Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Your Environment. Your Health.

Project Publications: Brown University: Biological Dosimetry of Hexavalent Chromium

Superfund Research Program

Biological Dosimetry of Hexavalent Chromium

Project Leader: Anatoly Zhitkovich
Grant Number: P42ES013660
Funding Period: 2005-2014

Learn More About the Grantee

Visit the grantee's eNewsletter page Visit the grantee's eNewsletter page Visit the grantee's Twitter page Visit the grantee's Facebook page Visit the grantee's Video page

Publications

2013

2012

2011

  • Pietruska JR, Liu X, Smith A, McNeil K, Weston P, Zhitkovich A, Hurt RH, Kane AB. 2011. Bioavailability, intracellular mobilization of nickel, and HIF-1α activation in human lung epithelial cells exposed to metallic nickel and nickel oxide nanoparticles. Toxicol Sci 124(1):138-148. doi:10.1093/toxsci/kfr206 PMID:21828359 PMCID:PMC3196652 (Completed with ARRA Funds)

2010

2009

  • Zecevic A, Menard H, Gurel V, Hagan E, DeCaro R, Zhitkovich A. 2009. WRN helicase promotes repair of DNA double-strand breaks caused by aberrant mismatch repair of chromium-DNA adducts. Cell Cycle 8(17):2769-78. PMID:19652551

2008

2007

  • Liu X, Gurel V, Morris D, Murray DW, Zhitkovich A, Kane AB, Hurt RH. 2007. Bioavailability of nickel in single-wall carbon nanotubes. Advanced Materials 19:2790-96.
  • Reynolds M, Stoddard L, Bespalov I, Zhitkovich A. 2007. Ascorbate acts as a highly potent inducer of chromate mutagenesis and clastogenesis: linkage to DNA breaks in G2 phase by mismatch repair. Nucleic Acids Res 35(2):465-476. doi:10.1093/nar/gkl1069 PMID:17169990 PMCID:PMC1802609
  • Reynolds M, Zhitkovich A. 2007. Cellular vitamin C increases chromate toxicity via a death program requiring mismatch repair but not p53. Carcinogenesis 28(7):1613-1620. PMID:17301063

2006

  • Quievryn G, Messer J, Zhitkovich A. 2006. Lower mutagenicity but higher stability of Cr-DNA adducts formed during gradual chromate activation with ascorbate. Carcinogenesis 27(11):2316-2321. PMID:16714765
Back
to Top