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Program Publications: University of Louisville: Environmental Exposure and Cardiometabolic Disease

Superfund Research Program

Environmental Exposure and Cardiometabolic Disease

Center Director: Sanjay Srivastava
Grant Number: P42ES023716
Funding Period: 2017-2027
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  • Dong J, Browning MH, Reuben A, McAnirlin O, Yuan S, Stephens C, Maisonet M, Zhang K, Hart JE, James P, Yeager R. 2024. The paradox of high greenness and poor health in rural Central Appalachia. Environ Res 248:doi:10.1016/j.envres.2024.118400
  • Hart J, Shuck B, Owen J, Walker KL, Keith RJ. 2024. Biological sex as a moderator of work determinants of health: Implications for work and stress. Healthcare 12(2):doi:10.3390/healthcare12020135 PMID:38255024
  • Hopkins CD, Wessel C, Chen O, El-Kersh K, Cathey D, Cave MC, Cai L, Huang J. 2024. A hypothesis: Potential contributions of metals to the pathogenesis of pulmonary artery hypertension. Life Sciences 336:doi:10.1016/j.lfs.2023.122289 PMID:38007143 PMCID:10872724
  • Xie Z, Sutaria S, Chen JY, Gao H, Conklin DJ, Keith RJ, Srivastava S, Lorkiewicz P, Bhatnagar A. 2024. Evaluation of urinary limonene metabolites as biomarkers of exposure to greenness. Environ Res 245:doi:10.1016/j.envres.2023.117991


  • Adhihetty P, Halder S, Jasinski J, Fu X, Nantz MH. 2023. Harnessing the cation-pi interactions of metallated gold monolayer-protected clusters to detect aromatic volatile organic compounds. Talanta 253:123915. doi:10.1016/j.talanta.2022.123915 PMID:36155323
  • Agbonlahor O, DeJarnett N, Hart J, Bhatnagar A, McLeish AC, Walker KL. 2023. Racial/ethnic discrimination and cardiometabolic diseases: A systematic review. J Racial Ethn Health Disparities 1-25. doi:10.1007/s40615-023-01561-1 PMID:36976513 PMCID:PMC1004413
  • Anderson L, Kanneganti D, Houk MB, Holm RH, Smith T. 2023. Generative AI as a tool for environmental health research translation. Geohealth 7:doi:10.1029/2023GH000875 PMID:37502196 PMCID:PMC10369501
  • Basner M, Smith MG, Jones CW, Ecker AJ, Howard K, Schneller V, Cordoza M, Kaizi-Lutu M, Park-Chavar S, Stahn AC, Dinges DF, Shou H, Mitchell JA, Bhatnagar A, Smith T, Smith AE, Stopforth CK, Yeager R, Keith RJ. 2023. Associations of bedroom PM2.5, CO2, temperature, humidity, and noise with sleep: an observational actigraphy study. Sleep Health 9(3):253-263. doi:10.1016/j.sleh.2023.02.010 PMID:37076419 PMCID:PMC10293115
  • Bolatimi OE, Head KZ, Luo J, Gripshover T, Lin Q, Adiele NV, Watson WH, Wilkerson C, Cai L, Cave MC, Young JL. 2023. Can zinc supplementation attenuate high fat diet-induced non-alcoholic fatty liver disease?. Int J Mol Sci 24(2):1763. doi:10.3390/ijms24021763 PMID:36675277 PMCID:PMC9864360
  • Ge Y, Bruno M, Nash MS, Coates NH, Chorley BN, Cave MC, Beier JI. 2023. Vinyl chloride enhances high-fat diet-induced proteome alterations in the mouse pancreas related to metabolic dysfunction. Toxicol Sci 193(1):103-114. doi:10.1093/toxsci/kfad024 PMID:36892438 PMCID:PMC10176240
  • Groswald AM, Gripshover T, Watson WH, Wahlang B, Luo J, Jophlin LL, Cave MC. 2023. Investigating the acute metabolic effects of the N-methyl carbamate insecticide, methomyl, on mouse liver. Metabolites 13(8):901. doi:10.3390/metabo13080901 PMID:37623845 PMCID:PMC10456691
