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Your Environment. Your Health.

Final Progress Reports: University of Kentucky: Synthesis

Superfund Research Program

Synthesis

Project Leader: Larry W. Robertson (University of Iowa)
Grant Number: P42ES007380
Funding Period: 2000 - 2005

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Final Progress Reports

Year:   2004 

This Core is responsible for synthesizing, purifying and characterizing all PCBs and PCB metabolites required for the research outlined in the research projects of this SBRP grant.  PCBs and PCB metabolites continue to be provided by Dr. Robertson’s group, which relocated to the University of Iowa.  Under the oversight of Dr. Arthur Cammers, the core also synthesized high-purity PCBs at the University of Kentucky, and batches of PCB 77 synthesized at both Universities of Iowa and Kentucky were studied and compared in biological experiments in Dr. Hennig’s laboratory.  Thus, they successfully demonstrated synthesis, purification and characterization of PCBs provided by Dr. Cammers.  Special needs of PCBs or their metabolites continue to be met thought synthesis activities and a subcontract with the University of Iowa.  At the University of Kentucky, the current focus of synthesis continues to be on vitamin B12 analogues or corrin derivatives needed for specific projects.

 

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