Program Publications: University of Alabama at Birmingham: Impact of Airborne Heavy Metals on Lung Disease and the Environment

Superfund Research Program

Impact of Airborne Heavy Metals on Lung Disease and the Environment

Center Director: Veena Antony
Grant Number: P42ES027723
Funding Period: 2020-2025

Program Links

Publications

2023

• Goswami A, Adkins-Jablonsky SJ, Filho MM, Shilling MD, Dawson A, Heiser S, O'Connor A, Walker M, Roberts Q, Morris JJ. 2023. Heavy metal pollution impacts soil bacteria community structure and antimicrobial resistance at the Birmingham 35th Avenue Superfund site. Microbiol Spectr 11(2):doi:10.1128/spectrum.02426-22 PMID:36951567 PMCID:PMC1010105
• Pillai R, Thomas V. 2023. Plasma surface engineering of natural and sustainable polymeric derivatives and their potential applications. Polymers 15(2):400. doi:10.3390/polym15020400 PMID:36679280 PMCID:PMC9863272
• Surolia R, Li FJ, Dsouza K, Zeng H, Singh P, Stephens CT, Guo Y, Wang Z, Kashyap M, Srivastava RK, Gonzalez ML, Benson P, Kumar A, Kim H, Kim Y, Ahmad A, Athar M, Antony V. 2023. Cutaneous exposure to arsenicals is associated with development of constrictive bronchitis in mice. Am J Respir Cell Mol Biol 68(5):485-497. doi:10.1165/rcmb.2022-0321MA PMID:36780670