  • Habil MR, Hein DW. 2023. Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity. Arch Toxicol doi:10.1007/s00204-023-03497-1 PMID:37097310 PMCID:PMC10192036
  • Habil MR, Salazar-Gonzalez R, Doll MA, Hein DW. 2023. Effect of N-acetyltransferase 2 genetic polymorphism on 4,4'-methylenebis(2-chloroaniline)-induced genotoxicity and oxidative stress. Arch Toxicol 97(6):1773-1781. doi:10.1007/s00204-023-03508-1 PMID:37142755 PMCID:PMC10259506
  • Head KZ, Bolatimi OE, Gripshover T, Tan M, Li Y, Audam TN, Jones SP, Klinge CM, Cave MC, Wahlang B. 2023. Investigating the effects of long-term Aroclor 1260 exposure on fatty liver disease in a diet-induced obesity mouse model. Front Gastroenterol 2:1180712. doi:10.3389/fgstr.2023.1180712 PMID:37426695 PMCID:PMC10327714
  • Hein DW, Salazar-Gonzalez R, Doll MA, Zang Y. 2023. The effect of the rs1799931 G857A (G286E) polymorphism on N-acetyltransferase 2-mediated carcinogen metabolism and genotoxicity differs with heterocyclic amine exposure. Arch Toxicol 97(10):2697-2705. doi:10.1007/s00204-023-03577-2 PMID:37592049
  • Hong KU, Hein DW. 2023. N-acetyltransferase 2 haplotype modifies risks for both dyslipidemia and urinary bladder cancer. Pharmacogenet Genomics doi:10.1097/FPC.0000000000000500 PMID:37306342
  • Hopkins CD, Wessel C, Chen O, El-Kersh K, Cave MC, Cai L, Huang J. 2023. Potential roles of metals in the pathogenesis of pulmonary and systemic hypertension. Int J Biol Sci 19(16):5036-5054. doi:10.7150/ijbs.85590 PMID:37928257 PMCID:PMC10620830
  • Liu S, He L, Bannister OB, Li J, Schnegelberger RD, Vanderpuye C, Althouse AD, Schopfer FJ, Wahlang B, Cave MC, Monga SP, Zhang X, Arteel GE, Beier JI. 2023. Western diet unmasks transient low-level vinyl chloride-induced tumorigenesis; potential role of the (epi-)transcriptome. Toxicol Appl Pharmacol 468:116514. doi:10.1016/j.taap.2023.116514 PMID:37061008 PMCID:PMC1016411
  • Luo J, Watson WH, Gripshover T, Qaissi Z, Wahlang B. 2023. Sex-specific effects of acute chlordane exposure in the context of steatotic liver disease, energy metabolism and endocrine disruption. Food Chem Toxicol 180:114024. doi:10.1016/j.fct.2023.114024 PMID:37666290
  • Mattingly DT, Agbonlahor O, Rai J, Hart J, McLeish AC, Walker KL. 2023. Harm perceptions of secondhand e-cigarette aerosol among youth in the United States. Addict Behav 137:107535. doi:10.1016/j.addbeh.2022.107535 PMID:36351320 PMCID:PMC10106102
  • McGraw KE, Konkle S, Riggs DW, Rai SN, DeJarnett N, Xie Z, Keith RJ, Oshunbade A, Hall ME, Shimbo D, Bhatnagar A. 2023. Exposure to volatile organic compounds is associated with hypertension in Black adults: The Jackson Heart Study. Environ Res 223:115384. doi:10.1016/j.envres.2023.115384 PMID:36796615 PMCID:PMC10134439
  • McLeish AC, Walker KL, Keith RJ, Hart J. 2023. The role of perceived neighborhood cohesion in the association between depressive symptoms and cigarette smoking. Subst Use Misuse 58(10):1295-1301. doi:10.1080/10826084.2023.2215331 PMID:37232382 PMCID:PMC10413331
  • Nault R, Cave MC, Ludewig G, Moseley HN, Pennell KG, Zacharewski TR. 2023. A case for accelerating standards to achieve the FAIR principles of environmental health research experimental data. Environ Health Perspect 131(6):65001. doi:10.1289/EHP11484 PMID:37352010 PMCID:PMC10289218
