Superfund Research Program
MIT Superfund Hazardous Substance Basic Research Program
Center Director: William G. Thilly
Grant Number: P42ES004675
Funding Period: 1987-2000
- Projects and Cores
News Items List
Tool quantifies differences in DNA repair among individuals
Paper of the Month - November 2021
CometChip -- a high-throughput tool developed with NIEHS funds to quantify DNA damage -- can be used to measure differences among individuals in terms of their bodies capacity to repair such damage, according to a recent institute-supported study. That information may help to shed light on how much of a person s disease risk is due to genetic versus environmental factors.
Scientific art competition showcases trainees' research, imagination
Environmental Factor - September 2021
When the COVID-19 pandemic forced university laboratories to shut down or go remote, the NIEHS Superfund Research Program (SRP) created an opportunity for trainees to celebrate their research efforts and the stories behind them. Led by SRP Health Scientist Administrator Danielle Carlin, Ph.D., SRP hosted a scientific art competition for trainees.
DNA repair enzyme controls switch from cancer to tissue damage
Paper of the Month - June 2021
NIEHS-funded researchers discovered a DNA-repair molecule that affects susceptibility to disease in mice exposed to N-nitrosodimethylamine (NDMA). Alkyladenine DNA glycosylase (AAG) is known to be an important player in DNA repair, but this study revealed for the first time that too much or too little can control the switch between cancer and lethality.
Linking a DNA Repair Enzyme to Cancer Susceptibility
SRP News Page - May 2021
Researchers at the Massachusetts Institute of Technology (MIT) NIEHS Superfund Research Program (SRP) Center uncovered a mechanism that may explain how N-Nitrosodimethylamine (NDMA) can lead to DNA damage and cancer in mice.
Superfund Wetterhahn Award goes to Jennifer Kay
Environmental Factor - January 2021
Now at Silent Spring Institute, the former MIT scientist is dedicated to research, science literacy, and social justice.
K.C. Donnelly Externships awarded to outstanding Superfund trainees
Environmental Factor - August 2020
Eleven outstanding trainees in the NIEHS Superfund Research Program (SRP) have won K.C. Donnelly Externship Award Supplements. The annual awards allow trainees to work side-by-side with experts at an outside institution to learn new methods and techniques to enrich their research.