2022

• Bowers MS, Canalias C, Mirov S, Nilsson J, Saraceno C, Schunemann PG. 2022. Feature issue introduction: advanced solid-state lasers. Opt Express 30(12):20762-20766. doi:10.1364/OE.464517 PMID:36224813
• Chang Z, Fang L, Fedorov V, Geiger C, Ghimire S, Heide C, Ishii N, Itatani J, Joshi C, Kobayashi Y, Kumar P, Marra A, Mirov S, Petrushina I, Polyanskiy M, Reis DA, Tochitsky S, Vasilyev S, Wang L, Wu Y, Zhou F. 2022. Intense infrared lasers for strong-field science. Adv Opt Photonics 14(4):652-782. doi:10.1364/AOP.454797
• Cui H, Xie N, Banerjee S, Dey T, Liu R, Antony V, Sanders YY, Adams TS, Gomez JL, Thannickal V, Kaminski N. 2022. CD38 mediates lung fibrosis by promoting alveolar epithelial cell aging. Am J Respir Crit Care Med 206(4):459-475. doi:10.1164/rccm.202109-2151OC PMID:35687485
• Curtiss ML, Deshane J. 2022. Stick a Fork in Me; I'm Done: Epithelial Cell Expression of ORMDL Sphingolipid Biosynthesis Regulator 3 Mediates Autophagic Cell Death. Am J Respir Cell Mol Biol 66(6):593-595. doi:10.1165/rcmb.2022-0023ED PMID:35377833 PMCID:PMC9163635
• Floyd EL, Oh J, Sapag K, Oni TM, Lungu C. 2022. Photothermal desorption of toluene from carbonaceous substrates using light flash. Nanomaterials 12(4):662. doi:10.3390/nano12040662 PMID:35214991 PMCID:PMC8876870
• Goliwas KF, Kashyap M, Khan J, Sinha R, Weng Z, Oak AS, Jin L, Atigadda V, Lee MB, Elmets CA, Mukhtar MS, Raman C, Deshane J, Athar M. 2022. Ex vivo culture models of hidradenitis suppurativa for defining molecular pathogenesis and treatment efficacy of novel drugs. Inflammation 45(3):1388-1401. doi:10.1007/s10753-022-01629-w PMID:35301634 PMCID:PMC9940461
• Goliwas KF, Wood AM, Simmons CS, Khan R, Khan SA, Wang Y, Berry JL, Athar M, Mobley JA, Kim Y, Thannickal V, Harrod KS, Donahue JM, Deshane J. 2022. Local SARS-CoV-2 peptide-specific immune responses in lungs of convalescent and uninfected human subjects. medRxiv doi:10.1101/2021.09.02.21263042 PMID:34518842 PMCID:PMC8437319
• He C, Carter AB. 2022. CRTH2 in pulmonary fibrosis: Friend or foe?. Am J Respir Cell Mol Biol 67(2):145-146. doi:10.1165/rcmb.2022-0232ED PMID:35675551 PMCID:PMC9348569
• Jones SR, Shedd J, Oh J, Lungu C. 2022. Evaluating the effects of modified windscreens on organic vapor monitor performance. Environ Health Insights 16:doi:10.1177/11786302221078430 PMID:35173446 PMCID:PMC8842150
• Karki K, Fedorov V, Martyshkin D, Mirov S. 2022. High energy mechanically Q-switched Er:YAG laser operating at 2940 nm. Proc SPIE Int Soc Opt Eng doi:10.1117/12.2623365
• Larson-Casey JL, Carter AB. 2022. Does UCP2 couple hyperoxia to lung injury?. Am J Respir Cell Mol Biol 66(3):250-251. doi:10.1165/rcmb.2021-0480ED PMID:34905723 PMCID:PMC8937246
