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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Project Publications: Boston University: Early Life Exposure to Tetrachloroethylene (PCE)-Contaminated Drinking Water and Social Stressors may Interact to Increase the Risk of Substance Use Later in Life

Superfund Research Program

Early Life Exposure to Tetrachloroethylene (PCE)-Contaminated Drinking Water and Social Stressors may Interact to Increase the Risk of Substance Use Later in Life

Project Leader: Ann Aschengrau
Co-Investigators: Lisa Gallagher, Richard Saitz, Renee Boynton-Jarrett
Grant Number: P42ES007381
Funding Period: 2000-2021

Project-Specific Links

Publications

2023

2020

  • Aschengrau A, Grippo A, Winter MR, Shea M, White RF, Saitz R. 2020. Drug use disorder following early life exposure to tetrachloroethylene (PCE)-contaminated drinking water: a retrospective cohort study. Environmental Health 19:99. doi:10.1186/s12940-020-00638-2 PMID:32943075 PMCID:PMC7495895
  • Aschengrau A, Winter MR, Gallagher L, Vieira VM, Butler L, Fabian MP, Carwile JL, Wesselink AK, Mahalingaiah S, Janulewicz PA, Weinberg JM, Webster TF, Ozonoff DM. 2020. Reproductive and developmental health effects of prenatal exposure to tetrachloroethylene-contaminated drinking water. Environ Sci Process Impacts 22:555-566. doi:10.1039/c9em00590k PMID:32051987

2019

2018

  • Aschengrau A, Gallagher L, Winter MR, Butler L, Patricia FM, Vieira VM. 2018. Modeled exposure to tetrachloroethylene-contaminated drinking water and the risk of placenta-related stillbirths. Environ Health 17:58. doi:10.1186/s12940-018-0402-1 PMID:29970097 PMCID:PMC6029409
  • Aschengrau A, Gallagher LG, Winter MR, Butler L, Fabian MP, Vieira VM. 2018. Modeled exposure to tetrachloroethylene-contaminated drinking water and the occurrence of birth defects: a case-control study from Massachusetts and Rhode Island. Environ Health 17(1):75. doi:10.1186/s12940-018-0419-5 PMID:30400949 PMCID:PMC6219161
  • Wesselink AK, Hatch EE, Wise L, Rothman KJ, Vieira VM, Aschengrau A. 2018. Exposure to tetrachloroethylene-contaminated drinking water and time to pregnancy. Environ Res 167:136-143. doi:10.1016/j.envres.2018.07.012 PMID:30014895

2017

  • Butler L, Janulewicz PA, Carwile JL, White RF, Winter MR, Aschengrau A. 2017. Childhood and adolescent fish consumption and adult neuropsychological performance: An analysis from the Cape Cod Health Study. Neurotoxicol Teratol 61:47-57. doi:10.1016/j.ntt.2017.03.001 PMID:28263856
  • Gallagher LG, Webster TF, Aschengrau A. 2017. Exploring associations between prenatal solvent exposures and teenage drug and alcohol use: a retrospective cohort study. Environ Health 16(1):26. doi:10.1186/s12940-017-0232-6 PMID:28283038 PMCID:PMC5346200
  • Wesselink AK, Carwile JL, Fabian MP, Winter MR, Butler L, Mahalingaiah S, Aschengrau A. 2017. Residential proximity to roadways and ischemic placental disease in the Cape Cod Family Health Study. Int J Environ Res Public Health 14:682. doi:10.3390/ijerph14070682 PMID:28672786 PMCID:PMC5551120

2016

  • Aschengrau A, Gallagher LG, Winter MR, Vieira VM, Webster TF, Janulewicz PA, Ozonoff DM. 2016. No association between unintentional head injuries and early-life exposure to tetrachloroethylene (PCE)-contaminated drinking water. J Occup Environ Med 58(10):1040-1045. doi:10.1097/JOM.0000000000000850 PMID:27513173 PMCID:PMC5704661
  • Aschengrau A, Janulewicz PA, White RF, Vieira VM, Gallagher LG, Getz KD, Webster TF, Ozonoff DM. 2016. Long-term neurotoxic effects of early-life exposure to tetrachloroethylene-contaminated drinking water. Ann Glob Health 82(1):169-179. doi:10.1016/j.aogh.2016.01.013 PMID:27325074 PMCID:PMC4916338
  • Carwile JL, Butler L, Janulewicz PA, Winter MR, Aschengrau A. 2016. Childhood fish consumption and learning and behavioral disorders. Int J Environ Res Public Health 13(11):doi:10.3390/ijerph13111069 PMID:27827868 PMCID:PMC5129279
  • Hewlett MM, Chow E, Aschengrau A, Mahalingaiah S. 2016. Prenatal exposure to endocrine disruptors: a developmental etiology for polycystic ovary syndrome. Reprod Sci 24(1):19-27. doi:10.1177/1933719116654992 PMID:27342273
  • Mahalingaiah S, Hart JE, Laden F, Farland LV, Hewlett MM, Chavarro J, Aschengrau A, Missmer SA. 2016. Adult air pollution exposure and risk of infertility in the Nurses' Health Study II. Hum Reprod 31(3):638-647. doi:10.1093/humrep/dev330 PMID:26724803 PMCID:PMC4755443
  • Mahalingaiah S, Winter MR, Aschengrau A. 2016. Association of prenatal and early life exposure to tetrachloroethylene (PCE) with polycystic ovary syndrome and other reproductive disorders in the cape cod health study: A retrospective cohort study. Reprod Toxicol 65:87-94. doi:10.1016/j.reprotox.2016.07.005 PMID:27412368 PMCID:PMC5091798

