Superfund Research Program
Comprehensive Tools and Models for Addressing Exposure to Mixtures During Environmental Emergency-Related Contamination Events
Center Director: Ivan Rusyn
Grant Number: P42ES027704
Funding Period: 2017-2027
Program Links
Title: Expression profiles of HepG2 cells treated with low-, high-dose of acetaminophen and solvent control
Accession Number: GSE53216
Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE53216
Repository: Gene Expression Omnibus (GEO)
Data Type(s): Gene Expression
Experiment Type(s): Expression profiling by array
Organism(s): Homo sapiens
Summary: The transcriptomics changes induced in the human liver cell line HepG2 by low and high doses of acetaminophen and solvent controls after treatment for 4 time points (12h, 24h, 48h and 72h)
Publication(s) associated with this dataset:- House JS, Bouzos E, Fahy K, Francisco VM, Lloyd D, Wright FA, Motsinger-Reif A, Asuri P, Wheeler K. 2020. Low dose silver nanoparticle surface chemistry and temporal effects on gene expression in human liver cells. Wiley Interdiscip Rev Nanomed Nanobiotechnol doi:10.1002/smll.202000299 PMID:32227433 PMCID:PMC7446734