• Li FJ, Surolia R, Singh P, Dsouza K, Stephens CT, Wang Z, Liu R, Bae S, Kim Y, Athar M, Dransfield MT, Antony V. 2022. Fibrinogen mediates cadmium-induced macrophage activation and serves as a predictor of cadmium exposure in chronic obstructive pulmonary disease. Am J Physiol Lung Cell Mol Physiol doi:10.1152/ajplung.00475.2021 PMID:35200041
• Rangarajan S, Locy ML, Chanda D, Kurundkar AR, Kurundkar D, Larson-Casey JL, Londono P, Bagchi RA, Deskin B, Elajaili H, Nozik ES, Deshane J, Zmijewski J, Eickelberg O, Thannickal V. 2022. Mitochondrial uncoupling protein-2 reprograms metabolism to induce oxidative stress and myofibroblast senescence in age-associated lung fibrosis. Aging Cell 21(9):e13674. doi:10.1111/acel.13674 PMID:35934931 PMCID:PMC9470902
• Smolski V, Moskalev I, Vasilyev S, Peppers J, Mirov M, Fedorov V, Martyshkin D, Mirov S. 2022. High-energy Q-switched 120 mJ Ho:YAG lasers at 500 Hz repetition rate. Proc SPIE Int Soc Opt Eng doi:10.1117/12.2623264
• Srivastava RK, Wang Y, Khan J, Muzaffar S, Lee MB, Weng Z, Croutch C, Agarwal A, Deshane J, Athar M. 2022. Role of hair follicles in the pathogenesis of arsenical-induced cutaneous damage. Ann N Y Acad Sci 1515(1):168-183. doi:10.1111/nyas.14809 PMID:35678766 PMCID:PMC9531897
• Stephens CT, Kim Y, Ramachandran R, Baskin ML, Antony V, Bae S. 2022. Disparities in healthcare utilization: Superfund site vs. neighboring comparison site. Int J Environ Res Public Health 19(15):9271. doi:10.3390/ijerph19159271 PMID:35954629 PMCID:PMC9367949
• Stiles A, Tison T, Pruitt L, Vaidya U. 2022. Photoinitiator selection and concentration in photopolymer formulations towards large-format additive manufacturing. Polymers 14(13):2708. doi:10.3390/polym14132708 PMID:35808752 PMCID:PMC9268840
• Surolia R, Antony V. 2022. Pathophysiological role of vimentin intermediate filaments in lung diseases. Front Cell Dev Biol doi:10.3389/fcell.2022.872759 PMID:35573702 PMCID:PMC9096236
• Vasilyev S, Smolski V, Peppers J, Moskalev I, Mirov M, Barnakov Y, Mirov S. 2022. High-power mid-IR Cr:ZnS-based frequency combs for spectroscopy imaging and sensing. Proc SPIE Int Soc Opt Eng doi:10.1117/12.2622970
• Vijayan VM, Walker M, Pilllai RR, Moreno GH, Vohra YK, Morris JJ, Thomas V. 2022. Plasma electroless reduction: A green process for designing metallic nanostructure interfaces onto polymeric surfaces and 3D scaffolds. ACS Appl Mater Interfaces 14(22):25065-25079. doi:10.1021/acsami.2c01195 PMID:35638266
• Wang H, Khattar V, Hensel JA, Ashton R, Lu Y, Sorace AG, Wang Y, Deshane J, Mieher JL, Deivanayagam C, Ponnazhagan S. 2022. Systemic checkpoint blockade by PD-L1 single-chain antibody confers potent antitumor immunity and long-term survival. Mol Cancer Ther 21(11):1710-1721. doi:10.1158/1535-7163.MCT-22-0010 PMID:36031328 PMCID:PMC963356
• Wasti S, Kore S, Yeole P, Tekinalp H, Ozcan S, Vaidya U. 2022. Bamboo fiber reinforced polypropylene composites for transportation applications. Front Mater 9:doi:10.3389/fmats.2022.967512