  • Pavuk M, Rosenbaum PF, Lewin M, Serio TC, Rago P, Cave MC, Birnbaum LS. 2023. Polychlorinated biphenyls, polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, pesticides, and diabetes in the Anniston Community Health Survey follow-up (ACHS II): single exposure and mixture analysis approaches. Sci Total Environ 877:162920. doi:10.1016/j.scitotenv.2023.162920 PMID:36934946
  • Petri BJ, Cave MC, Klinge CM. 2023. Changes in m6A in steatotic liver disease. Genes (Basel) 14(8):1653. doi:10.3390/genes14081653 PMID:37628704 PMCID:PMC10454815
  • Petri BJ, Piell KM, Wahlang B, Head KZ, Andreeva K, Rouchka EC, Cave MC, Klinge CM. 2023. Polychlorinated biphenyls alter hepatic m6A mRNA methylation in a mouse model of environmental liver disease. Environ Res 216:114686. doi:10.1016/j.envres.2022.114686 PMID:36341798 PMCID:PMC10120843
  • Petri BJ, Piell KM, Wahlang B, Head KZ, Rouchka EC, Park JW, Hwang JY, Banerjee M, Cave MC, Klinge CM. 2023. Altered splicing factor and alternative splicing events in a mouse model of diet- and polychlorinated biphenyl-induced liver disease. Environ Toxicol Pharmacol 103:104260. doi:10.1016/j.etap.2023.104260 PMID:37683712 PMCID:PMC10591945
  • Piell KM, Petri BJ, Head KZ, Wahlang B, Xu R, Zhang X, Pan J, Rai SN, Silva Kd, Chariker JH, Rouchka EC, Tan M, Li Y, Cave MC, Klinge CM. 2023. Disruption of the mouse liver epitranscriptome by long-term aroclor 1260 exposure. Environ Toxicol Pharmacol 100:104138. doi:10.1016/j.etap.2023.104138 PMID:37137421 PMCID:PMC10330322
  • Riggs DW, Baumgartner K, Baumgartner R, Boone S, Judd S, Bhatnagar A. 2023. Associations between residential greenness and risk of stroke by ecoregions: The REGARDS Study. Environ Int
  • Wahlang B. 2023. RISING STARS: sex differences in toxicant-associated fatty liver disease. Journal of Endocrinology 258(1):e220247. doi:10.1530/JOE-22-0247 PMID:37074385 PMCID:PMC10330380
  • Wahlang B, Gao H, Rai SN, Keith RJ, McClain CJ, Srivastava S, Cave MC, Bhatnagar A. 2023. Associations between residential volatile organic compound exposures and liver injury markers: The role of biological sex and race. Environ Res 221:115228. doi:10.1016/j.envres.2023.115228 PMID:36610539 PMCID:PMC9957966
  • Walls KM, Hong KU, Hein DW. 2023. Heterocyclic amines reduce insulin-induced AKT phosphorylation and induce gluconeogenic gene expression in human hepatocytes. Arch Toxicol doi:10.1007/s00204-023-03488-2 PMID:37005939 PMCID:PMC10192068
  • Walls KM, Hong KU, Hein DW. 2023. Induction of glucose production by heterocyclic amines is dependent on N-acetyltransferase 2 genetic polymorphism in cryopreserved human hepatocytes. Toxicol Lett 383:192-195. doi:10.1016/j.toxlet.2023.07.002 PMID:37423373
  • Wise JT, Yin X, Ma X, Zhang X, Hein DW. 2023. Stable isotope tracing reveals an altered fate of glucose in n-acetyltransferase 1 knockout breast cancer cells. Genes (Basel) 14(4):843. doi:10.3390/genes14040843 PMID:37107601 PMCID:PMC1013786
  • Xie Z, Chen JY, Gao H, Keith RJ, Bhatnagar A, Lorkiewicz P, Srivastava S. 2023. Global profiling of urinary mercapturic acids using integrated library-guided analysis. Environ Sci Technol 57(29):10563-10573. doi:10.1021/acs.est.2c09554 PMID:37432892
  • Yeager R, Browning MH, Breyer E, Ossola A, Larson LR, Riggs DW, Rigolon A, Chandler C, Fleischer D, Keith RJ, Walker KL, Hart J, Smith T, Bhatnagar A. 2023. Greenness and equity: Complex connections between intra-neighborhood contexts and residential tree planting implementation. Environ Int 176:107955. doi:10.1016/j.envint.2023.107955 PMID:37196566 PMCID:PMC10367429


