Superfund Research Program

Effects-Related Biomarkers of Environmental Neurotoxic Exposures

Center Director: Evan P. Gallagher
Grant Number: P42ES004696
Funding Period: 1987-2023

Program Links

News Items List

• SRP Highlighted at SOT
  SRP News Page - April 2023
  NIEHS Superfund Research Program (SRP)-funded scientists from across the country gathered in person for the 2023 Society of Toxicology (SOT) Annual Meeting to share their research and exchange ideas. Held March 19 - 23 in Nashville, Tennessee, the 62nd SOT meeting and ToxExpo drew more than 5,000 attendees who gave more than 2,000 presentations and participated in more than 70 sessions.
  

• SRP Shines at SOT
  SRP News Page - April 2022
  NIEHS Superfund Research Program (SRP) grantees from across the country gathered in person and virtually for the 2022 Society of Toxicology (SOT) Annual Meeting, held March 27-31 in San Diego. The meeting highlighted cutting-edge research.
  

• Extramural Paper of the Month: Changes in Gut, Liver may Contribute to Alzheimer’s Disease Susceptibility
  Paper of the Month - March 2022
  Researchers at the University of Washington SRP Center determined how changes in the gut and liver may contribute to cadmium-induced Alzheimer’s disease (AD).
  

• Changes in gut, liver may contribute to Alzheimers disease susceptibility
  Paper of the Month - March 2022
  NIEHS-funded researchers determined how changes in the gut and liver may contribute to cadmium-induced Alzheimers disease (AD). They previously showed that male mice with a genetic variant called apolipoprotein E4 (ApoE4), a known risk factor for AD, were most susceptible to the disease following cadmium exposure. Here, they shed light on how cadmium and ApoE4 alter the gut and liver in ways that may promote AD.
  

• Scientists design risk communication strategies to improve health
  Environmental Factor - November 2021
  At NIEHS Superfund Research Program event, hundreds learned about tailoring public messages related to environmental risk.
  

• Ongoing Duwamish River recovery inspires video series, book
  Environmental Factor - August 2020
  A century ago, engineers and city planners straightened and deepened the Duwamish River to create an industrial center for the young city of Seattle. As the city grew, the waterway became contaminated with sewage, toxic chemicals, and storm water runoff. In 2001, the river was listed as a Superfund site. Now, the University of Washington (UW) Superfund Research Program (SRP) is promoting a new video series and a book, released July 11, to educate people about this important waterway.
  

• K.C. Donnelly Externships awarded to outstanding Superfund trainees
  Environmental Factor - August 2020
  Eleven outstanding trainees in the NIEHS Superfund Research Program (SRP) have won K.C. Donnelly Externship Award Supplements. The annual awards allow trainees to work side-by-side with experts at an outside institution to learn new methods and techniques to enrich their research.
  

• Cadmium Exposure Impairs Production of Neurons Responsible for Learning and Memory
  Research Brief - January 2020
  A new study funded by the Superfund Research Program (SRP) shows cadmium exposure can impair new neurons from forming and maturing in the hippocampus region of the brain. Led by Zhengui Xia, Ph.D., the researchers at the University of Washington (UW) SRP Center also found that cadmium can lead to the death of stem cells that produce these neurons. In people, learning and memory formation depends on the production of new neurons in this region of the brain.
  

• River tour during SRP meeting spotlights local perspectives
  Environmental Factor - January 2020
  On the last day of the 2019 NIEHS Superfund Research Program (SRP) Annual Meeting, held Nov. 18-20 in Seattle, participants were offered a boat tour of the Duwamish River. Organized by meeting hosts from the University of Washington (UW) SRP Center, the tour spotlighted the history of the Lower Duwamish Waterway Superfund Site and the community groups that have worked to protect the river as a cultural resource.
  

• New houseplant enhances cleanup of air in homes
  Paper of the Month - February 2019
  Scientists previously funded by NIEHS developed a houseplant that can remove chloroform and benzene from the air around it. Benzene in the home can originate from outside air, fuel storage in attached garages, and tobacco smoke. Chloroform can be released into the air in small amounts from water during showering.