Superfund Research Program
Environmental PPARγ Pathway Activators: Multifaceted Metabolic Disruptors Impacting Adipose and Bone Homeostasis
News Items List
New Model to Examine PFAS Sheds Light on Lipid Disruption Mechanisms
Research Brief - January 2021
Researchers from the Boston University (BU) Superfund Research Program (SRP) Center developed a novel study design that generated new insight on the effects of perfluorooctanoic acid (PFOA) on cholesterol regulation in the liver. Led by Jennifer Schlezinger, Ph.D., the team also investigated the effects of PFOA on the human peroxisome proliferator activated receptor alpha (hPPARa), a transcription factor that regulates lipid homeostasis.
Superfund Wetterhahn Award goes to Stephanie Kim
Environmental Factor - December 2018
The NIEHS Superfund Research Program (SRP) announced Stephanie Kim of Boston University (BU) as the 21st recipient of the annual Karen Wetterhahn Memorial Award. The announcement was made Nov. 29, during the SRP Annual Meeting in Sacramento, California.
TBT Alters Bone Marrow Microenvironment and Suppresses Important Immune Cells
Research Brief - August 2017
Researchers at the Boston University Superfund Research Program (BU SRP) Center reported that tributyltin (TBT) may promote aging-related problems in immune health. The team, led by Jennifer Schlezinger, Ph.D., found that TBT impacts bone marrow B cells directly by triggering cell death and indirectly by changing the microenvironment of bone marrow vital for supporting immune health.
The Flame Retardant Firemaster 550, Fat Cells, and Bone Health
Research Brief - September 2014
Researchers from the Boston University (BU) and Duke University Superfund Research Program (SRP) Centers found that components of the flame-retardant mixture Firemaster® 550 (FM550) may stimulate growth of fat cells and reduce bone health.