  • Bhatnagar A. 2022. Cardiovascular effects of particulate air pollution. Annu Rev Med 73:393-406. doi:10.1146/annurev-med-042220-011549 PMID:34644154
  • Bhattacharyya A, Pal S, Mitra R, Rai SN. 2022. Applications of Bayesian shrinkage prior models in clinical research with categorical responses. BMC Med Res Methodol doi:10.1186/s12874-022-01560-6 PMID:35484507 PMCID:PMC9046716
  • Cave MC, Pinkston CM, Rai SN, Wahlang B, Pavuk M, Head KZ, Carswell GK, Nelson GM, Klinge CM, Bell DA, Birnbaum LS, Chorley BN. 2022. Circulating microRNAs, polychlorinated biphenyls, and environmental liver disease in the Anniston Community Health Survey. Environ Health Perspect 130:doi:10.1289/EHP9467 PMID:34989596 PMCID:PMC8734566
  • Coleman CJ, Yeager R, Pond ZA, Riggs DW, Bhatnagar A, Pope III C. 2022. Mortality risk associated with greenness, air pollution, and physical activity in a representative US cohort. Sci Total Environ 824:doi:10.1016/j.scitotenv.2022.153848 PMID:35176374
  • Conklin DJ. 2022. How irritating! Electronic cigarettes not "95 percent safer" than combustible cigarettes: recent mechanistic insights into endothelial dysfunction. Arterioscler Thromb Vasc Biol 42(11):1351-1354. doi:10.1161/ATVBAHA.122.318468 PMID:36288291
  • Doll MA, Hein DW. 2022. 560G A (rs4986782) (R187Q) Single nucleotide polymorphism in arylamine N-acetyltransferase 1 increases affinity for the aromatic amine carcinogens 4-aminobiphenyl and N-hydroxy-4-aminobiphenyl: Implications for cancer risk assessment. Front Pharmacol doi:10.3389/fphar.2022.820082 PMID:35273499 PMCID:PMC8902414
  • Gripshover T, Wahlang B, Head KZ, Young JL, Luo J, Mustafa mT, Kirpich IA, Cave MC. 2022. The environmental pollutant, polychlorinated biphenyl 126, alters liver function in a rodent model of alcohol-associated liver disease. Alcohol Clin Exp Res doi:10.1111/acer.14976 PMID:36377258
  • Habil MR, Doll MA, Hein DW. 2022. Acetyl coenzyme A kinetic studies on N-acetylation of environmental carcinogens by human N-acetyltransferase 1 and its NAT1*14B variant. Front Pharmacol 13:931323. doi:10.3389/fphar.2022.931323 PMID:36386142 PMCID:PMC9650386
  • Habil MR, Salazar-Gonzalez R, Doll MA, Hein DW. 2022. Differences in beta-naphthylamine metabolism and toxicity in Chinese hamster ovary cell lines transfected with human CYP1A2 and NAT2*4, NAT2*5B or NAT2*7B N-acetyltransferase 2 haplotypes. Arch Toxicol doi:10.1007/s00204-022-03367-2 PMID:36040704
  • Habil MR, Salazar-Gonzalez R, Doll MA, Hein DW. 2022. N-acetyltransferase 2 acetylator genotype-dependent N-acetylation and toxicity of the arylamine carcinogen beta-naphthylamine in cryopreserved human hepatocytes. Arch Toxicol doi:10.1007/s00204-022-03381-4 PMID:36112171
  • Halder S, Xie Z, Nantz MH, Fu X. 2022. Integration of a micropreconcentrator with solid-phase microextraction for analysis of trace volatile organic compounds by gas chromatography-mass spectrometry. J Chromatogr A 1673:463083. doi:10.1016/j.chroma.2022.463083 PMID:35508097
  • Hart J, Yeager R, Riggs DW, Fleischer D, Owolabi U, Walker KL, Bhatnagar A, Keith RJ. 2022. The relationship between perceptions and objective measures of greenness. Int J Environ Res Public Health 19(23):16317. doi:10.3390/ijerph192316317 PMID:36498387 PMCID:PMC9736070
