Superfund Research Program
Arsenic-Obesity-Diabetes Interactions
Project Leader: Fernando Pardo-Manuel de Villena
Co-Investigators: Miroslav Styblo, Rebecca C. Fry, Fei Zou
Grant Number: P42ES031007
Funding Period: 2020-2025
Project-Specific Links
- Project Summary
Title: Dissecting the Genetic Architecture of Renal Function and the biomarker Cystatin C in Aging
Accession Number: GSE122061
Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE122061
Repository: Gene Expression Omnibus (GEO)
Data Type(s): Gene Expression
Experiment Type(s): Expression profiling by array
Organism(s): Mus musculus
Summary: In this study, we utilized 95 Diversity Outbred (DO) female mice, 56 weeks of age, to perform eQTL analysis of renal biomarkers in blood and urine. We also determined the correlation between kidney biomarkers and expression levels of the genes in kidney.
Publication(s) associated with this dataset:- Huda M, VerHague M, Albright J, Smallwood T, Bell TA, Que E, Miller DR, Roshanravan B, Allayee H, Pardo-Manuel de Villena F, Bennett BJ. 2020. Dissecting the Genetic Architecture of Cystatin C in Diversity Outbred Mice. G3 7:2529-2541. doi:10.1534/g3.120.401275 PMID:32467129