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Project Publications: University of California-San Diego: Endocrine Disruptors in the Environment and their Influence

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Superfund Research Program

Endocrine Disruptors in the Environment and their Influence

Project Leader: Christopher K. Glass
Grant Number: P42ES010337
Funding Period: 2000-2010

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  • Boyd AE, Dunlop CS, Wong L, Radic Z, Taylor PW, Johnson DA. 2004. Nanosecond dynamics of acetylcholinesterase near the active center gorge. J Biol Chem 279(25):26612-26618. PMID:15078872
  • Comoletti D, De Jaco A, Jennings LL, Flynn RE, Gaietta G, Tsigelny I, Ellisman MH, Taylor PW. 2004. The Arg451Cys-neuroligin-3 mutation associated with autism reveals a defect in protein processing. J Neurosci 24(20):4889-4893. PMID:15152050
  • Cunard R, Eto Y, Muljadi JT, Glass CK, Kelly CJ, Ricote M. 2004. Repression of IFN-gamma expression by peroxisome proliferator-activated receptor gamma. J Immunol 172(12):7530-7536. PMID:15187132
  • Hoffman RC, Jennings LL, Tsigelny I, Comoletti D, Flynn RE, Sudhof TC, Taylor PW. 2004. Structural characterization of recombinant soluble rat neuroligin 1: Mapping of secondary structure and glycosylation by mass spectrometry. Biochemistry 43(6):1496-1506. PMID:14769026
  • Valledor AF, Hsu L, Ogawa S, Sawka-Verhelle D, Karin M, Glass CK. 2004. Activation of liver X receptors and retinoid X receptors prevents bacterial-induced macrophage apoptosis. Proc Natl Acad Sci U S A 101(51):17813-17818. PMID:15601766


  • George KM, Schule T, Sandoval LE, Jennings LL, Taylor PW, Thompson CM. 2003. Differentiation between acetylcholinesterase and the organophosphate-inhibited form using antibodies and the correlation of antibody recognition with reactivation mechanism and rate. J Biol Chem 278(46):45512-45518. PMID:12933813
  • Welch JS, Ricote M, Akiyama TE, Gonzalez FJ, Glass CK. 2003. PPARgamma and PPARdelta negatively regulate specific subsets of lipopolysaccharide and IFN-gamma target genes in macrophages. Proc Natl Acad Sci U S A 100(11):6712-6717. PMID:12740443


  • Akiyama TE, Sakai S, Lambert G, Nicol CJ, Matsusue K, Pimprale S, Lee Y, Ricote M, Glass CK, Brewer HB, Gonzalez FJ. 2002. Conditional disruption of the PPARg gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux. Mol Cell Biol 22(8):2607-2619. PMID:11909955
  • Cunard R, DiCampli D, Archer DC, Stevenson JL, Ricote M, Glass CK, Kelly CJ. 2002. WY14,643, a PPAR alpha ligand, has profound effects on immune responses in vivo. J Immunol 169(12):6806-6812. PMID:12471112
  • Cunard R, Ricote M, DiCampli D, Archer DC, Kahn DA, Glass CK, Kelly CJ. 2002. Regulation of cytokine expression by ligands of peroxisome proliferator activated receptors. J Immunol 168(6):2795-2802. PMID:11884448
  • Shi J, Radic Z, Taylor PW. 2002. Inhibitors of different structure induce distinguishing conformations in the omega loop, Cys69-Cys96, of mouse acetylcholinesterase. J Biol Chem 277(45):43301-43308. doi:10.1074/jbc.M204391200 PMID:12196517
  • Welch JS, Escoubet-Lozach L, Sykes DB, Liddiard K, Greaves DR, Glass CK. 2002. TH2 cytokines and allergic challenge induce Ym1 expression in macrophages by a STAT6-dependent mechanism. J Biol Chem 277(45):42821-42829. PMID:12215441


  • Glass CK. 2001. Potential roles of the peroxisome proliferator-activated receptor-g in macrophage biology and atherosclerosis. Journal of Endocrinology 169:461-464. PMID:11375116
  • Glass CK, Witzum JL. 2001. Atherosclerosis, the road ahead. Cell 104:503-516. PMID:11239408
  • Murata T, Kurokawa R, Krones A, Tatsumi K, Ishii M, Taki T, Masuno M, Ohashi H, Yanagisawa M, Rosenfeld MG, Glass CK, Hayashi Y. 2001. Defect of histone acetyltransferase activity of the nuclear transcriptional coactivator CBP in Rubinstein-Taybi Syndrome. Hum Mol Genet 10(10):1071-1076. PMID:11331617
  • Rosenfeld MG, Glass CK. 2001. Coregulator codes of transcriptional regulation by nuclear receptors. J Biol Chem 276:36865-36868. PMID:11459854
  • Straus DS, Glass CK. 2001. Cyclopentenone prostaglandins: new insights on biological activities and cellular targets. Med Res Rev 21(3):185-210. PMID:11301410


  • Ricote M, Welch JS, Glass CK. 2000. Regulation of macrophage gene expression bythe peroxisome proliferator-actived receptor-gamma. Horm Res 54:275-280. PMID:11595817
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