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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Final Progress Reports: University of California-San Diego: Mouse Molecular Genetics Core

Superfund Research Program

Mouse Molecular Genetics Core

Project Leader: Pamela L. Mellon
Grant Number: P42ES010337
Funding Period: 2000-2017
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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Final Progress Reports

Year:   2016  2009  2004 

The Mouse Molecular Genetics Core has advanced services for the UCSD Superfund Program in 2016. The research team has improved their success with creating mice using the CRISPR directed mutagenesis system. This method allows direct mutation of genes in the mouse genome, the creation of internal deletions, and insertion of tags or other small sequences. This frequently utilized service is more efficient and flexible. Furthermore, many of the mouse models created for our Superfund investigators are being utilized widely throughout the national Superfund program for studies of toxicology and biomedical problems pertaining to Superfund chemicals.

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