Superfund Research Program
Training Core
Project Leader: Timothy D. Phillips
Grant Number: P42ES004917
Funding Period: 1995-2008
Project-Specific Links
Publications
2018
- Zheng X, Dupuis KT, Aly NA, Zhou Y, Smith FB, Tang K, Smith RD, Baker ES. 2018. Utilizing ion mobility spectrometry and mass spectrometry for the analysis of polycyclic aromatic hydrocarbons, polychlorinated biphenyls, polybrominated diphenyl ethers and their metabolites. Anal Chim Acta 1037:265-273. doi:10.1016/j.aca.2018.02.054 PMID:30292301 PMCID:PMC6223027
2001
- McDougal A, Gupta MS, Morrow D, Ramamoorthy K, Lee J, Safe SH. 2001. Methyl-substituted diindolylmethanes as inhibitors of estrogen-induced growth of T47D cells and mammary tumors in rats. Breast Cancer Res Treat 66(2):147-157. PMID:11437101
- Safe SH, McDougal A, Gupta MS, Ramamoorthy K. 2001. Selective Ah receptor modulators (SAhRMs): progress towards development of a new class of inhibitors of breast cancer growth. Journal of Women's Cancer 3:37-45.
2000
- McDougal A, Gupta MS, Ramamoorthy K, Sun G, Safe SH. 2000. Inhibition of carcinogen-induced rat mammary tumor growth and other estrogen-dependent responses by symmetrical dihalo-substituted analogs of diindolylmethane. Cancer Lett 151(2):169-179. PMID:10738111
- Yoon K, Pallaroni L, Ramamoorthy K, Gaido KW, Safe SH. 2000. Ligand structure-dependent differences in activation of estrogen receptor alpha in human HepG2 liver and U2 osteogenic cancer cell lines. Mol Cell Endocrinol 162(1-2):211-220. PMID:10854714
1999
- Ramamoorthy K, Gupta MS, Sun G, McDougal A, Safe SH. 1999. 3,3',4,4'-Tetrachlorobiphenyl exhibits antiestrogenic and antitumorigenic activity in the rodent uterus and mammary and in human breast cancer cells. Carcinogenesis 20:115-123. PMID:9934858
- Ramamoorthy K, McDougal A, Safe SH. 1999. Structure-Ah receptor agonist/binding activity relationships of various chlorine-substituted diindolylmethane compounds. Organohalogen Compounds 42:363-367.
1998
- Gaido KW, Dohme L, Wang F, Chen I, Blankvoort B, Ramamoorthy K, Safe SH. 1998. Comparative estrogenic activity of wine extracts and organochlorine pesticide residues in food. Environ Health Perspect 106S:1347-1351. PMID:9860891
- Ramamoorthy K, Navo M, Gupta MS, Safe SH. 1998. AhR-mediated antiestrogenicity of diindolylmethane and analogs in vivo and in vitro. Organohalogen Compounds 37:321-324.
1997
- Connor K, Ramamoorthy K, Moore M, Mustain M, Chen I, Safe SH, Zacharewski TR, Gillesby B, Joyeux A, Belaguer P. 1997. Hydroxylated polychlorinated biphenyls (PCBs) as estrogens and antiestrogens: structure-activity relationships. Toxicol Appl Pharmacol 145:111-123. PMID:9221830
- Ramamoorthy K, Safe SH. 1997. The antiestrogenic activity of 3,3',4,4'-tetrachlorobiphenyl in the immature mouse uterus. Organohalogen Compounds 34:334-337.
- Ramamoorthy K, Vyhlidal C, Wang F, Chen I, Safe SH, McDonnell DP, Leonard LS, Gaido KW. 1997. Additive estrogenic activities of a binary mixture of 2',4',6'-trichloro- and 2',3',4',5'-tetrachloro-4-biphenylol. Toxicol Appl Pharmacol 147:93-100. PMID:9356311
- Ramamoorthy K, Wang F, Chen I, Norris JD, McDonnell DP, Gaido KW, Bocchinfuso WP, Korach KS, Safe SH. 1997. Potency of combined estrogenic pesticides. Science 275:405. PMID:9005556
- Ramamoorthy K, Wang F, Chen I, Norris JD, McDonnell DP, Leonard LS, Gaido KW, Bocchinfuso WP, Korach KS, Safe SH. 1997. Estrogenic activity of a dieldrin/toxaphene mixture in the mouse uterus, MCF-7 human breast cancer cells, and yeast-based estrogen receptor assays: no apparent synergism. Endocrinology 138:1520-1527. PMID:9075711
- Safe SH, Connor K, Ramamoorthy K, Gaido KW, Maness SC. 1997. Human exposure to endocrine-active chemicals: hazard assessment problems. Regul Toxicol Pharmacol 26:52-58. PMID:9339480
1996
- Connor K, Ramamoorthy K, Safe SH. 1996. The effects of hydroxylated polychlorinated biphenyls (PCBs) on the immature rat and mouse uterus. Organohalogen Compounds 29:312-315.