2015

  • Aschengrau A, Winter MR, Vieira VM, Webster TF, Janulewicz PA, Gallagher LG, Weinberg JM, Ozonoff DM. 2015. Long-term health effects of early life exposure to tetrachloroethylene (PCE)-contaminated drinking water: a retrospective cohort study. Environ Health 14:36. doi:10.1186/s12940-015-0021-z PMID:25889838 PMCID:PMC4397674
  • Hoffman K, Aschengrau A, Webster TF, Bartell SM, Vieira VM. 2015. Associations between residence at birth and mental health disorders: a spatial analysis of retrospective cohort data. BMC Public Health 15:688. doi:10.1186/s12889-015-2011-z PMID:26195105 PMCID:PMC4508761

2014

2013

  • Janulewicz PA, Killiany RJ, White RF, Martin BR, Winter MR, Weinberg JM, Aschengrau A. 2013. Structural Magnetic Resonance Imaging in an adult cohort following prenatal and early postnatal exposure to tetrachloroethylene (PCE)-contaminated drinking water. Neurotoxicol Teratol 38:13-20. doi:10.1016/j.ntt.2013.03.060 PMID:23571160 PMCID:PMC3893699

2012

  • Getz KD, Janulewicz PA, Rowe S, Weinberg JM, Winter MR, Martin BR, Vieira VM, White RF, Aschengrau A. 2012. Prenatal and early childhood exposure to tetrachloroethylene and adult vision. Environ Health Perspect doi:10.1289/ehp.1103996 PMID:22784657 PMCID:PMC3440105
  • Janulewicz PA, White RF, Martin BR, Winter MR, Weinberg JM, Vieira VM, Aschengrau A. 2012. Adult neuropsychological performance following prenatal and early postnatal exposure to tetrachloroethylene (PCE)-contaminated drinking water. Neurotoxicol Teratol 34(3):350–359. doi:10.1016/j.ntt.2012.04.001 PMID:22522125 PMCID:PMC3553661

2010

2008

  • Aschengrau A, Gallagher LG, Webster TF, Heeren T, Ozonoff DM, Spence LA. 2008. Evaluation of the Webler-Brown model for estimating tetrachloroethylene exposure from vinyl-lined asbestos-cement pipes. Environ Health 7:24. doi:10.1186/1476-069X-7-24 PMID:18518975 PMCID:PMC2432054
  • Aschengrau A, Weinberg JM, Rogers S, Gallagher LG, Winter MR, Vieira VM, Webster TF, Ozonoff DM. 2008. Prenatal exposure to tetrachloroethylene-contaminated drinking water and the risk of adverse birth outcomes. Environ Health Perspect 116(6):814-820. doi:10.1289/ehp.10414 PMID:18560539 PMCID:PMC2430239
  • Janulewicz PA, White RF, Winter MR, Weinberg JM, Gallagher LG, Vieira VM, Webster TF, Aschengrau A. 2008. Risk of learning and behavioral disorders following prenatal and early postnatal exposure to tetrachloroethylene (PCE)-contaminated drinking water. Neurotoxicol Teratol 30(3):175-185. doi:10.1016/j.ntt.2008.01.007 PMID:18353612 PMCID:PMC2494864
  • Vieira VM, Webster TF, Weinberg JM, Aschengrau A. 2008. Spatial-temporal analysis of breast cancer in upper Cape Cod, Massachusetts. Int J Health Geogr 7:46. doi:10.1186/1476-072X-7-46 PMID:18700963 PMCID:PMC2538515
  • Webster TF, Hoffman K, Weinberg JM, Vieira VM, Aschengrau A. 2008. Community- and individual-level socioeconomic status and breast cancer risk: multilevel modeling on Cape Cod, Massachusetts. Environ Health Perspect 116(8):1125-1129. doi:10.1289/ehp.10818 PMID:18709175 PMCID:PMC2516595

2006

2005

  • Vieira VM, Aschengrau A, Ozonoff DM. 2005. Impact of tetrachloroethylene-contaminated drinking water on the risk of breast cancer: using a dose model to assess exposure in a case-control study. Environ Health 4(1):3. doi:10.1186/1476-069X-4-3 PMID:15733317 PMCID:PMC554766

2004

  • Brody JG, Aschengrau A, McKelvey W, Rudel RA, Swartz CH, Kennedy T. 2004. Breast cancer risk and historical exposure to pesticides from wide-area applications assessed with GIS. Environ Health Perspect 112(8):889-897. PMID:15175178

2003

  • Aschengrau A, Rogers S, Ozonoff DM. 2003. Perchloroethylene-contaminated drinking water and the risk of breast cancer: additional results from Cape Cod, Massachusetts, USA. Environ Health Perspect 111(2):167-173. PMID:12573900

2002

  • Lash TL, Aschengrau A. 2002. A null association between active or passive cigarette smoking and breast cancer risk. Breast Cancer Res Treat 75(2):181-184. PMID:12243511
  • Paulu C, Aschengrau A, Ozonoff DM. 2002. Exploring associations between residential location and breast cancer incidence in a case-control study. Environ Health Perspect 110(5):471-478. PMID:12003750

2001

  • Morabia A, Lash TL, Aschengrau A. 2001. Passive cigarette smoking and breast cancer. In: Environmental tobacco smoke: toxicity, treatment and prevention. CRC Press, Boca Raton, FL.
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