Superfund Research Program
Genetic Analysis
Project Leaders: Jia Chen, James G. Wetmur
Grant Number: P42ES007384
Funding Period: 2001 - 2006
Project-Specific Links
- Project Summary
Publications
2005
- Wetmur JG, Kumar M, Zhang L, Palomeque C, Wallenstein S, Chen J. 2005. Molecular haplotyping by linking emulsion PCR: analysis of paraoxonase 1 haplotypes and phenotypes. Nucleic Acids Res 33(8):2615-2619. PMID:15886392
2003
- Chen J, Hunter DJ, Stampfer MJ, Kyte C, Chan W, Wetmur JG, Selhub J, Ma J. 2003. Polymorphism in the thymidylate synthase promoter enhancer region modifies the risk and survival of colorectal cancer. Cancer Epidemiol Biomarkers Prev 12(10):958-962. PMID:14578129
- Chen J, Ma J, Stampfer MJ, Palomeque C, Selhub J, Hunter DJ. 2003. Linkage disequilibrium between the 677C>T and 1298 A>C polymorphisms in human methylenetetrahydrofolate reductase gene and their contributions to risk of colorectal cancer. Pharmacogenet Genomics 12(4):339-342. PMID:12042673
2002
- Chen J, Gerner S, Higuchi R, Berkowitz GS, Godbold JH, Wetmur JG. 2002. Kinetic PCR on pooled DNA: a high efficiency alternative in genetic epidemiologic studies. Cancer Epidemiol Biomarkers Prev 11:131-136.
- Chen J, Ma J, Stampfer MJ, Hines LM, Selhub J, Hunter DJ. 2002. Alcohol dehydrogenase 3 genotype is not predictive for risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev 10:1303-1304. PMID:11751450
- Wetmur JG, Kumar M, Berkowitz GS, Chen J. 2002. Increased influence of genetic variation on paraoxonase gene expression in neonates. Environ Mol Mutagen 93(Suppl33):67.
2001
- Chen J, Higuchi R, Gerner S, Berkowitz GS, Wetmur JG. 2001. Kinetic PCR on pooled DNA: a high-throughput, high-efficiency alternative in genetic epidemiologic studies. Proc Am Assoc Cancer Res 42:283.
- Chen J, Stampfer MJ, Ma J, Selhub J, Malinow MR, Hennekens CH, Hunter DJ. 2001. Influence of a methionine synthase (D919G) polymorphism on plasma homocysteine and folate levels and relation to risk of myocardial infarction. Atherosclerosis 154:667-672. PMID:11257268
2000
- Gonzalez S, Rosenfeld A, Szeto D, Wetmur JG. 2000. The Ruv proteins of Thermotoga maritima: branch migration and resolution of Holliday junctions. Biochim Biophys Acta 1494(3):217-225. PMID:11121578