Superfund Research Program
Predicting the Toxicity of Complex PAH Mixtures
News Items List
Connection between genes, response to environmental chemicals
Paper of the Month - September 2018
NIEHS grantees developed a new method to identify individual-level genetic variation in response to chemical exposures. The approach, which linked zebrafish studies and bioinformatic approaches, might help identify new genetic factors that explain differences in chemical sensitivity.
Using Zebrafish for Chemical Screening and Sustainable Chemical Design
SRP News Page - January 2017
A recent review out of the Oregon State University Superfund Research Program (OSU SRP) describes how zebrafish have become an important model to screen for chemical toxicity. The article, published in the journal Green Chemistry, points to major advances in testing methods that have positioned zebrafish as an applicable model for chemical safety evaluations and efforts to develop more sustainable chemicals.
High-throughput Screening Examines Multiple Effects of 1060 Compounds on Zebrafish
SRP News Page - February 2014
An investigation led by Oregon State University Superfund Research Program grantee Robert Tanguay, Ph.D., used high-throughput screening to analyze 1,060 unique compounds for 22 possible effects on zebrafish embryos.