2021

• Cao R, To K, Kachour N, Beever A, Owens J, Sathananthan A, Singh P, Kolloli A, Subbian S, Venketaraman V. 2021. Everolimus-induced effector mechanism in macrophages and survivability of Erdman, CDC1551 and HN878 strains of Mycobacterium tuberculosis infection. Biomol Concepts 12(1):46-54. doi:10.1515/bmc-2021-0006 PMID:34062056 PMCID:PMC8993225
• Chanda D, Rehan M, Smith S, Dsouza K, Bernard K, Memula V, Kojima K, Mobley JA, Benavides G, Darley-Usmar VM, Kim Y, Zmijewski J, Deshane J, De Langhe S, Thannickal V. 2021. Mesenchymal stromal cell aging impairs the self-organizing capacity of lung alveolar epithelial stem cells. Elife doi:10.7554/eLife.68049 PMID:34528872 PMCID:PMC8445616
• Gu L, Surolia R, Larson-Casey JL, He C, Davis D, Kang J, Antony V, Carter AB. 2021. Targeting Cpt1a-Bcl-2 interaction modulates apoptosis resistance and fibrotic remodeling. Cell Death Differ 29(1):doi:10.1038/s41418-021-00840-w PMID:34413485 (ahead of print)
• Karki K, Fedorov V, Martyshkin D, Mirov S. 2021. High energy (0.8 J) mechanically Q-switched 2.94 micron Er:YAG laser. Opt Express 29(3):4287-4295. doi:10.1364/OE.417301 PMID:33771011 PMCID:PMC7920523
• Khan SA, Goliwas KF, Deshane J. 2021. Sphingolipids in lung pathology in the coronavirus disease era: a review of sphingolipid involvement in the pathogenesis of lung damage. Front Physiol 12:760638. doi:10.3389/fphys.2021.760638 PMID:34690821 PMCID:PMC8531546
• Kolloli A, Kumar R, Singh P, Narang A, Kaplan G, Sigal A, Subbian S. 2021. Aggregation state of Mycobacterium tuberculosis impacts host immunity and augments pulmonary disease pathology. Commun Biol 4:doi:10.1038/s42003-021-02769-9 PMID:34732811 PMCID:PMC8566596
• Kore S, Spencer R, Ghossein H, Slaven L, Knight D, Unser J, Vaidya U. 2021. Performance of hybridized bamboo-carbon fiber reinforced polypropylene composites processed using wet laid technique. Compos Pt C-Open Access 6:doi:10.1016/j.jcomc.2021.100185
• Kore S, Theodore M, Pillai R, Thomas V, Vaidya U. 2021. Improvement of interfacial adhesion of unidirectional textile grade carbon fiber (TCF) with unsized, epoxy and urethane sizing reinforced in thermoset urethane composites. Mater Today Commun 28(10):
• Kore S, Theodore M, Vaidya U. 2021. Effect of the segmental structure of thermoplastic polyurethane (hardness) on the interfacial adhesion of textile-grade carbon fiber composites. ACS Appl. Polym. Mater 3:
• Larson-Casey JL, Gu L, Davis D, Cai G, Ding Q, He C, Carter AB. 2021. Post-translational regulation of PGC-1(alpha) modulates fibrotic repair. FASEB J 35:e21675. doi:10.1096/fj.202100339R PMID:34038004 PMCID:PMC8252570
• Larson-Casey JL, Gu L, Kang J, Dhyani A, Carter AB. 2021. NOX4 regulates macrophage apoptosis resistance to induce fibrotic progression. J Biol Chem 297:12. doi:10.1016/j.jbc.2021.100810 PMID:34023385 PMCID:PMC8214193
• Li FJ, Surolia R, Li H, Wang Z, Liu G, Kulkarni T, Massicano AV, Mobley JA, Mondal S, de Andrade JA, Coonrod SA, Thompson PR, Wille K, Lapi SE, Athar M, Thannickal V, Carter AB, Antony V. 2021. Citrullinated vimentin mediates development and progression of lung fibrosis. Sci Transl Med 13(585):doi:10.1126/scitranslmed.aba2927 PMID:33731433
• Martyshkin D, Karki K, Fedorov V, Mirov S. 2021. Room temperature, nanosecond, 60 mJ/pulse Fe:ZnSe master oscillator power amplifier system operating at 3.8-5.0 microns. Opt Express 29(2):2387-2393. doi:10.1364/OE.416574 PMID:33726434 PMCID:PMC7920527