  • Hein DW, Doll MA, Habil MR. 2022. Human N-acetyltransferase 1 and 2 differ in affinity towards acetyl-coenzyme A cofactor and N-hydroxy-arylamine carcinogens. Front Pharmacol doi:10.3389/fphar.2022.821133 PMID:35281898 PMCID:PMC8914035
  • Heindel JJ, Howard S, Agay-Shay K, Arrebola J, Audouze K, Babin P, Barouki R, Bansal A, Blanc E, Cave MC, Chatterjee S, Chevalier N, Choudhury M, Collier D, Connolly L, Coumoul X, Garruti G, Gilbertson M, Hoepner L, Holloway A, Howell G, Kassotis CD, Kay M, Kim MJ, Lagadic-Gossmann D, Langouet S, Legrand A, Li Z, Mentec H, Lind L, Lind PM, Lustig R, Martin-Chouly C, Kos VM, Podechard N, Roepke T, Sargis R, Starling AP, Tomlinson CR, Touma C, Vondracek J, vom Saal FS, Blumberg B. 2022. Obesity II: Establishing causal links between chemical exposures and obesity. Biochem Pharmacol doi:10.1016/j.bcp.2022.115015 PMID:35395240 PMCID:PMC9124454
  • Lorkiewicz P, Keith RJ, Lynch J, Jin L, Theis W, Krivokhizhina T, Riggs D, Bhatnagar A, Srivastava S, Conklin DJ. 2022. Electronic cigarette solvents, JUUL e-liquids, and biomarkers of exposure: In vivo evidence for acrolein and glycidol in e-cig-derived aerosols. Chem Res Toxicol doi:10.1021/acs.chemrestox.1c00328 PMID:35044764
  • Lustig R, Collier D, Kassotis CD, Roepke T, Kim MJ, Blanc E, Barouki R, Bansal A, Cave MC, Chatterjee S, Choudhury M, Gilbertson M, Lagadic-Gossmann D, Howard S, Lind L, Tomlinson CR, Vondracek J, Heindel JJ. 2022. Obesity I: Overview and molecular and biochemical mechanisms. Biochem Pharmacol 199:doi:10.1016/j.bcp.2022.115012 PMID:35393120 PMCID:PMC9050949
  • McLeish AC, Smith T, Riggs DW, Hart J, Walker KL, Keith RJ, Anderson L, Sithu ID, Pinilla-Baquero J, Srivastava S, Bhatnagar A. 2022. Community-based evaluation of the associations between well-being and cardiovascular disease risk. J Am Heart Assoc 11(22):e027095. doi:10.1161/JAHA.122.027095 PMID:36370026
  • Petri BJ, Piell KM, Wahlang B, Head KZ, Andreeva K, Rouchka EC, Pan J, Rai SN, Cave MC, Klinge CM. 2022. Multiomics analysis of the impact of polychlorinated biphenyls on environmental liver disease in a mouse model. Environ Toxicol Pharmacol 94:doi:10.1016/j.etap.2022.103928 PMID:35803474
  • Petriello MC, Mottaleb MA, Serio TC, Balyan B, Cave MC, Birnbaum LS, Morris AJ. 2022. Serum concentrations of legacy and emerging per- and polyfluoroalkyl substances in the Anniston Community Health Surveys (ACHS I and ACHS II). Environ Int 158:106907. doi:10.1016/j.envint.2021.106907 PMID:34763231
  • Rai SN, Das S, Pan J, Mishra DC, Fu X. 2022. Multigroup prediction in lung cancer patients and comparative controls using signature of volatile organic compounds in breath samples. PLoS One 17(11):e0277431. doi:10.1371/journal.pone.0277431 PMID:36449484 PMCID:PMC9710764
  • Riggs DW, Malovichko MV, Gao H, McGraw KE, Taylor BS, Krivokhizhina T, Rai SN, Keith RJ, Bhatnagar A, Srivastava S. 2022. Environmental exposure to volatile organic compounds is associated with endothelial injury. Toxicol Appl Pharmacol 437:115877. doi:10.1016/j.taap.2022.115877 PMID:35045333
  • Shuck B, Hart J, Walker KL, Rai J, Srivastava S, Srivastava S, Rai SN, Bhatnagar A, Keith RJ. 2022. Workplace culture and biomarkers of health risk. Int J Environ Res Public Health 19(19):11920. doi:10.3390/ijerph191911920 PMID:36231223 PMCID:PMC9565767
