Superfund Research Program

Bioinformatics and Molecular Modeling Core

Project Leader: Stefano Monti
Co-Investigator: Sandor Vajda
Grant Number: P42ES007381
Funding Period: 2000-2021

Project-Specific Links

News Items List

• Chemicals alter fat cells, disrupt healthy metabolism
  Environmental Factor - November 2019
  Chemicals can work differently through the same biological receptor to generate different types of fat cells and disrupt healthy metabolic functions, according to Stephanie Kim, Ph.D., in an Oct. 21 lecture at NIEHS.
  

• New Method Quickly Screens Chemicals for Cancer Risk
  Research Brief - June 2019
  Boston University (BU) researchers, in collaboration with researchers at the National Toxicology Program (NTP) and the Broad Institute, have developed and evaluated a new approach to assess whether exposure to a chemical increases a person's long-term cancer risk. The fast, cost-effective method uses gene expression profiling, which measures the activity of a thousand or more genes to capture what is happening in a cell. Based on gene expression profiling data, the researchers were able to infer specific biological changes at the cellular level and predict potential carcinogenicity of chemicals, or the ability of chemicals to cause cancer.