• Mukundan S, Singh P, Shah A, Kumar R, O'Neill KC, Carter CL, Russell D, Subbian S, Parekkadan B. 2021. In vitro miniaturized tuberculosis spheroid model. Biomedicine 9(9):1209. doi:10.3390/biomedicines9091209 PMID:34572395 PMCID:PMC8470281
• Petersen A, Taccheo S, Mirov S, Nilsson J, Pask H, Saraceno C, Wetter N, Wu R. 2021. Focus issue introduction: Advanced Solid-State Lasers 2020. Opt Mater Express 11(4):952-954. doi:10.1364/OE.423636 PMID:33820284
• Pigeon J, Tovey D, Tochitsky S, Louwrens G, Ben-Zvi I, Martyshkin D, Fedorov V, Karki K, Mirov S, Joshi C. 2021. Resonant nonlinear refraction of 4-5 micron light in CO and CO2 gas. Physical Review A 104:doi:10.1103/PhysRevA.104.043519
• Ranjan P, Thomas V, Kumar P. 2021. 2D materials as a diagnostic platform for the detection and sensing of the SARS-CoV-2 virus: A bird's-eye view. J Mater Chem B Mater Biol Med 9(23):doi:10.1039/d1tb00071c PMID:34013310 (ahead of print)
• Rehan M, Kurundkar D, Kurundkar AR, Logsdon NJ, Smith S, Chanda D, Bernard K, Sanders YY, Deshane J, Dsouza K, Rangarajan S, Zmijewski J, Thannickal V. 2021. Restoration of SIRT3 gene expression by airway delivery resolves age-associated persistent lung fibrosis in mice. Nat Aging 1(2):205-217. doi:10.1038/s43587-021-00027-5 PMID:34386777 PMCID:PMC8357317
• Ru Q, Kawamori T, Schunemann PG, Vasilyev S, Mirov S, Vodopyanov KL. 2021. Two-octave-wide (3-12 micron) subharmonic produced in a minimally dispersive optical parametric oscillator cavity. Opt Lett 46(4):709-712. doi:10.1364/OL.403910 PMID:33577495
• Shedd J, Kuehster WW, Ranjit S, Hauser AJ, Floyd EL, Oh J, Lungu C. 2021. Determining the thermal properties of buckypapers used in photothermal desorption. ACS Omega 6(8):5415-5422. doi:10.1021/acsomega.0c05613 PMID:33681581 PMCID:PMC7931396
• Subedi S, Fedorov V, Mirov S, Markham M. 2021. Spectroscopy of GR1 centers in synthetic diamonds. Opt Mater Express 11(3):757-765. doi:10.1364/OME.417432
• Surolia R, Li FJ, Wang Z, Kashyap M, Srivastava RK, Traylor AM, Singh P, Dsouza K, Kim H, Pittet J, Zmijewski J, Agarwal A, Athar M, Ahmad A, Antony V. 2021. NETosis in the pathogenesis of acute lung injury following cutaneous chemical burns. JCI Insight 6(10):e147564. doi:10.1172/jci.insight.147564 PMID:34027893 PMCID:PMC826236
• Tovey D, Pigeon J, Tochitsky S, Louwrens G, Ben-Zvi I, Martyshkin D, Fedorov V, Karki K, Mirov S, Joshi C. 2021. Lasing in 15 atm CO2 cell optically pumped by a Fe:ZnSe laser. Opt Express 29(20):31455-31464. doi:10.1364/OE.434670 PMID:34615237
• Uday V, Hopkins J. 2021. IACMI - The Composites Institute efforts in current and post-COVID-19 manufacturing era-innovations and sustainability. ASTM 5(1):doi:10.1520/ssms20200070
• Vasilyev S, Gu J, Mirov M, Barnakov Y, Moskalev I, Smolski V, Peppers J, Kolesik M, Mirov S, Gapontsev V. 2021. Low-threshold supercontinuum generation in polycrystalline media. Journal of the Optical Society of America B 38(5):1625-1633. doi:10.1364/JOSAB.417485
• Vasilyev S, Moskalev I, Smolski V, Peppers J, Merov M, Fedorov V, Barnakov Y, Martyshkin D, Mirov S, Gapontsev V. 2021. Kerr-lens mode-locked Cr:ZnS oscillator reaches the spectral span of an optical octave. Opt Express 29:doi:10.1364/OE.411984 PMID:33726440 PMCID:PMC7920525
• . 2021. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy 17(1):1-382. doi:10.1080/15548627.2020.1797280 PMID:33634751 PMCID:PMC4835977

