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Program Publications: Yale University: Emerging Water Contaminants: Investigating and Mitigating Exposures and Health Risks

Superfund Research Program

Emerging Water Contaminants: Investigating and Mitigating Exposures and Health Risks

Center Director: Vasilis Vasiliou
Grant Number: P42ES033815
Funding Period: 2022-2027
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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  • Chen Y, Wang Y, Charkoftaki G, Orlicky DJ, Davidson EA, Wan F, Ginsberg GL, Thompson DC, Vasiliou V. 2022. Oxidative stress and genotoxicity in 1,4-doxane liver toxicity as evidence in a mouse model of glutathione deficiency. Sci Total Environ 806(Pt2):150703. doi:10.1016/j.scitotenv.2021.150703 PMID:34600989 PMCID:PMC8633123
  • Dornburg A, Mallik R, Wang Z, Bernal MA, Thompson B, Bruford EA, Nebert DW, Vasiliou V, Yohe LR, Yoder J, Townsend JP. 2022. Placing human gene families into their evolutionary context. Hum Genomics 16(1):56. doi:10.1186/s40246-022-00429-5 PMID:36369063 PMCID:PMC9652883
  • Ginsberg GL, Chen Y, Vasiliou V. 2022. Mechanistic considerations in 1,4-dioxane cancer risk assessment. Current Opinion in Environmental Science & Health 30:100407. doi:10.1016/j.coesh.2022.100407 PMID:37091947
  • Wang Y, Charkoftaki G, Davidson EA, Orlicky DJ, Tanguay RL, Thompson DC, Vasiliou V, Chen Y. 2022. Oxidative stress, glutathione, and CYP2E1 in 1,4-dioxane liver cytotoxicity and genotoxicity: insights from animal models. Current Opinion in Environmental Science & Health 29:100389. doi:10.1016/j.coesh.2022.100389
  • Zuccaro P, Thompson DC, de Boer J, Watterson A, Wang Q, Tang S, Shi X, Llompart M, Ratola N, Vasiliou V. 2022. Artificial turf and crumb rubber infill: an international policy review concerning the current state of regulations. Environ Chall 9:100620. doi:10.1016/j.envc.2022.100620 PMID:36644410 PMCID:PMC9838222


  • Charkoftaki G, Golla JP, Santos-Neto A, Orlicky DJ, Garcia-Milian R, Chen Y, Rattray NJ, Cai Y, Wang Y, Shearn CT, Mironova V, Wang Y, Johnson CH, Thompson DC, Vasiliou V. 2021. Identification of dose-dependent DNA damage and repair responses from subchronic exposure to 1,4-dioxane in mice using a systems analysis approach. Toxicol Sci 183(2):338-351. doi:10.1093/toxsci/kfab030 PMID:33693819 PMCID:PMC8921626


  • Godri Pollitt KJ, Kim J, Peccia JL, Elimelech M, Zhang Y, Charkoftaki G, Hodges B, Zucker I, Huang H, Deziel NC, Murphy K, Ishii M, Johnson CH, Boissevain A, O'Keefe E, Anastas P, Orlicky DJ, Thompson DC, Vasiliou V. 2019. 1,4-doxane as an emerging water contaminant: state of the science and evaluation of research needs. Sci Total Environ 690:853-866. doi:10.1016/j.scitotenv.2019.06.443 PMID:31302550
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