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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Project Publications: Harvard School of Public Health: Genetic Mechanisms of Metal Neurotoxicity

Superfund Research Program

Genetic Mechanisms of Metal Neurotoxicity

Project Leader: Quan Lu
Co-Investigator: Tomas R. Guilarte (Columbia University)
Grant Number: P42ES016454
Funding Period: 2010-2015
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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Publications

2017

  • Wagner PJ, Park H, Wang Z, Kirchner R, Wei Y, Su L, Stanfield K, Guilarte TR, Wright RO, Christiani DC, Lu Q. 2017. In vitro effects of lead on gene expression in neural stem cells and associations between up-regulated genes and cognitive scores in children. Environ Health Perspect 125(4):721-729. doi:10.1289/ehp265 PMID:27562236

2012

  • Jiang XF, Pan H, Nabhan JF, Krishnan R, Koziol-White C, Panettieri RA, Lu Q. 2012. A novel EST-derived RNAi screen reveals a critical role for farnesyl diphosphate synthase in beta 2-adrenergic receptor internalization and down-regulation. FASEB J 26:1995-2007. doi:10.1096/fj.11-193870 PMID:22278941 PMCID:PMC3336790
  • Nabhan JF, Hu R, Oh RS, Cohen SN, Lu Q. 2012. Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein. Proc Natl Acad Sci U S A 109(11):4146-4151. doi:10.1073/pnas.1200448109 PMID:22315426 PMCID:PMC3306724
  • Oh RS, Pan W, Yalcin A, Zhang H, Guilarte TR, Hotamisligil GS, Christiani DC, Lu Q. 2012. Functional RNA interference (RNAi) screen identifies system A neutral amino acid transporter 2 (SNAT2) as a mediator of arsenic-induced endoplasmic reticulum stress. J Biol Chem 287(8):6025-6034. doi:10.1074/jbc.M111.311217 PMID:22215663 PMCID:PMC3285369
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