  • Srivastava S. 2022. Effects of environmental polycyclic aromatic hydrocarbons exposure and pro-inflammatory activity on type 2 diabetes mellitus in US adults. Open J Air Pollut 11(2):29-46. doi:10.4236/ojap.2022.112003 PMID:35844632 PMCID:PMC9283753
  • Wahlang B, Gripshover T, Gao H, Krivokhizhina T, Keith RJ, Sithu ID, Rai SN, Bhatnagar A, McClain CJ, Srivastava S, Cave MC. 2022. Associations between residential exposure to volatile organic compounds and liver injury markers. Toxicol Sci 185(1):doi:10.1093/toxsci/kfab119 PMID:34668566 PMCID:PMC8714366
  • Wise JT, Salazar-Gonzalez R, Habil MR, Doll MA, Hein DW. 2022. Expression of arylamine N-acetyltransferase 2 activity in immortalized human bronchial epithelial cells. Toxicol Appl Pharmacol 442:115993. doi:10.1016/j.taap.2022.115993 PMID:35353990
  • Wise JT, Salazar-Gonzalez R, Walls KM, Doll MA, Habil MR, Hein DW. 2022. Hexavalent chromium increases the metabolism and genotoxicity of aromatic amine carcinogens 4-aminobiphenyl and B-naphthylamine in immortalized human lung epithelial cells. Toxicol Appl Pharmacol 449:doi:10.1016/j.taap.2022.116095 PMID:35662664
  • Young JL, Cave MC, Xu Q, Kong M, Xu J, Lin Q, Tan Y, Cai L. 2022. Whole life exposure to low dose cadmium alters diet-induced NAFLD. Toxicol Appl Pharmacol 436:doi:10.1016/j.taap.2021.115855 PMID:34990729 PMCID:PMC8796138


  • Coleman CJ, Yeager R, Riggs DW, Coleman NC, Garcia GR, Bhatnagar A, Pope CA. 2021. Greenness, air pollution, and mortality risk: A US cohort study of cancer patients and survivors. Environ Int 157:106797. doi:10.1016/j.envint.2021.106797 PMID:34332301
  • Das S, Rai A, Merchant ML, Cave MC, Rai SN. 2021. A comprehensive survey of statistical approaches for differential expression analysis in single-cell RNA sequencing studies. Genes (Basel) 12(12):1947. doi:10.3390/genes12121947 PMID:34946896 PMCID:PMC8701051
  • Das S, Rai SN. 2021. SwarnSeq: An improved statistical approach for differential expression analysis of single-cell RNA-seq data. Genomics 113:1308-1324. doi:10.1016/j.ygeno.2021.02.014 PMID:33662531
  • Guardiola JJ, Hardesty JE, Beier JI, Prough RA, McClain CJ, Cave MC. 2021. Plasma metabolomics analysis of polyvinyl chloride workers identifies altered processes and candidate biomarkers for hepatic hemangiosarcoma and its development. Int J Mol Sci 22:doi:10.3390/ijms22105093 PMID:34065028 PMCID:PMC8150673
  • Haberzettl P, Jin L, Riggs DW, Zhao J, O'Toole TE, Conklin DJ. 2021. Fine particulate matter air pollution and aortic perivascular adipose tissue: Oxidative stress, leptin, and vascular dysfunction. Physiol Rep 9:e14980. doi:10.14814/phy2.14980 PMID:34327871 PMCID:PMC8322754
  • Hardesty JE, Wahlang B, Prough RA, Head KZ, Wilkey D, Merchant ML, Shi H, Jin J, Cave MC. 2021. Effect of epidermal growth factor treatment and polychlorinated biphenyl exposure in a dietary-exposure mouse model of steatohepatitis. Environ Health Perspect 129:37010. doi:10.1289/EHP8222 PMID:33788613 PMCID:PMC8011667
  • Jin J, Wahlang B, Thapa M, Head KZ, Hardesty JE, Srivastava S, Merchant ML, Rai SN, Prough RA, Cave MC. 2021. Proteomics and metabolic phenotyping define principal roles for the aryl hydrocarbon receptor in mouse liver. Acta Pharm Sin B 11:3806-3819. doi:10.1016/j.apsb.2021.10.014 PMID:35024308 PMCID:PMC8727924
