Skip Navigation

Project Publications: Duke University: Altering the Balance of Adipogenic and Osteogenic Regulatory Pathways from Early Life Exposure to HPCs and AOPEs

Superfund Research Program

Altering the Balance of Adipogenic and Osteogenic Regulatory Pathways from Early Life Exposure to HPCs and AOPEs

Project Leader: Heather M. Stapleton
Co-Investigators: P. Lee Ferguson, Seth W. Kullman (North Carolina State University)
Grant Number: P42ES010356
Funding Period: 2017-2022

Project-Specific Links

Publications

  • Stapleton HM, Olshan A. Cancer Research Advisory Panel Recommendations. In: Cancer Research Advisory Panel.

2022

  • Markovich Z, Hartman JH, Ryde IT, Hershberger KA, Joyce A, Ferguson PL, Meyer JN. 2022. Mild pentachlorophenol-mediated uncoupling of mitochondria depletes ATP but does not cause an oxidized redox state or dopaminergic neurodegeneration in Caenorhabditis elegans. Curr Res Toxicol 3:doi:10.1016/j.crtox.2022.100084 PMID:35957653 PMCID:PMC9361317

2021

  • Patisaul HB, Behl M, Birnbaum LS, Blum A, Diamond ML, Fernandez SR, Hogberg HT, Kwiatkowski C, Page JD, Soehl A, Stapleton HM. 2021. Beyond cholinesterase inhibition: Developmental neurotoxicity of organophosphate ester flame retardants and plasticizers. Environ Health Perspect 129(10):105001. doi:10.1289/EHP9285 PMID:34612677 PMCID:PMC8493874

2020

  • Cooper EM, Rushing R, Hoffman K, Phillips AL, Hammel SC, Zylka MJ, Stapleton HM. 2020. Strobilurin fungicides in house dust: Is wallboard a source?. J Expo Sci Environ Epidemiol 30:247-252. doi:10.1038/s41370-019-0180-z PMID:31636368 PMCID:PMC7044059
  • Kassotis CD, Herkert N, Hammel SC, Hoffman K, Xia Q, Kullman SW, Sosa JA, Stapleton HM. 2020. Thyroid receptor antagonism of chemicals extracted from personal silicone wristbands within a papillary thyroid cancer pilot study. Environ Sci Technol 54:15296-15312. doi:10.1021/acs.est.0c05972 PMID:33185092 PMCID:PMC7819617
  • Phillips AL, Herkert N, Ulrich JC, Hartman JH, Ruis MT, Cooper EM, Ferguson PL, Stapleton HM. 2020. In vitro metabolism of isopropylated and tert-butylated triarylphosphate esters using human liver subcellular fractions. Chem Res Toxicol 33:1428-1441. doi:10.1021/acs.chemrestox.0c00002 PMID:32129605 PMCID:PMC7508416

2019

2018

  • Hammel SC, Phillips AL, Hoffman K, Stapleton HM. 2018. Evaluating the use of silicone wristbands to measure personal exposure to brominated flame retardants. Environ Sci Technol 52:11875-11885. doi:10.1021/acs.est.8b03755 PMID:30216050 PMCID:PMC6445795
  • Kassotis CD, Kollitz EM, Ferguson PL, Stapleton HM. 2018. Nonionic ethoxylated surfactants induce adipogenesis in 3T3-L1 cells. Toxicol Sci 162(1):124-136. doi:10.1093/toxsci/kfx234 PMID:29106673 PMCID:PMC625695
  • Kollitz EM, De Carbonnel L, Stapleton HM, Ferguson PL. 2018. The affinity of brominated phenolic compounds for human and zebrafish thyroid receptor beta: Influence of chemical structure. Toxicol Sci doi:10.1093/toxsci/kfy028 PMID:29409039
  • Kollitz EM, Kassotis CD, Hoffman K, Ferguson PL, Sosa JA, Stapleton HM. 2018. Chemical mixtures isolated from house dust disrupt thyroid receptor beta signaling. Environ Sci Technol 52:11857-11864. doi:10.1021/acs.est.8b03283 PMID:30212187
  • Lefevre E, Bossa N, Gardner CM, Gehrke GE, Cooper EM, Stapleton HM, Hsu-Kim H, Gunsch C. 2018. Biochar and activated carbon act as promising amendments for promoting the microbial debromination of tetrabromobisphenol A. Water Res 128:102-110. doi:10.1016/j.watres.2017.09.047 PMID:29091801 PMCID:PMC5796758
  • Luz AL, Kassotis CD, Stapleton HM, Meyer JN. 2018. The high-production volume fungicide pyraclostrobin induces triglyceride accumulation associated with mitochondrial dysfunction, and promotes adipocyte differentiation independent of PPARgamma activation, in 3T3-L1 cells. Toxicology 393:150-159. doi:10.1016/j.tox.2017.11.010 PMID:29127035 PMCID:PMC5726929

2017

Back
to Top