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Your Environment. Your Health.

Project Publications: University of California-Davis: Integrated Response to Toxic Perturbation

Superfund Research Program

Integrated Response to Toxic Perturbation

Project Leader: Robert H. Rice
Co-Investigators: Alan R. Buckpitt, J. Bruce German, Dietmar Kültz
Grant Number: P42ES004699
Funding Period: 2000-2010

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  • Kumar V, Bouameur J, Bar J, Rice RH, Hornig-Do H, Roop DR, Schwarz N, Brodesser S, Thiering S, Leube RE, Wiesner RJ, Vijayaraj P, Brazel CB, Heller S, Binder H, Loffler-Wirth H, Seibel P, Magin TM. 2015. A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol 211(5):1057-1075. doi:10.1083/jcb.201404147 PMID:26644517 PMCID:PMC4674273


  • Kim H, Majkova Z, Dechant JE, Gee SJ, Tabares-da Rosa S, Gonzalez-Sapienza GG, Hammock BD, McCoy MR. 2012. Isolation of alpaca anti-hapten heavy chain single domain antibodies for development of sensitive immunoassay. Anal Chem 84(2):1165-1171. doi:10.1021/ac2030255 PMID:22148739 PMCID:PMC3264785


  • Barile D, Marotta M, Chu CR, Mehra R, Grimm R, Lebrilla CB, German JB. 2010. Neutral and acidic oligosaccharides in Holstein-Friesian colostrum during the first 3 days of lactation measured by high performance liquid chromatography on a microfluidic chip and time-of-flight mass spectrometry. J Dairy Sci 93(9):3940-3949. doi:10.3168/jds.2010-3156 PMID:20723667 PMCID:PMC3951277


  • Barbosa-Sicard E, Popp R, Fisslthaler B, Hammock BD, Falck JR, Busse R, Fleming I, Keseru B, Dietrich A, Gudermann T, Weissmann N. 2008. Epoxyeicosatrienoic acids and the soluble epoxide hydrolase are determinants of pulmonary artery pressure and the acute hypoxic pulmonary vasoconstrictor response. FASEB J 22(12):4306-4315. doi:10.1096/fj.08-112821 PMID:18725458 PMCID:PMC2614611
  • Shearer GC, Newman JW. 2008. Lipoprotein lipase releases esterified oxylipins from very low-density lipoproteins. Prostaglandins Leukot Essent Fatty Acids 79(6):215-222. doi:10.1016/j.plefa.2008.09.023 PMID:19042114 PMCID:PMC2629508


  • German JB, Lemay DG, Zivkovic AM. 2007. Building the bridges to bioinformatics in nutrition research. Am J Clin Nutr 86(5):1261-1269. PMID:17991634
  • Kültz D, Fiol D, Valkova N, Gomez-Jimenez S, Chan SY, Lee JV. 2007. Functional genomics and proteomics of the cellular osmotic stress response in 'non-model' organisms. J Exp Biol 210(Pt9):1593-1601. doi:10.1242/jeb.000141 PMID:17449824
  • Ngo MA, Sinitsyna NN, Qin Q, Rice RH. 2007. Oxygen-dependent differentiation of human keratinocytes. Journal of Investigative Dermatology 127(2):354-61. PMID:16977326
  • Park E, Mak SK, Kültz D, Hammock BD. 2007. Determination of cytotoxicity of nephrotoxins on murine and human kidney cell lines. J Environ Sci Health B 43:71-74. PMID:18161576


  • Perroud B, Lee J, Valkova N, Dhirapong A, Lin P, Fiehn O, Kültz D, Weiss RH. 2006. Pathway analysis of kidney cancer using proteomics and metabolic profiling. Mol Cancer 5:64. PMID:17123452
  • Rea MA, Zhou L, Qin Q, Barrandon Y, Easley KW, Gungner SF, Phillips MA, Holland WS, Gumerlock PH, Rocke DM, Rice RH. 2006. Spontaneous immortalization of human epidermal cells with naturally elevated telomerase. Journal of Investigative Dermatology 126(11):2507-15. PMID:16778798


  • Lee C, Lee YM, Rice RH. 2005. Human epidermal cell protein responses to arsenite treatment in culture. Chem Biol Interact 155(1-2):43-54. PMID:15899475
  • Wheelock AM, Buckpitt AR. 2005. Software-induced variance in two-dimensional gel electrophoresis image analysis. Electrophoresis 26:4508-4520. PMID:16315176


  • Chen Y, Zhao Y, Kalaslavadi TB, Hamati E, Nehrke K, Le AD, Ann DK, Wu R. 2004. Genome-wide search and identification of a novel gel-forming mucin MUC19/Muc19 in glandular tissues. Am J Respir Cell Mol Biol 30(2):155-165. doi:10.1165/rcmb.2003-0103OC PMID:12882755
  • Shultz MA, Zhang L, Gu Y, Baker GL, Fanucchi MV, Padua AM, Gurske WA, Morin D, Penn SG, Jovanovich SB, Plopper CG, Buckpitt AR. 2004. Gene expression analysis in response to lung toxicants: I Sequencing and microarray development. Am J Respir Cell Mol Biol 30(3):296-310. doi:10.1165/rcmb.2003-0214OC PMID:12947022


  • Chen Y, Thai P, Zhao Y, Ho Y, DeSouza MM, Wu R. 2003. Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop. Biol Chem 278(19):17036-17043. PMID:12624114
  • Kao CY, Chen Y, Zhao Y, Wu R. 2003. ORFeome-based search of airway epithelial cell-specific novel human [beta]-defensin genes. Am J Respir Cell Mol Biol 29(1):71-80. PMID:12600824
  • Yoneda K, Chang MM, Chmiel K, Chen Y, Wu R. 2003. Application of high-density DNA microarray to study smoke- and hydrogen peroxide-induced injury and repair in human bronchial epithelial cells. J Am Soc Nephrol 14(Suppl.3):S284-S289. PMID:12874447


  • Buckpitt AR, Boland BC, Isbell MA, Morin D, Shultz MA, Baldwin RM, Chan K, Karlsson A, Lin C, Taff A, West JA, Fanucchi MV, Van Winkle LS, Plopper CG. 2002. Naphthalene-induced respiratory tract toxicity: metabolic mechanisms of toxicity. J Mol Biol 34(4):791-820. PMID:12487150
  • Chang W, Reddy SP, Di YP, Yoneda K, Harper R, Wu R. 2002. Regulation of thioredoxin gene expression by vitamin A in human airway epithelial cells. Am J Respir Cell Mol Biol 26(5):627-635. doi:10.1165/ajrcmb.26.5.4276 PMID:11970916
  • Krig SR, Chandraratna RA, Chang MM, Wu R, Rice RH. 2002. Gene-specific TCDD suppression of RAR- and RXR-mediated induction of tissue transglutaminase. Toxicol Sci 68(1):102-108. PMID:12075115
  • West JA, Williams KJ, Toskala E, Nishio SJ, Fleschner CA, Forman HJ, Buckpitt AR, Plopper CG. 2002. Induction of tolerance to naphthalene in Clara cells is dependent on a stable phenotypic adaptation favoring maintenance of the glutathione pool. Am J Pathol 160(3):1115-1127. PMID:11891208
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