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Project Publications: Texas A&M University: Single Cell, Multi-Parametric High Throughput Platform to Classify Endocrine Disruptor Potential of Mixtures

Superfund Research Program

Single Cell, Multi-Parametric High Throughput Platform to Classify Endocrine Disruptor Potential of Mixtures

Project Leader: Michael A. Mancini (Baylor College of Medicine)
Co-Investigators: Fabio Stossi (Baylor College of Medicine), Adam T. Szafran (Baylor College of Medicine)
Grant Number: P42ES027704
Funding Period: 2017-2022
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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Publications

2020

  • Stossi F, Dandekar RD, Mancini MG, Gu G, Fuqua SA, Nardone A, De Angelis C, Fu X, Schiff R, Bedford MT, Xu W, Johansson HE, Stephan C, Mancini MA. 2020. Estrogen-induced transcription at individual alleles is independent of receptor level and active conformation but can be modulated by coactivators activity. Nucleic Acids Res 48:1800-1810. doi:10.1093/nar/gkz1172 PMID:31930333

2019

  • Di Bona M, Mancini MA, Mazza D, Vicidomini G, Diaspro A, Lanzano L. 2019. Measuring Mobility in Chromatin by Intensity-Sorted FCS. Biophys J 116(6):P987-999. doi:10.1016/j.bpj.2019.02.003 PMID:30819566 PMCID:PMC6428914
  • Kuthurua S, Szafran AT, Stossi F, Mancini MA, Rao A. 2019. Leveraging image-derived phenotypic measurements for drug-target interaction predictions. Cancer Inform doi:10.1177/1176935119856595 PMID:31217689 PMCID:PMC6563400
  • Mukherjee R, Onel M, Beykal B, Szafran AT, Stossi F, Mancini MA, Zhou L, Wright FA, Pistikopoulos EN. 2019. Development of the Texas A&M Superfund Research Program computational platform for data integration, visualization, and analysis. Computer Aided Chemical Engineering 46:967-972. doi:10.1016/B978-0-12-818634-3.50162-4 PMID:31612156 PMCID:PMC6791821
  • Stossi F, Dandekar RD, Johnson H, Lavere P, Foulds CE, Mancini MG, Mancini MA. 2019. Tributyltin chloride (TBT) induces RXRA down-regulation and lipid accumulation in human liver cells. PLoS One 14:e0224405. doi:10.1371/journal.pone.0224405 PMID:31710612 PMCID:PMC6844554
  • Stossi F, Dandekar RD, Mancini MG, Gu G, Fuqua SA, Nardone A, De Angelis C, Fu X, Schiff R, Bedford MT, Xu W, Johansson HE, Stephan C, Mancini MA. 2019. Methyltransferases buffer E2-induced transcription at individual alleles. Nucleic Acids Res
  • Xia J, Chiu L, Nehring R, Bravo Nunez M, Mei Q, Perez M, Zhai Y, Fitzgerald D, Pribis J, Wang Y, Hu C, Powell R, LaBonte S, Jalali A, Matadamas Guzman M, Lentzsch A, Szafran AT, Joshi M, Richters M, Gibson J, Frisch R, Hastings P, Bates D, Queitsch C, Hilsenbeck SG, Coarfa C, Hu JC, Siegele DA, Scott KL, Liang H, Mancini MA, Herman C, Miller KM, Rosenberg SM. 2019. Bacteria-to-human protein networks reveal origins of endogenous DNA damage. Cell 176(1-2):127-143. doi:10.1016/j.cell.2018.12.008 PMID:30633903 PMCID:PMC6344048

2018

  • Chowdhury P, Powell R, Stephan C, Uray I, Talley T, Karki M, Tripathi D, Park Y, Mancini MA, Davies P, Dere R. 2018. Bexarotene - a novel modulator of AURKA and the primary cilium in VHL-deficient cells. Journal of Cell Science 131(24):doi:10.1242/jcs.219923 PMID:30518623 PMCID:PMC6307881

2017

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