Superfund Research Program
Multiscale Imaging and Proteomics Core
Project Leader: Mark H. Ellisman
Co-Investigators: Elizabeth A. Komives, Roger Y. Tsien
Grant Number: P42ES010337
Funding Period: 2005-2017
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Title: Gene expression profile of WT and TAK1 KO livers
Accession Number: E-GEOD-51962
Link to Dataset: http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-51962/
Repository: ArrayExpress
Data Type(s): Gene Expression
Experiment Type(s): Transcription profiling by array
Organism(s): Mus musculus
Summary: The effect of ablation of Tak1 gene in the liver was characterized. RNA was extracted from 1-month-old WT and hepatocyte specific TAK1-deleted mice
Publication(s) associated with this dataset:- Inokuchi-Shimizu S, Park E, Roh Y, Yang L, Zhang B, Song J, Liang S, Pimienta M, Taniguchi K, Wu X, Asahina K, Lagakos W, Mackey MR, Akira S, Ellisman MH, Sears DD, Olefsky J, Karin M, Brenner DA, Seki E. 2014. TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis. J Clin Invest 124(8):3566-3578. doi:10.1172/JCI74068 PMID:24983318 PMCID:PMC4109552