Research Briefs: Dartmouth College

Superfund Research Program

Sources and Protracted Effects of Early Life Exposure to Arsenic and Mercury

Center Director: Celia Y. Chen
Grant Number: P42ES007373
Funding Period: 1995-2021

Research Briefs

• 254 - Low-Dose Organic Arsenic Exposure Negatively Affects the Immune System in the Lung -- Stanton
  Release Date: 02/03/2016

  Arsenic exposure may alter immune response to a common pathogen in the lung, according to a recent study from the Dartmouth College Superfund Research Program (SRP) Center. This study provides insight into how arsenic exposure may increase the risk of respiratory infection and chronic obstructive pulmonary disease, which is associated with chronic bacterial infections and other non-malignant lung infections. The study also helps discern the contribution of organic forms of arsenic alone to the alteration of the innate immune response in the lung.

• 246 - River Algae Affects Mercury Pollution at Superfund Site -- Chen
  Release Date: 06/03/2015

  A new study has shown that periphyton -- a community of algae, bacteria, and other natural material living on submerged surfaces -- is helping to transform mercury from a Superfund site into methylmercury, a more toxic form. The study, led by Dartmouth College Superfund Research Program (SRP) researchers, also found lower than anticipated levels of methylmercury in small fish located downstream from a former chemical plant, despite elevated levels of methylmercury in sediment, water, and periphyton.

• 218 - Marine Mercury: From Sources to Seafood -- Chen, Rardin
  Release Date: 02/06/2013

  Mercury released into the air and then deposited into oceans contaminates seafood commonly eaten by people in the U.S. and globally, according to findings from the Coastal and Marine Mercury Ecosystem Research Collaborative (C-MERC).

• 208 - A Flurry of Arsenic Findings -- Ahsan, Jackson, Lu
  Release Date: 04/04/2012

  New evidence about arsenic abounds in SRP studies published recently. The studies reveal that food is an unexpected source of arsenic exposure, demonstrate adverse health effects are from low levels of exposure, show the mechanisms behind some of arsenic's health effects, and suggest a strategy for reducing exposure from well water.

• 176 - A New Analytical Method to Support Studies of Mercury Bioavailability/Bioaccumulation in Aquatic Ecosystems -- Taylor, Chen, Jackson
  Release Date: 08/05/2009
  
  
• 173 - Are There Links Between Selenium Intake and Bladder Cancer? -- Karagas
  Release Date: 05/06/2009
  
  
• 151 - The Dartmouth Community Outreach Core Facilitates Change in New Hampshire Lead Laws -- Serrell, Fleishman
  Release Date: 07/03/2007
  
  
• 145 - Arsenic Affects All Five Steroid Receptors -- Hamilton
  Release Date: 01/03/2007
  
  
• 144 - A Comparative Toxicology Study of Metal Mixtures -- Folt, Chen
  Release Date: 12/06/2006
  
  
• 128 - Identifying Predictors of Mercury Burdens in Fish -- Folt, Chen
  Release Date: 08/02/2005
  
  
• 89 - Clues to Methylmercury Levels in Freshwater Fish -- Folt
  Release Date: 05/01/2002
  
  
• 76 - Low Dose Arsenic Exposures Related to Skin Cancer -- Karagas
  Release Date: 04/04/2001
  
  
• 30 - Understanding the Molecular Basis for Metal-Induced Cancers -- Hamilton
  Release Date: 09/30/1998
  
  
• 23 - Bioaccumulation and Biomagnification of Metals in Lakes -- Folt
  Release Date: 06/24/1998
  
  
• 3 - Low Levels of Arsenite Found to Decrease Hepatic Cytochrome P450 Activity -- Sinclair
  Release Date: 09/03/1997