Superfund Research Program
Adverse Human Health Impacts of Nanomaterials
Project Leader: Agnes B. Kane
Grant Number: P42ES013660
Funding Period: 2009-2021
The Adverse Human Health Impacts of Nanomaterials Project and the Nanomaterial Design for Environmental Health and Safety Project developed a framework for early screening of 2D, sheet-like nanomaterials for potential toxicity. This framework incorporates dissolution kinetic studies in simulated biologically-relevant fluids and characterization of dissolution products using measurement of dissolved species and in vitro toxicity testing. This framework was applied to molybdenum trioxide nanoribbons during the past year and published in Gray et al., Environmental Science Nano 5: 2545-2559, 2018. This paper was selected by the editor as one of the top 10 percent of papers published in this journal.