gao G, Zuo Z, Yu Y, Zhu L, Gao J, Huang C. 2012. The requirement of c-Jun N-terminal kinase 2 in regulation of hypoxia-inducing factor-1 alpha mRNA stability. J Biol Chem 287:34361-34371. doi:10.1074/jbc.M112.365882 PMID:22910906 PMCID:PMC3464542
2011
- Cai T, Li X, Ding J, Luo W, Li J, Huang C. 2011. A cross-talk between NFAT and NF-κB pathways is crucial for nickel-induced COX-2 expression in Beas-2B cells. Curr Cancer Drug Targets 11(5):548-559. PMID:21486220 PMCID:PMC3759234 (Completed with ARRA Funds)
- Liu J, Zhang D, Luo W, Yu Y, Li J, Zhang X, Zhang B, Chen J, Wu X, Rosas-Acosta G, Huang C. 2011. X-linked inhibitor of apoptosis protein (XIAP) mediates cancer cell motility via Rho GDP dissociation inhibitor (RhoGDI)-dependent regulation of the cytoskeleton. J Biol Chem 286:15630-15640. doi:10.1074/jbc.M110.176982 PMID:21402697 PMCID:PMC3091172 (Completed with ARRA Funds)
- Song L, Gao M, Dong W, Hu M, Li J, Shi X, Hao Y, Li Y, Huang C. 2011. p85α mediates p53 K370 acetylation by p300 and regulates its promoter-specific transactivity in the cellular UVB response. Oncogene 30(11):1360-1371. doi:10.1038/onc.2010.506 PMID:21057544 PMCID:PMC3761396 (Completed with ARRA Funds)
2010
- Song L, Dong W, Gao M, Li J, Hu M, Guo N, Huang C. 2010. A novel role of IKKalpha in the mediation of UVB-induced G0/G1 cell cycle arrest response by suppressing Cyclin D1 expression. Biochim Biophys Acta 1803(2):323-332. doi:10.1016/j.bbamcr.2010.01.006 PMID:20080131 PMCID:PMC2850076 (Completed with ARRA Funds)
2009
- Ding J, Ning B, Huang Y, Dongyun L, Li J, Chen C, Huang C. 2009. PI3K/Akt/JNK/c-Jun signaling pathway is a mediator for arsenite- induced cyclin D1 expression and cell growth in human bronchial epithelial cells. Curr Cancer Drug Targets 9(4):500-509. doi:10.2174/156800909788486740 PMID:19519318 PMCID:PMC3758122 (Completed with ARRA Funds)
- Yang Z, Song L, Huang C. 2009. Gadd45 proteins as critical signal transducers linking NF-kappaB to MAPK cascades. Curr Cancer Drug Targets 9(8):915-930. doi:10.2174/156800909790192383 PMID:20025601 PMCID:PMC3762688 (Completed with ARRA Funds)