Superfund Research Program

Data Management and Analysis Core

Project Leader: Efstratios N. Pistikopoulos
Grant Number: P42ES027704
Funding Period: 2022-2027

Project-Specific Links

Publications

2024

• Ford L, Lin H, Tsai H, Zhou Y, Wright FA, Sedykh A, Shah R, Chiu WA, Rusyn I. 2024. Hazard and risk characterization of 56 structurally diverse PFAS using a targeted battery of broad coverage assays using six human cell types. Toxicology 503:153763. doi:10.1016/j.tox.2024.153763 PMID:38423244
• Kvasnicka J, Aurisano N, von Borries K, Lu E, Fantke P, Jolliet O, Wright FA, Chiu WA. 2024. Two-stage machine learning-based approach to predict points of departure for human noncancer and developmental/reproductive effects. Environ Sci Technol doi:10.1021/acs.est.4c00172 PMID:38693844
• Tsai H, Ford L, Burnett SD, Dickey AN, Wright FA, Chiu WA, Rusyn I. 2024. Informing hazard identification and risk characterization of environmental chemicals by combining transcriptomic and functional data from human-induced pluripotent stem-cell-derived cardiomyocytes. Chem Res Toxicol 37(8):1428-1444. doi:10.1021/acs.chemrestox.4c00193 PMID:39046974
• Tsai H, Ford L, Chen Z, Dickey AN, Wright FA, Rusyn I. 2024. Risk-based prioritization of PFAS using phenotypic and transcriptomic data from human induced pluripotent stem cell-derived hepatocytes and cardiomyocytes. ALTEX doi:10.14573/altex.2311031 PMID:38429992

2023

• Aghayev Z, Szafran AT, Tran A, Ganesh HS, Stossi F, Zhou L, Mancini MA, Pistikopoulos EN, Beykal B. 2023. Machine learning methods for endocrine disrupting potential identification based on single-cell data. Chem Eng Sci 281:119086. doi:10.1016/j.ces.2023.119086 PMID:37637227 PMCID:PMC10448728
• Aghayev Z, Walker GF, Iseri F, Ali M, Szafran AT, Stossi F, Mancini MA, Pistikopoulos EN, Beykal B. 2023. Binary classification of the endocrine disrupting chemicals by artificial neural networks. ESCAPE 52:2631-2636. doi:10.1016/b978-0-443-15274-0.50418-2 PMID:37575176 PMCID:PMC1041341
• Cordova AC, Dodds J, Tsai H, Lloyd D, Roman-Hubers AT, Wright FA, Chiu WA, McDonald TJ, Zhu R, Newman G, Rusyn I. 2023. Application of ion mobility spectrometry-mass spectrometry for compositional characterization and fingerprinting of a library of diverse crude oil samples. Environ Toxicol Chem doi:10.1002/etc.5727 PMID:37530422
• Cordova AC, Klaren WD, Ford L, Grimm FA, Baker ES, Zhou Y, Wright FA, Rusyn I. 2023. Integrative chemical-biological grouping of complex high production volume substances from lower olefin manufacturing streams. Toxics 11(7):586. doi:10.3390/toxics11070586 PMID:37505552 PMCID:PMC10385386
• Perez Gomez AA, Wang M, Kochan K, Amstalden K, Young CR, Welsh CJ, Phillips TD, Brinkmeyer-Langford CL. 2023. C57BL/6J mice exposed to perfluorooctanoic acid demonstrate altered immune responses and increased seizures after Theiler's murine encephalomyelitis virus infection. Front Immunol 14:1228509. doi:10.3389/fimmu.2023.1228509 PMID:37600798 PMCID:PMC10434537
• Rusyn I, Wright FA. 2023. Ten years of using key characteristics of human carcinogens to organize and evaluate mechanistic evidence in IARC Monographs on the identification of carcinogenic hazards to humans: Patterns and associations. Toxicol Sci doi:10.1093/toxsci/kfad134 PMID:38141214
• Sakolish C, Moyer HL, Tsai H, Ford L, Dickey AN, Wright FA, Han G, Bajaj P, Baltazar MT, Carmichael PL, Stanko JP, Ferguson SS, Rusyn I. 2023. Analysis of reproducibility and robustness of a renal proximal tubule microphysiological system OrganoPlate 3-lane 40 for in vitro studies of drug transport and toxicity. Toxicol Sci doi:10.1093/toxsci/kfad080 PMID:37555834
• Tsai H, House JS, Wright FA, Chiu WA, Rusyn I. 2023. A tiered testing strategy based on in vitro phenotypic and transcriptomic data for selecting representative petroleum UVCBs for toxicity evaluation in vivo. Toxicol Sci doi:10.1093/toxsci/kfad041 PMID:37079747 PMCID:PMC10230285

2022

• Beykal B, Diangelakis NA, Pistikopoulos EN. 2022. Continuous-time surrogate models for data-driven dynamic optimization. ESCAPE 51:205-210. doi:10.1016/b978-0-323-95879-0.50035-7 PMID:36622647 PMCID:PMC9823268
• Zhou Y, Gallins P, Etheridge AS, Jima DD, Scholl EH, Wright FA, Innocenti F. 2022. A resource for integrated genomic analysis of the human liver. Sci Rep 12(1):15151. doi:10.1038/s41598-022-18506-z PMID:36071064 PMCID:PMC9452507