Superfund Research Program
Oxidative Stress Core
Project Leader: Tammy R. Dugas
Grant Number: P42ES013648
Funding Period: 2011-2018
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News Items List
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Study Sheds Light on Respiratory Toxicity of EPFRs
Research Brief - January 2019
A new SRP study explains how particulate matter (PM) containing environmentally persistent free radicals (EPFRs) activate the aryl hydrocarbon receptor (AhR). AhR is known to play an important role in detecting and responding to a variety of pollutants. These findings could prove useful in understanding the underlying mechanism of diseases known to be associated with inhalation of PM, such as cardiovascular disease.