  • Jin L, Conklin DJ. 2021. A novel evaluation of endothelial dysfunction ex vivo: Teaching an Old Drug a New Trick. Physiol Rep 9(21):e15120. doi:10.14814/phy2.15120 PMID:34755498 PMCID:PMC8579072
  • Jin L, Lorkiewicz P, Xie Z, Bhatnagar A, Srivastava S, Conklin DJ. 2021. Acrolein but not its metabolite, 3-Hydroxypropylmercapturic acid (3HPMA), activates vascular transient receptor potential Ankyrin-1 (TRPA1): Physiological to toxicological implications. Toxicol Appl Pharmacol 426:115647. doi:10.1016/j.taap.2021.115647 PMID:34271065 PMCID:PMC8343963
  • Jin L, Lynch J, Richardson A, Lorkiewicz P, Srivastava S, Theis W, Shirk G, Hand A, Bhatnagar A, Srivastava S, Conklin DJ. 2021. Electronic cigarette solvents, pulmonary irritation and endothelial dysfunction: role of acetaldehyde and formaldehyde. Am J Physiol Heart Circ Physiol doi:10.1152/ajpheart.00878.2020 PMID:33543686
  • Klinge CM, Piell KM, Petri BJ, He L, Zhang X, Pan J, Rai SN, Andreeva K, Rouchka EC, Wahlang B, Beier JI, Cave MC. 2021. Combined exposure to polychlorinated biphenyls and high-fat diet modifies the global epitranscriptomic landscape in mouse liver. Environ Epigenet 7:doi:10.1093/eep/dvab008 PMID:34548932 PMCID:PMC8448424
  • Linder MW, Egger ME, Van Meter T, Rai SN, Valdes R, Hall MB, Wu X, Alghamdi N, Chesney JA. 2021. Longitudinal relationship between Idylla plasma ctBRAF V600 mutation detection and tumor burden in patients with metastatic melanoma. Mol Diagn Ther 25:361-371. doi:10.1007/s40291-021-00528-4 PMID:33970440
  • Malovichko MV, Abplanalp WT, McFall SA, Taylor BS, Wickramasinghe NS, Sithu ID, Zelko I, Uchida S, Hill BG, Sutaria S, Nantz MH, Bhatnagar A, Conklin DJ, O'Toole TE, Srivastava S. 2021. Subclinical markers of cardiovascular toxicity of benzene inhalation in mice. Toxicol Appl Pharmacol 431(9):115742. doi:10.1016/j.taap.2021.115742 PMID:34624356 PMCID:PMC8647905
  • McGraw KE, Riggs DW, Rai SN, Navas-Acien A, Xie Z, Lorkiewicz P, Lynch J, Zafar N, Krishnasamy SS, Taylor KC, Conklin DJ, DeFilippis A, Srivastava S, Bhatnagar A. 2021. Exposure to volatile organic compounds - acrolein, 1,3-butadiene, and crotonaldehyde - is associated with vascular dysfunction. Environ Res 196:110903. doi:10.1016/j.envres.2021.110903 PMID:33636185 PMCID:PMC8119348
  • Pfeiffer JA, Hart J, Wood LA, Bhatnagar A, Keith RJ, Yeager R, Smith T, Tomlinson M, Gilkey D, Kerstiens S, Gao H, Srivastava S, Walker KL. 2021. The importance of urban planning: Views of greenness and open space is reversely associated with self-reported views and depressive symptoms. Popul Med 3:20. doi:10.18332/popmed/139173 PMID:34368779 PMCID:PMC8341459
  • Racette BA, Nelson G, Dlamini WW, Hershey T, Prathibha P, Turner JR, Checkoway H, Sheppard L, Nielsen SS. 2021. Depression and anxiety in a manganese-exposed community. Neurotoxicology 85:doi:10.1016/j.neuro.2021.05.017 PMID:34087333 PMCID:PMC8635218
  • Riggs DW, Yeager R, Conklin DJ, DeJarnett N, Keith RJ, DeFilippis A, Rai SN, Bhatnagar A. 2021. Residential proximity to greenness mitigates the hemodynamic effects of ambient air pollution. Am J Physiol Heart Circ Physiol 320(3):doi:10.1152/ajpheart.00689.2020 PMID:33416460 (ahead of print)
  • Srivastava DK, George E, Lu Z, Rai SN. 2021. Impact of unequal censoring and insufficient follow-up on comparing survival outcomes: Applications to clinical studies. Stat Methods Med Res 30:PMID:34232837
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