2020

• Bartel S, Deshane J, Wilkinson T, Gabrielsson S. 2020. Extracellular Vesicles as Mediators of Cellular Cross Talk in the Lung Microenvironment. Front Med (Lausanne) 7:326. doi:10.3389/fmed.2020.00326 PMID:32850874 PMCID:PMC7417309
• Gafarov O, Watkins R, Fedorov V, Mirov S. 2020. Cross-section of electrical impact excitation in bulk n-type monocrystalline Al:Cr:ZnSe. Opt Mater Express 10:2135-2141. doi:10.1364/OME.402399
• Gupta N, Kozlovskaya V, Dolmat M, Yancey B, Oh J, Lungu C, Kharlampieva E. 2020. Photocatalytic nanocomposite microsponges of polylactide-titania for chemical remediation in water. ACS Appl. Polym. Mater 2(11):5188-5179. doi:10.1021/acsapm.0c00937
• Hiremath N, Young S, Ghossein H, Penumadu D, Vaidya U, Theodore M. 2020. Low cost textile-grade carbon-fiber epoxy composites for automotive and wind energy applications. Composites Part B: Engineering 198:108156. doi:10.1016/j.compositesb.2020.108156
• Hough KP, Curtiss ML, Blain TJ, Liu R, Trevor J, Deshane J, Thannickal V. 2020. Airway remodeling in asthma. Front Med (Lausanne) 7:191. doi:10.3389/fmed.2020.00191 PMID:32509793 PMCID:PMC7253669
• Hough KP, Deshane J. 2020. Cutting edge approaches for rapid characterization of airway exosomes. Methods 177:27-34. doi:10.1016/j.ymeth.2020.01.003 PMID:31953152 PMCID:PMC7198350
• Kooduvalli K, Vaidya U, Ozcan S. 2020. Life cycle assessment of compostable coffee pods: a US university based case study. Sci Rep 10:9158. doi:10.1038/s41598-020-65058-1 PMID:32513993 PMCID:PMC7280196
• Larson-Casey JL, Gu L, Fiehn O, Carter AB. 2020. Cadmium-mediated lung injury is exacerbated by the persistence of classically activated macrophages. J Biol Chem 295:15754-15766. doi:10.1074/jbc.RA120.013632 PMID:32917723 PMCID:PMC7667973
• Larson-Casey JL, He C, Che P, Wang M, Cai G, Kim Y, El Hamdaoui M, Grytz R, Dong Q, Carter AB. 2020. Technical advance: the use of tree shrews as a model of pulmonary fibrosis. PLoS One 15(11):e0241323. doi:10.1371/journal.pone.0241323 PMID:33141839 PMCID:PMC7608928
• Nam S, Fedorov V, Mirov S, Hong K. 2020. Octave-spanning mid-infrared femtosecond OPA in a ZnGeP2 pumped by a 2.4 mu m Cr:ZnSe chirped-pulse amplifier. Opt Express 28:32403-32414. doi:10.1364/OE.405648 PMID:33114927 PMCID:PMC7679192
• Pemmada R, Zhu X, Dash M, Zhou Y, Ramakrishna S, Peng X, Thomas V, Jain S, Nanda HS. 2020. Science-based strategies of antiviral coatings with viricidal properties for the COVID-19 like pandemics. Materials (Basel) 13:doi:10.3390/ma13184041 PMID:32933043 PMCID:PMC7558532
• Rana T, Jiang C, Liu G, Miyata T, Antony V, Thannickal V, Liu R. 2020. PAI-1 regulation of TGF-B1-induced alveolar type II cell senescence, SASP secretion, and SASP-mediated activation of alveolar macrophages. Am J Respir Cell Mol Biol 62:319-330. doi:10.1165/rcmb.2019-0071OC PMID:31513752 PMCID:PMC7055702
• Singh DK, Vaidya A, Thomas V, Theodore M, Kore S, Vaidya U. 2020. Finite element modeling of the fiber-matrix interface in polymer composites. Journal of Composites Science 4(2):58. doi:10.3390/jcs4020058
• Srivastava RK, Muzaffar S, Khan J, Traylor AM, Zmijewski J, Curtis L, George JF, Ahmad A, Antony V, Agarwal A, Athar M. 2020. Protective role of HO-1 against acute kidney injury caused by cutaneous exposure to arsenicals. Ann N Y Acad Sci 1480(1):155-169. doi:10.1111/nyas.14475 PMID:32885420 PMCID:PMC9109234
• Subbian S, Singh P, Kolloli A, Nemes E, Scriba T, Hanekom WA, Kaplan G. 2020. BCG vaccination of infants confers Mycobacterium tuberculosis strain-specific immune responses by leukocytes. ACS Infect Dis 6(12):3141-3146. doi:10.1021/acsinfecdis.0c00696 PMID:33226778
• Tsenova L, Fallows D, Kolloli A, Singh P, O'Brien P, Kushner N, Kaplan G, Subbian S. 2020. Inoculum size and traits of the infecting clinical strain define the protection level against Mycobacterium tuberculosis infection in a rabbit model. Eur J Immunol 50(6):858-872. doi:10.1002/eji.201948448 PMID:32130727
• Wang ML, Behrman P, Dulin A, Baskin ML, Buscemi J, Alcaraz KI, Goldstein CM, Carson TL, Shen M, Fitzgibbon M. 2020. Addressing inequities in COVID-19 morbidity and mortality: research and policy recommendations. Transl Behav Med 10:516-519. doi:10.1093/tbm/ibaa055 PMID:32542349 PMCID:PMC7337775

2019

• Larson-Casey JL, Vaid M, Gu L, He C, Cai G, Ding Q, Davis D, Berryhill TF, Wilson LS, Barnes S, Neighbors JD, Hohl RJ, Zimmerman KA, Yoder BK, Longhini AF, Hanumanthu VS, Surolia R, Antony V, Carter AB. 2019. Increased flux through the mevalonate pathway mediates fibrotic repair without injury. J Clin Invest 129:4962-4978. doi:10.1172/JCI127959 PMID:31609245 PMCID:PMC6819144
• Surolia R, Li FJ, Wang Z, Li H, Dsouza K, Thomas V, Mirov S, Perez-Sala D, Athar M, Thannickal V, Antony V. 2019. Vimentin intermediate filament assembly regulates fibroblast invasion in fibrogenic lung injury. JCI Insight 4:doi:10.1172/jci.insight.123253 PMID:30944258 PMCID:PMC6483650